4XJC
| dCTP deaminase-dUTPase from Bacillus halodurans | 分子名称: | DI(HYDROXYETHYL)ETHER, Deoxycytidine triphosphate deaminase, MAGNESIUM ION, ... | 著者 | Oehlenschlaeger, C, Loevgreen, M, Willemoes, M, Harris, P. | 登録日 | 2015-01-08 | 公開日 | 2015-03-18 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Bacillus halodurans Strain C125 Encodes and Synthesizes Enzymes from Both Known Pathways To Form dUMP Directly from Cytosine Deoxyribonucleotides. Appl.Environ.Microbiol., 81, 2015
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2QXX
| Bifunctional dCTP deaminase: dUTPase from Mycobacterium tuberculosis in complex with dTTP | 分子名称: | Deoxycytidine triphosphate deaminase, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ... | 著者 | Christophersen, S, Harris, P, Willemoes, M. | 登録日 | 2007-08-13 | 公開日 | 2008-02-19 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Mechanism of dTTP inhibition of the bifunctional dCTP deaminase:dUTPase encoded by Mycobacterium tuberculosis. J.Mol.Biol., 376, 2008
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2G3N
| Crystal structure of the Sulfolobus solfataricus alpha-glucosidase MalA in complex with beta-octyl-glucopyranoside | 分子名称: | Alpha-glucosidase, octyl beta-D-glucopyranoside | 著者 | Ernst, H.A, Lo Leggio, L, Willemoes, M, Leonard, G, Blum, P, Larsen, S. | 登録日 | 2006-02-20 | 公開日 | 2006-05-02 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Structure of the Sulfolobus solfataricus alpha-Glucosidase: Implications for Domain Conservation and Substrate Recognition in GH31. J.Mol.Biol., 358, 2006
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2G3M
| Crystal structure of the Sulfolobus solfataricus alpha-glucosidase MalA | 分子名称: | Alpha-glucosidase | 著者 | Ernst, H.A, Lo Leggio, L, Willemoes, M, Leonard, G, Blum, P, Larsen, S. | 登録日 | 2006-02-20 | 公開日 | 2006-05-02 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Structure of the Sulfolobus solfataricus alpha-Glucosidase: Implications for Domain Conservation and Substrate Recognition in GH31. J.Mol.Biol., 358, 2006
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2V9X
| E138D variant of Escherichia coli dCTP deaminase in complex with dUTP | 分子名称: | DEOXYCYTIDINE TRIPHOSPHATE DEAMINASE, DEOXYURIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Thymark, M, Johansson, E, Larsen, S, Willemoes, M. | 登録日 | 2007-08-28 | 公開日 | 2007-11-20 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Mutational Analysis of the Nucleotide Binding Site of Escherichia Coli Dctp Deaminase. Arch.Biochem.Biophys., 470, 2008
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3NVA
| Dimeric form of CTP synthase from Sulfolobus solfataricus | 分子名称: | CTP synthase | 著者 | Harris, P, Willemoes, M, Lauritsen, I, Johansson, E, Jensen, K.F. | 登録日 | 2010-07-08 | 公開日 | 2010-09-08 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.504 Å) | 主引用文献 | Structure of the dimeric form of CTP synthase from Sulfolobus solfataricus Acta Crystallogr.,Sect.F, 67, 2011
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1XS4
| dCTP deaminase from Escherichia coli- E138A mutant enzyme in complex with dCTP | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, Deoxycytidine triphosphate deaminase, MAGNESIUM ION | 著者 | Johansson, E, Fano, M, Bynck, J.H, Neuhard, J, Larsen, S, Sigurskjold, B.W, Christensen, U, Willemoes, M. | 登録日 | 2004-10-18 | 公開日 | 2004-12-21 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | 主引用文献 | Structures of dCTP deaminase from Escherichia coli with bound substrate and product: reaction mechanism and determinants of mono- and bifunctionality for a family of enzymes J.Biol.Chem., 280, 2005
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1XS1
| dCTP deaminase from Escherichia coli in complex with dUTP | 分子名称: | DEOXYURIDINE-5'-TRIPHOSPHATE, Deoxycytidine triphosphate deaminase, MAGNESIUM ION | 著者 | Johansson, E, Fano, M, Bynck, J.H, Neuhard, J, Larsen, S, Sigurskjold, B.W, Christensen, U, Willemoes, M. | 登録日 | 2004-10-18 | 公開日 | 2004-12-21 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structures of dCTP deaminase from Escherichia coli with bound substrate and product: reaction mechanism and determinants of mono- and bifunctionality for a family of enzymes J.Biol.Chem., 280, 2005
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1XS6
| dCTP deaminase from Escherichia coli. E138A mutant enzyme in complex with dUTP | 分子名称: | DEOXYURIDINE-5'-TRIPHOSPHATE, Deoxycytidine triphosphate deaminase, MAGNESIUM ION | 著者 | Johansson, E, Fano, M, Bynck, J.H, Neuhard, J, Larsen, S, Sigurskjold, B.W, Christensen, U, Willemoes, M. | 登録日 | 2004-10-18 | 公開日 | 2004-12-21 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structures of dCTP deaminase from Escherichia coli with bound substrate and product: reaction mechanism and determinants of mono- and bifunctionality for a family of enzymes J.Biol.Chem., 280, 2005
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4A6A
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2QLP
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8QZK
| Catalytic core of endo-alpha-N-acetylgalactosaminidase from Bifidobacterium longum (EngBF) concieved by deep network hallucination: dEngBF4 Hexagonal form | 分子名称: | ENDO-ALPHA-N-ACETYLGALACTOSAMINIDASE | 著者 | Aghajari, N, Hansen, A.L, Thiesen, F.F, Crehuet, R, Marcos, E, Willemoes, M. | 登録日 | 2023-10-27 | 公開日 | 2024-03-06 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Carving out a Glycoside Hydrolase Active Site for Incorporation into a New Protein Scaffold Using Deep Network Hallucination. Acs Synth Biol, 13, 2024
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2J4Q
| Crystal structure of a E138A Escherichia coli dCTP deaminase mutant enzyme in complex with dTTP | 分子名称: | DEOXYCYTIDINE TRIPHOSPHATE DEAMINASE, MAGNESIUM ION, THYMIDINE-5'-DIPHOSPHATE, ... | 著者 | Johansson, E, Thymark, M, Bynck, J.H, Fanoe, M, Larsen, S, Willemoes, M. | 登録日 | 2006-09-05 | 公開日 | 2007-08-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Regulation of Dctp Deaminase from Escherichia Coli by Nonallosteric Dttp Binding to an Inactive Form of the Enzyme FEBS J., 274, 2007
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2J4H
| Crystal structure of a H121A Escherichia coli dCTP deaminase mutant enzyme | 分子名称: | DEOXYCYTIDINE DIPHOSPHATE, DEOXYCYTIDINE TRIPHOSPHATE DEAMINASE, MAGNESIUM ION | 著者 | Johansson, E, Thymark, M, Bynck, J.H, Fanoe, M, Larsen, S, Willemoes, M. | 登録日 | 2006-08-31 | 公開日 | 2007-08-07 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Regulation of Dctp Deaminase from Escherichia Coli by Nonallosteric Dttp Binding to an Inactive Form of the Enzyme FEBS J., 274, 2007
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3GF0
| Bifunctional dCTP deaminase-dUTPase mutant enzyme variant E145Q from Methanocaldococcus jannaschii in complex with pyrophosphate and magnesium | 分子名称: | MAGNESIUM ION, PYROPHOSPHATE 2-, dCTP deaminase, ... | 著者 | Siggaard, J.H.B, Johansson, E, Vognsen, T, Helt, S.S, Harris, P, Willemoes, M. | 登録日 | 2009-02-26 | 公開日 | 2009-03-10 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | Pre-steady State Kinetic and Structural Evidence for a Concerted Biofunctionality in dCTP deaminase-dUTPase from Methanocaldococcus jannaschii To be Published
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1UX1
| Bacillus subtilis cytidine deaminase with a Cys53His and an Arg56Gln substitution | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CYTIDINE DEAMINASE, TETRAHYDRODEOXYURIDINE, ... | 著者 | Johansson, E, Neuhard, J, Willemoes, M, Larsen, S. | 登録日 | 2004-02-18 | 公開日 | 2004-05-20 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Structural, Kinetic, and Mutational Studies of the Zinc Ion Environment in Tetrameric Cytidine Deaminase Biochemistry, 43, 2004
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1UWZ
| Bacillus subtilis cytidine deaminase with an Arg56 - Ala substitution | 分子名称: | CYTIDINE DEAMINASE, TETRAHYDRODEOXYURIDINE, ZINC ION | 著者 | Johansson, E, Neuhard, J, Willemoes, M, Larsen, S. | 登録日 | 2004-02-18 | 公開日 | 2004-05-20 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Structural, Kinetic, and Mutational Studies of the Zinc Ion Environment in Tetrameric Cytidine Deaminase Biochemistry, 43, 2004
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1UX0
| Bacillus subtilis cytidine deaminase with an Arg56 - Gln substitution | 分子名称: | CYTIDINE DEAMINASE, TETRAHYDRODEOXYURIDINE, ZINC ION | 著者 | Johansson, E, Neuhard, J, Willemoes, M, Larsen, S. | 登録日 | 2004-02-18 | 公開日 | 2004-05-20 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Structural, Kinetic, and Mutational Studies of the Zinc Ion Environment in Tetrameric Cytidine Deaminase Biochemistry, 43, 2004
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2QPU
| Sugar tongs mutant S378P in complex with acarbose | 分子名称: | 1,2-ETHANEDIOL, 1,5-anhydro-4-O-(4,6-dideoxy-4-{[(1S,2S,3S,4R,5S,6R)-2,3,4,6-tetrahydroxy-5-methylcyclohexyl]amino}-alpha-D-glucopyranosyl)-D-glucitol, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, ... | 著者 | Aghajari, N, Jensen, M.H, Tranier, S, Haser, R. | 登録日 | 2007-07-25 | 公開日 | 2008-07-01 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The 'pair of sugar tongs' site on the non-catalytic domain C of barley alpha-amylase participates in substrate binding and activity Febs J., 274, 2007
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5J7D
| Computationally Designed Thioredoxin dF106 | 分子名称: | COPPER (II) ION, Designed Thioredoxin dF106 | 著者 | Horowitz, S, Johansen, N, Olsen, J.G, Winther, J.R. | 登録日 | 2016-04-06 | 公開日 | 2016-10-05 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Computational Redesign of Thioredoxin Is Hypersensitive toward Minor Conformational Changes in the Backbone Template. J.Mol.Biol., 428, 2016
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3G6W
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8QYE
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1VST
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2QPS
| "Sugar tongs" mutant Y380A in complex with acarbose | 分子名称: | Alpha-amylase type A isozyme, CALCIUM ION | 著者 | Aghajari, N, Jensen, M.H, Tranier, S, Haser, R. | 登録日 | 2007-07-25 | 公開日 | 2008-02-12 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The 'pair of sugar tongs' site on the non-catalytic domain C of barley alpha-amylase participates in substrate binding and activity Febs J., 274, 2007
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2HXB
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