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5TSU
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BU of 5tsu by Molmil
Active conformation for Engineered human cystathionine gamma lyase (E59N, R119L, E339V) to depleting methionine
分子名称: CYSTEINE, Cystathionine gamma-lyase, METHIONINE, ...
著者Yan, W, Zhang, Y.
登録日2016-10-31
公開日2017-10-11
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Snapshots of an Engineered Cystathionine-gamma-lyase Reveal the Critical Role of Electrostatic Interactions in the Active Site.
Biochemistry, 56, 2017
4Y5T
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BU of 4y5t by Molmil
Structure of FtmOx1 apo with metal Iron
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, COBALT (II) ION, FE (II) ION, ...
著者Yan, W, Zhang, Y.
登録日2015-02-12
公開日2015-11-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.949 Å)
主引用文献Endoperoxide formation by an alpha-ketoglutarate-dependent mononuclear non-haem iron enzyme.
Nature, 527, 2015
4Y5S
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BU of 4y5s by Molmil
Structure of FtmOx1 with a-Ketoglutarate as co-substrate
分子名称: 2-OXOGLUTARIC ACID, COBALT (II) ION, FE (II) ION, ...
著者Yan, W, Zhang, Y.
登録日2015-02-12
公開日2015-11-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.543 Å)
主引用文献Endoperoxide formation by an alpha-ketoglutarate-dependent mononuclear non-haem iron enzyme.
Nature, 527, 2015
6V65
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BU of 6v65 by Molmil
Crystal structure of KRAS(GMPPNP)-NF1(GRD)-SPRED1 complex
分子名称: FORMIC ACID, GTPase KRas, MAGNESIUM ION, ...
著者Yan, W, Simanshu, D.K.
登録日2019-12-04
公開日2020-07-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.763 Å)
主引用文献Structural Insights into the SPRED1-Neurofibromin-KRAS Complex and Disruption of SPRED1-Neurofibromin Interaction by Oncogenic EGFR.
Cell Rep, 32, 2020
6V6F
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BU of 6v6f by Molmil
Crystal structure of Q61L KRAS(GMPPNP)-NF1(GRD)-SPRED1(EVH1) complex
分子名称: FORMIC ACID, GTPase KRas, MAGNESIUM ION, ...
著者Yan, W, Simanshu, D.K.
登録日2019-12-05
公開日2020-07-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.542 Å)
主引用文献Structural Insights into the SPRED1-Neurofibromin-KRAS Complex and Disruption of SPRED1-Neurofibromin Interaction by Oncogenic EGFR.
Cell Rep, 32, 2020
3SQD
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BU of 3sqd by Molmil
Crystal structure of human PTIP BRCT5/6-gamma H2AX complex
分子名称: Histone H2A.x, PAX-interacting protein 1
著者Yan, W, Shao, Z.H.
登録日2011-07-05
公開日2011-11-09
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.153 Å)
主引用文献Crystal structure of human PTIP BRCT5/6-gamma H2AX
To be Published
5TT2
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BU of 5tt2 by Molmil
Inactive conformation of engineered human cystathionine gamma lyase (E59N, R119L, E339V) to depleting methionine
分子名称: Cystathionine gamma-lyase, SULFATE ION
著者Yan, W, Zhang, Y.
登録日2016-10-31
公開日2017-10-11
最終更新日2019-11-27
実験手法X-RAY DIFFRACTION (2.949 Å)
主引用文献Structural Snapshots of an Engineered Cystathionine-gamma-lyase Reveal the Critical Role of Electrostatic Interactions in the Active Site.
Biochemistry, 56, 2017
2FDP
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BU of 2fdp by Molmil
Crystal structure of beta-secretase complexed with an amino-ethylene inhibitor
分子名称: Beta-secretase 1, N1-((2S,3S,5R)-3-AMINO-6-(4-FLUOROPHENYLAMINO)-5-METHYL-6-OXO-1-PHENYLHEXAN-2-YL)-N3,N3-DIPROPYLISOPHTHALAMIDE
著者Yang, W, Lu, W, Lu, Y, Zhong, M, Sun, J, Thomas, A.E, Wilkinson, J.M, Fucini, R.V, Lam, M, Randal, M, Shi, X.P, Jacobs, J.W, McDowell, R.S, Gordon, E.M, Ballinger, M.D.
登録日2005-12-14
公開日2006-01-24
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Aminoethylenes: a tetrahedral intermediate isostere yielding potent inhibitors of the aspartyl protease BACE-1.
J.Med.Chem., 49, 2006
7X2E
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BU of 7x2e by Molmil
Structure of USH1C PDZ2 and coiled-coil in complex with CDHR2 C-terminal tail
分子名称: Cadherin-related family member 2, GLYCEROL, Harmonin
著者Yan, W, Chen, G, Li, J.
登録日2022-02-25
公開日2022-07-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of the Harmonin PDZ2 and coiled-coil domains in a complex with CDHR2 tail and its implications.
Faseb J., 36, 2022
3SZ5
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BU of 3sz5 by Molmil
Crystal Structure of LHK-Exo in complex with 5-phosphorylated oligothymidine (dT)4
分子名称: 5'-D(P*TP*TP*TP*T)-3', Exonuclease, MAGNESIUM ION
著者Yang, W, Chen, W.Y, Wang, H, Zhang, Q, Zhou, W, Bartlam, M, Watt, R.M, Rao, Z.
登録日2011-07-18
公開日2012-02-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural and functional insight into the mechanism of an alkaline exonuclease from Laribacter hongkongensis.
Nucleic Acids Res., 39, 2011
1L8Z
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BU of 1l8z by Molmil
Solution structure of HMG box 5 in human upstream binding factor
分子名称: upstream binding factor 1
著者Yang, W, Xu, Y, Wu, J, Zeng, W, Shi, Y.
登録日2002-03-22
公開日2002-06-05
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure and DNA binding property of the fifth HMG box domain in comparison with the first HMG box domain in human upstream binding factor
Biochemistry, 42, 2003
1L8Y
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BU of 1l8y by Molmil
Solution structure of HMG box 5 in human upstream binding factor
分子名称: upstream binding factor 1
著者Yang, W, Xu, Y, Wu, J, Zeng, W, Shi, Y.
登録日2002-03-22
公開日2002-06-05
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure and DNA binding property of the fifth HMG box domain in comparison with the first HMG box domain in human upstream binding factor
Biochemistry, 42, 2003
1T6W
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BU of 1t6w by Molmil
RATIONAL DESIGN OF A CALCIUM-BINDING ADHESION PROTEIN NMR, 20 STRUCTURES
分子名称: CALCIUM ION, hypothetical protein XP_346638
著者Yang, W, Wilkins, A.L, Ye, Y, Liu, Z.-R, Urbauer, J.L, Kearney, A, van der Merwe, P.A, Yang, J.J.
登録日2004-05-07
公開日2005-02-15
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Design of a calcium-binding protein with desired structure in a cell adhesion molecule.
J.Am.Chem.Soc., 127, 2005
3LXF
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BU of 3lxf by Molmil
Crystal Structure of [2Fe-2S] Ferredoxin Arx from Novosphingobium aromaticivorans
分子名称: FE2/S2 (INORGANIC) CLUSTER, Ferredoxin
著者Yang, W, Bell, S.G, Wang, H, Bartlam, M, Wong, L.L, Rao, Z.
登録日2010-02-25
公開日2010-06-23
最終更新日2014-02-12
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular characterization of a class I P450 electron transfer system from Novosphingobium aromaticivorans DSM12444
J.Biol.Chem., 285, 2010
3LXI
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BU of 3lxi by Molmil
Crystal Structure of Camphor-Bound CYP101D1
分子名称: CAMPHOR, Cytochrome P450, PHOSPHATE ION, ...
著者Yang, W, Bell, S.G, Wang, H, Bartlam, M, Wong, L.L, Rao, Z.
登録日2010-02-25
公開日2010-06-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Molecular characterization of a class I P450 electron transfer system from Novosphingobium aromaticivorans DSM12444
J.Biol.Chem., 285, 2010
3LXH
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BU of 3lxh by Molmil
Crystal Structure of Cytochrome P450 CYP101D1
分子名称: 1,4-DIETHYLENE DIOXIDE, Cytochrome P450, PHOSPHATE ION, ...
著者Yang, W, Bell, S.G, Wang, H, Bartlam, M, Wong, L.L, Rao, Z.
登録日2010-02-25
公開日2010-06-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Molecular characterization of a class I P450 electron transfer system from Novosphingobium aromaticivorans DSM12444
J.Biol.Chem., 285, 2010
3LXD
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BU of 3lxd by Molmil
Crystal Structure of Ferredoxin Reductase ArR from Novosphingobium aromaticivorans
分子名称: FAD-dependent pyridine nucleotide-disulphide oxidoreductase, FLAVIN-ADENINE DINUCLEOTIDE
著者Yang, W, Bell, S.G, Wang, H, Bartlam, M, Wong, L.L, Rao, Z.
登録日2010-02-25
公開日2010-06-23
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular characterization of a class I P450 electron transfer system from Novosphingobium aromaticivorans DSM12444
J.Biol.Chem., 285, 2010
3NV6
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BU of 3nv6 by Molmil
Crystal Structure of Camphor-Bound CYP101D2
分子名称: CAMPHOR, Cytochrome P450, DI(HYDROXYETHYL)ETHER, ...
著者Yang, W, Bell, S.G, Wang, H, Zhou, W.H, Bartlam, M, Wong, L.L, Rao, Z.
登録日2010-07-08
公開日2010-11-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The structure of CYP101D2 unveils a potential path for substrate entry into the active site
Biochem.J., 433, 2011
3NV5
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BU of 3nv5 by Molmil
Crystal Structure of Cytochrome P450 CYP101D2
分子名称: Cytochrome P450, DI(HYDROXYETHYL)ETHER, PROTOPORPHYRIN IX CONTAINING FE
著者Yang, W, Bell, S.G, Wang, H, Zhou, W.H, Bartlam, M, Wong, L.L, Rao, Z.
登録日2010-07-08
公開日2010-11-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献The structure of CYP101D2 unveils a potential path for substrate entry into the active site
Biochem.J., 433, 2011
3SYY
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BU of 3syy by Molmil
Crystal Structure of an alkaline exonuclease (LHK-Exo) from Laribacter hongkongensis
分子名称: Exonuclease, MAGNESIUM ION
著者Yang, W, Chen, W.Y, Wang, H, Zhang, Q, Zhou, W, Bartlam, M, Watt, R.M, Rao, Z.
登録日2011-07-18
公開日2012-02-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and functional insight into the mechanism of an alkaline exonuclease from Laribacter hongkongensis.
Nucleic Acids Res., 39, 2011
3SZ4
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BU of 3sz4 by Molmil
Crystal Structure of LHK-Exo in complex with dAMP
分子名称: 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, Exonuclease, MAGNESIUM ION
著者Yang, W, Chen, W.Y, Wang, H, Zhang, Q, Zhou, W, Bartlam, M, Watt, R.M, Rao, Z.
登録日2011-07-18
公開日2012-02-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Structural and functional insight into the mechanism of an alkaline exonuclease from Laribacter hongkongensis.
Nucleic Acids Res., 39, 2011
1RNH
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BU of 1rnh by Molmil
STRUCTURE OF RIBONUCLEASE H PHASED AT 2 ANGSTROMS RESOLUTION BY MAD ANALYSIS OF THE SELENOMETHIONYL PROTEIN
分子名称: RIBONUCLEASE HI, SULFATE ION
著者Yang, W, Hendrickson, W.A, Crouch, R.J, Satow, Y.
登録日1990-07-11
公開日1991-10-15
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of ribonuclease H phased at 2 A resolution by MAD analysis of the selenomethionyl protein.
Science, 249, 1990
1GDT
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BU of 1gdt by Molmil
CRYSTAL STRUCTURE OF A SITE-SPECIFIC RECOMBINASE, GAMMA-DELTA RESOLVASE COMPLEXED WITH A 34 BP CLEAVAGE SITE
分子名称: PROTEIN (GAMMA DELTA RESOLVASE), SITE I OF RES DNA
著者Yang, W, Steitz, T.A.
登録日1995-04-11
公開日1996-04-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of the site-specific recombinase gamma delta resolvase complexed with a 34 bp cleavage site.
Cell(Cambridge,Mass.), 82, 1995
8T83
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BU of 8t83 by Molmil
X-ray crystal structure of PfA-M1(M462K)
分子名称: Aminopeptidase N, GLYCEROL, ZINC ION
著者Yang, W, Drinkwater, N, Webb, C.T, McGowan, S.
登録日2023-06-21
公開日2024-06-26
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Conformational dynamics of the Plasmodium falciparum M1 aminopeptidase.
To Be Published
6B3X
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BU of 6b3x by Molmil
Crystal structure of CstF-50 in complex with CstF-77
分子名称: Cleavage stimulation factor subunit 1, Cleavage stimulation factor subunit 3
著者Yang, W, Hsu, P, Yang, F, Song, J.E, Varani, G.
登録日2017-09-25
公開日2017-11-29
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Reconstitution of the CstF complex unveils a regulatory role for CstF-50 in recognition of 3'-end processing signals.
Nucleic Acids Res., 46, 2018

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