1VP9

DC26 MUTANT OF VACCINIA VIRUS PROTEIN VP39 IN COMPLEX WITH S-ADENOSYLHOMOCYSTEINE

Summary for 1VP9

Entry DOI	10.2210/pdb1vp9/pdb
Descriptor	VP39, S-ADENOSYL-L-HOMOCYSTEINE (3 entities in total)
Functional Keywords	methyltransferase, rna cap, poly(a) polymerase, vaccinia, mrna processing, transcription
Biological source	Vaccinia virus
Cellular location	Virion (Potential): P07617
Total number of polymer chains	1
Total formula weight	37518.11
Authors	Hodel, A.E.,Gershon, P.D.,Quiocho, F.A. (deposition date: 1996-11-23, release date: 1997-09-17, Last modification date: 2024-05-22)
Primary citation	Hodel, A.E.,Gershon, P.D.,Shi, X.,Wang, S.M.,Quiocho, F.A. Specific protein recognition of an mRNA cap through its alkylated base. Nat.Struct.Biol., 4:350-354, 1997 Cited by PubMed Abstract: The specific binding of N7-methylguanine cap analogues to the RNA methyltransferase VP39 was observed through X-ray crystallography, providing a prototypical structure for a complex between a protein and an mRNA 5' cap. PubMed: 9145102 DOI: 10.1038/nsb0597-350 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation