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8BPA
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BU of 8bpa by Molmil
Cryo-EM structure of the human SIN3B histone deacetylase complex at 3.7 Angstrom
分子名称: CALCIUM ION, Histone deacetylase 2, Isoform 2 of Paired amphipathic helix protein Sin3b, ...
著者Wan, M.S.M, Muhammad, R, Koliopolous, M.G, Alfieri, C.
登録日2022-11-16
公開日2023-05-10
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Mechanism of assembly, activation and lysine selection by the SIN3B histone deacetylase complex.
Nat Commun, 14, 2023
8BPB
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Cryo-EM structure of the human SIN3B histone deacetylase core complex at 2.8 Angstrom
分子名称: ACETATE ION, CALCIUM ION, Histone deacetylase 2, ...
著者Wan, M.S.M, Muhammad, R, Koliopolous, M.G, Alfieri, C.
登録日2022-11-16
公開日2023-05-10
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Mechanism of assembly, activation and lysine selection by the SIN3B histone deacetylase complex.
Nat Commun, 14, 2023
8BPC
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BU of 8bpc by Molmil
Cryo-EM structure of the human SIN3B histone deacetylase core complex with SAHA at 2.8 Angstrom
分子名称: CALCIUM ION, Histone deacetylase 2, Isoform 2 of Paired amphipathic helix protein Sin3b, ...
著者Wan, M.S.M, Muhammad, R, Koliopolous, M.G, Alfieri, C.
登録日2022-11-16
公開日2023-05-10
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Mechanism of assembly, activation and lysine selection by the SIN3B histone deacetylase complex.
Nat Commun, 14, 2023
8C60
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BU of 8c60 by Molmil
Cryo-EM structure of the human SIN3B full-length complex at 3.4 Angstrom resolution
分子名称: CALCIUM ION, Histone deacetylase 2, Isoform 2 of Paired amphipathic helix protein Sin3b, ...
著者Alfieri, C, Wan, S.M, Muhammad, R.
登録日2023-01-10
公開日2023-05-10
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Mechanism of assembly, activation and lysine selection by the SIN3B histone deacetylase complex.
Nat Commun, 14, 2023
1KS4
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BU of 1ks4 by Molmil
The structure of Aspergillus niger endoglucanase-palladium complex
分子名称: Endoglucanase A, PALLADIUM ION
著者Khademi, S, Zhang, D, Swanson, S.M, Wartenberg, A, Witte, C, Meyer, E.F.
登録日2002-01-10
公開日2003-01-21
最終更新日2017-02-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Determination of the structure of an endoglucanase from Aspergillus niger and its mode of inhibition by palladium chloride.
Acta Crystallogr.,Sect.D, 58, 2002
1KS5
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BU of 1ks5 by Molmil
Structure of Aspergillus niger endoglucanase
分子名称: Endoglucanase A
著者Khademi, S, Zhang, D, Swanson, S.M, Wartenberg, A, Witte, C, Meyer, E.F.
登録日2002-01-10
公開日2003-01-21
最終更新日2017-02-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Determination of the structure of an endoglucanase from Aspergillus niger and its mode of inhibition by palladium chloride.
Acta Crystallogr.,Sect.D, 58, 2002
1CXV
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BU of 1cxv by Molmil
STRUCTURE OF RECOMBINANT MOUSE COLLAGENASE-3 (MMP-13)
分子名称: 2-{4-[4-(4-CHLORO-PHENOXY)-BENZENESULFONYL]-TETRAHYDRO-PYRAN-4-YL}-N-HYDROXY-ACETAMIDE, CALCIUM ION, PROTEIN (COLLAGENASE-3), ...
著者Botos, I, Meyer, E, Swanson, S.M, Lemaitre, V, Eeckhout, Y, Meyer, E.F.
登録日1999-08-30
公開日2000-08-30
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of recombinant mouse collagenase-3 (MMP-13).
J.Mol.Biol., 292, 1999
1EQ9
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BU of 1eq9 by Molmil
CRYSTAL STRUCTURE OF FIRE ANT CHYMOTRYPSIN COMPLEXED TO PMSF
分子名称: CHYMOTRYPSIN, phenylmethanesulfonic acid
著者Botos, I, Meyer, E, Nguyen, M.H, Swanson, S.M, Meyer, E.F.
登録日2000-04-03
公開日2000-10-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The structure of an insect chymotrypsin.
J.Mol.Biol., 298, 2000
8SLO
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BU of 8slo by Molmil
Plasmodium falciparum M1 aminopeptidase bound to selective inhibitor MIPS2673
分子名称: 2-hydroxy-N-[(1R)-2-(hydroxyamino)-2-oxo-1-(3',4',5'-trifluoro[1,1'-biphenyl]-4-yl)ethyl]-2-methylpropanamide, GLYCEROL, M1 family aminopeptidase, ...
著者McGowan, S.M, Drinkwater, N.
登録日2023-04-24
公開日2024-04-03
最終更新日2024-07-24
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Chemoproteomics validates selective targeting of Plasmodium M1 alanyl aminopeptidase as an antimalarial strategy.
Elife, 13, 2024
1NL6
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BU of 1nl6 by Molmil
Crystal Structure Of The Cysteine Protease Human Cathepsin K In Complex With A Covalent Azepanone Inhibitor
分子名称: 5-(2-MORPHOLIN-4-YLETHOXY)BENZOFURAN-2-CARBOXYLIC ACID ((S)-3-METHYL-1-{(S)-3-OXO-1-[2-(3-PYRIDIN-2-YLPHENYL)ACETYL]AZEPAN-4-YLCARBAMOYL}BUTYL)AMIDE, Cathepsin K
著者Smith, W.W, Janson, C.A, Zhao, B.
登録日2003-01-06
公開日2003-01-14
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Azepanone-based inhibitors of human and rat cathepsin K
J.Med.Chem., 44, 2001
1NLJ
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CRYSTAL STRUCTURE OF THE CYSTEINE PROTEASE HUMAN CATHEPSIN K IN COMPLEX WITH A COVALENT AZEPANONE INHIBITOR
分子名称: BENZOFURAN-2-CARBOXYLIC ACID {(S)-3-METHYL-1-[3-OXO-1-(PYRIDIN-2-YLSULFONYL)AZEPAN-4-YLCARBAMOYL]BUTYL}AMIDE, CATHEPSIN K
著者Smith, W.W, Janson, C.A, Zhao, B.
登録日2003-01-07
公開日2003-01-14
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Azepanone-Based Inhibitors of Human and Rat Cathepsin K
J.Med.Chem., 44, 2001
1VP9
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DC26 MUTANT OF VACCINIA VIRUS PROTEIN VP39 IN COMPLEX WITH S-ADENOSYLHOMOCYSTEINE
分子名称: S-ADENOSYL-L-HOMOCYSTEINE, VP39
著者Hodel, A.E, Gershon, P.D, Quiocho, F.A.
登録日1996-11-23
公開日1997-09-17
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Specific protein recognition of an mRNA cap through its alkylated base.
Nat.Struct.Biol., 4, 1997
1VP3
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VACCINIA VIRUS PROTEIN VP39 IN COMPLEX WITH S-ADENOSYLHOMOCYSTEINE
分子名称: S-ADENOSYL-L-HOMOCYSTEINE, VP39
著者Hodel, A.E, Gershon, P.D, Quiocho, F.A.
登録日1996-11-21
公開日1997-09-17
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Specific protein recognition of an mRNA cap through its alkylated base.
Nat.Struct.Biol., 4, 1997
1V39
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BU of 1v39 by Molmil
DC26 MUTANT OF VACCINIA VIRUS PROTEIN VP39 IN COMPLEX WITH S-ADENOSYLHOMOCYSTEINE AND M7G(5')PPPG
分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, S-ADENOSYL-L-HOMOCYSTEINE, VP39
著者Hodel, A.E, Gershon, P.D, Quiocho, F.A.
登録日1996-12-16
公開日1997-09-17
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Specific protein recognition of an mRNA cap through its alkylated base.
Nat.Struct.Biol., 4, 1997
2VP3
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BU of 2vp3 by Molmil
DC26 MUTANT OF VACCINIA VIRUS PROTEIN VP39 IN COMPLEX WITH S-ADENOSYLHOMOCYSTEINE AND M7G(5')PPPG
分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, S-ADENOSYL-L-HOMOCYSTEINE, VP39
著者Hodel, A.E, Gershon, P.D, Quiocho, F.A.
登録日1996-12-16
公開日1997-09-17
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Specific protein recognition of an mRNA cap through its alkylated base.
Nat.Struct.Biol., 4, 1997
5Y7W
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BU of 5y7w by Molmil
Crystal structure of the Nco-A1 PAS-B domain with YL-2
分子名称: Nuclear receptor coactivator 1, YL-2 peptide
著者Lee, Y.J, Yoon, H.S, Lee, J.H, Bae, J.H, Song, J.Y, Lim, H.S.
登録日2017-08-18
公開日2017-11-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Targeted Inhibition of the NCOA1/STAT6 Protein-Protein Interaction
J. Am. Chem. Soc., 139, 2017
3E7O
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BU of 3e7o by Molmil
Crystal Structure of JNK2
分子名称: Mitogen-activated protein kinase 9, N-{3-[5-(1H-1,2,4-triazol-3-yl)-1H-indazol-3-yl]phenyl}furan-2-carboxamide
著者Kuglstatter, A, Villasenor, A.G.
登録日2008-08-18
公開日2008-09-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献The crystal structure of JNK2 reveals conformational flexibility in the MAP kinase insert and indicates its involvement in the regulation of catalytic activity.
J.Mol.Biol., 383, 2008
1P39
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BU of 1p39 by Molmil
DC26 MUTANT OF VACCINIA VIRUS PROTEIN VP39 IN COMPLEX WITH S-ADENOSYLHOMOCYSTEINE AND M7G(5')PPPG
分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, S-ADENOSYL-L-HOMOCYSTEINE, VP39
著者Hodel, A.E, Gershon, P.D, Quiocho, F.A.
登録日1996-12-16
公開日1997-09-17
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Specific protein recognition of an mRNA cap through its alkylated base.
Nat.Struct.Biol., 4, 1997
7EVR
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BU of 7evr by Molmil
Crystal structure of hnRNP L RRM2 in complex with SETD2
分子名称: Heterogeneous nuclear ribonucleoprotein L, SHI domain from Histone-lysine N-methyltransferase SETD2
著者Li, F.D, Wang, S.M.
登録日2021-05-22
公開日2021-10-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis of the interaction between SETD2 methyltransferase and hnRNP L paralogs for governing co-transcriptional splicing.
Nat Commun, 12, 2021
7EVS
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BU of 7evs by Molmil
Crystal structure of hnRNP LL RRM2 in complex with SETD2
分子名称: Heterogeneous nuclear ribonucleoprotein L-like, SHI domain from Histone-lysine N-methyltransferase SETD2, SULFATE ION
著者Li, F.D, Wang, S.M.
登録日2021-05-22
公開日2021-10-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural basis of the interaction between SETD2 methyltransferase and hnRNP L paralogs for governing co-transcriptional splicing.
Nat Commun, 12, 2021
3P3E
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Crystal Structure of the PSEUDOMONAS AERUGINOSA LpxC/LPC-009 complex
分子名称: N-[(1S,2R)-2-hydroxy-1-(hydroxycarbamoyl)propyl]-4-(4-phenylbuta-1,3-diyn-1-yl)benzamide, NITRATE ION, SODIUM ION, ...
著者Lee, C.-J, Zhou, P.
登録日2010-10-04
公開日2011-01-05
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Species-specific and inhibitor-dependent conformations of LpxC: implications for antibiotic design.
Chem.Biol., 18, 2011
8GN3
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The crystal structure of ZBTB10 ZF1-2 in complex with telomeric vairant repeat TTGGGG
分子名称: DNA (5'-D(*AP*TP*AP*CP*AP*AP*CP*CP*CP*CP*A)-3'), DNA (5'-D(*TP*TP*GP*GP*GP*GP*TP*TP*GP*TP*A)-3'), ZINC ION, ...
著者Li, F.D, Wang, S.M.
登録日2022-08-22
公開日2023-08-30
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural insights into the recognition of telomeric variant repeat TTGGGG by broad-complex, tramtrack and bric-a-brac - zinc finger protein ZBTB10.
J.Biol.Chem., 299, 2023
8GN4
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The crystal structure of ZBTB10 ZF1-2 R767Q in complex with telomeric DNA TTAGGG
分子名称: DNA (5'-D(*AP*TP*AP*TP*AP*AP*CP*CP*CP*TP*A)-3'), DNA (5'-D(*TP*TP*AP*GP*GP*GP*TP*TP*AP*TP*A)-3'), ZINC ION, ...
著者Li, F.D, Wang, S.M.
登録日2022-08-22
公開日2023-08-30
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insights into the recognition of telomeric variant repeat TTGGGG by broad-complex, tramtrack and bric-a-brac - zinc finger protein ZBTB10.
J.Biol.Chem., 299, 2023
3P3G
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Crystal Structure of the Escherichia coli LpxC/LPC-009 complex
分子名称: 4-ethynyl-N-[(1S,2R)-2-hydroxy-1-(oxocarbamoyl)propyl]benzamide, DIMETHYL SULFOXIDE, N-[(1S,2R)-2-hydroxy-1-(hydroxycarbamoyl)propyl]-4-(4-phenylbuta-1,3-diyn-1-yl)benzamide, ...
著者Lee, C.-J, Zhou, P.
登録日2010-10-04
公開日2011-01-05
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Species-specific and inhibitor-dependent conformations of LpxC: implications for antibiotic design.
Chem.Biol., 18, 2011
3P3C
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Crystal Structure of the Aquifex aeolicus LpxC/LPC-009 complex
分子名称: N-[(1S,2R)-2-hydroxy-1-(hydroxycarbamoyl)propyl]-4-(4-phenylbuta-1,3-diyn-1-yl)benzamide, PHOSPHATE ION, UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase, ...
著者Lee, C.-J, Zhou, P.
登録日2010-10-04
公開日2011-01-05
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Species-specific and inhibitor-dependent conformations of LpxC: implications for antibiotic design.
Chem.Biol., 18, 2011

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