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8Q5H
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BU of 8q5h by Molmil
Human KMN network (outer kinetochore)
分子名称: Kinetochore protein Spc24, Kinetochore protein Spc25, Kinetochore scaffold 1, ...
著者Raisch, T, Polley, S, Vetter, I, Musacchio, A, Raunser, S.
登録日2023-08-09
公開日2024-02-14
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Insights into human outer kinetochore assembly and force transmission from a structure-function analysis of the KMN network
To Be Published
4JHN
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BU of 4jhn by Molmil
The crystal structure of the RPGR RCC1-like domain
分子名称: X-linked retinitis pigmentosa GTPase regulator
著者Waetzlich, D, Vetter, I, Wittinghofer, A, Ismail, S.
登録日2013-03-05
公開日2013-04-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The interplay between RPGR, PDE-delta and Arl2/3 regulate the ciliary targeting of farnesylated cargo.
Embo Rep., 14, 2013
5T4R
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BU of 5t4r by Molmil
NMR solution structure of the Nav1.7 selective spider venom-derived peptide Pn3a
分子名称: Mu-theraphotoxin-Pn3a
著者Rosengren, K.J, Armstrong, D.A, Vetter, I.
登録日2016-08-30
公開日2017-09-06
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Pharmacological characterisation of the highly Na V 1.7 selective spider venom peptide Pn3a.
Sci Rep, 7, 2017
4JHP
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The crystal structure of the RPGR RCC1-like domain in complex with PDE6D
分子名称: Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta, X-linked retinitis pigmentosa GTPase regulator
著者Waetzlich, D, Vetter, I, Wittinghofer, A, Ismail, S.
登録日2013-03-05
公開日2013-04-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The interplay between RPGR, PDE-delta and Arl2/3 regulate the ciliary targeting of farnesylated cargo.
Embo Rep., 14, 2013
1A12
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REGULATOR OF CHROMOSOME CONDENSATION (RCC1) OF HUMAN
分子名称: REGULATOR OF CHROMOSOME CONDENSATION 1
著者Renault, L, Nassar, N, Vetter, I, Becker, J, Roth, M, Wittinghofer, A.
登録日1997-12-19
公開日1999-01-13
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The 1.7 A crystal structure of the regulator of chromosome condensation (RCC1) reveals a seven-bladed propeller.
Nature, 392, 1998
6CEG
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BU of 6ceg by Molmil
Solution NMR structure of the omega conotoxin MoVIB from Conus moncuri
分子名称: conotoxin MoVIB
著者Rosengren, K.J.
登録日2018-02-11
公開日2018-03-07
最終更新日2020-01-01
実験手法SOLUTION NMR
主引用文献Novel analgesic omega-conotoxins from the vermivorous cone snail Conus moncuri provide new insights into the evolution of conopeptides.
Sci Rep, 8, 2018
6PPC
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BU of 6ppc by Molmil
Solution structure of conotoxin MiXXVIIA
分子名称: Conopeptide phi-MiXXVIIA
著者Daly, N.L, Dekan, Z, Jin, A.H, Alewood, P.F.
登録日2019-07-06
公開日2019-08-14
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Conotoxin phi-MiXXVIIA from the Superfamily G2 Employs a Novel Cysteine Framework that Mimics Granulin and Displays Anti-Apoptotic Activity.
Angew. Chem. Int. Ed. Engl., 56, 2017
7SAW
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BU of 7saw by Molmil
Mu-conotoxin KIIIA isomer 2
分子名称: Mu-conotoxin KIIIA
著者Schroeder, C.I, Tran, H.N.T.
登録日2021-09-23
公開日2022-05-25
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural and functional insights into the inhibition of human voltage-gated sodium channels by mu-conotoxin KIIIA disulfide isomers.
J.Biol.Chem., 298, 2022
8UXR
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BU of 8uxr by Molmil
TxVIIB,U-superfamily conotoxin
分子名称: Conotoxin Tx6.5
著者Raffaelli, T, Daly, N.
登録日2023-11-09
公開日2024-03-27
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural analysis of a U-superfamily conotoxin containing a mini-granulin fold: Insights into key features that distinguish between the ICK and granulin folds.
J.Biol.Chem., 300, 2024
8FD4
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BU of 8fd4 by Molmil
Solution structure of mu-theraphotoxin Cg4a from Chinese tarantula Chilobrachys jingzhao
分子名称: Jingzhaotoxin F7-10.36
著者Sharma, G, Jia, X, Chin, Y.K.Y, Mobli, M.
登録日2022-12-01
公開日2023-11-08
実験手法SOLUTION NMR
主引用文献Solution structure of mu-theraphotoxin Cg4a from Chinese tarantula Chilobrachys jingzhao
To Be Published
8FEY
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BU of 8fey by Molmil
Solution structure of Pmu1a
分子名称: Pmu1a toxin
著者Daly, N.L, Wilson, D.T.
登録日2022-12-07
公開日2023-03-29
最終更新日2023-08-02
実験手法SOLUTION NMR
主引用文献Pmu1a, a novel spider toxin with dual inhibitory activity at pain targets hNa V 1.7 and hCa V 3 voltage-gated channels.
Febs J., 290, 2023
4LFT
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BU of 4lft by Molmil
Structure of alpha-elapitoxin-Dpp2d isolated from Black Mamba (Dendroaspis polylepis) venom
分子名称: Alpha-elapitoxin-Dpp2a
著者Wang, C.I.A, Reeks, T, Lewis, R.J, Alewood, P.F, Durek, T.
登録日2013-06-27
公開日2014-06-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Isolation and Structural and Pharmacological Characterization of alpha-Elapitoxin-Dpp2d, an Amidated Three Finger Toxin from Black Mamba Venom.
Biochemistry, 53, 2014
6BL9
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BU of 6bl9 by Molmil
NMR Solution structure of U-SLPTX15-Sm2a
分子名称: Sm2a toxin
著者Harvey, P.J, Craik, D.J, Durek, T, Dash, T.J.
登録日2017-11-09
公開日2018-11-14
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献A Centipede Toxin Family Defines an Ancient Class of CS alpha beta Defensins.
Structure, 27, 2019
6WQR
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BU of 6wqr by Molmil
NMR solution structure of leech peptide HSTX-I
分子名称: HSTX-I
著者Schroeder, C.I, McMahon, K.L.
登録日2020-04-29
公開日2020-06-24
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Pharmacological activity and NMR solution structure of the leech peptide HSTX-I.
Biochem Pharmacol, 181, 2020
6X8R
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BU of 6x8r by Molmil
Pharmacological characterisation and NMR structure of the novel mu-conotoxin SxIIIC, a potent irreversible NaV channel inhibitor
分子名称: SxIIIC peptide
著者Schroeder, C.I, McMahon, K.L.
登録日2020-06-01
公開日2020-10-21
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Discovery, Pharmacological Characterisation and NMR Structure of the Novel μ-Conotoxin SxIIIC, a Potent and Irreversible Na V Channel Inhibitor.
Biomedicines, 8, 2020
8JZM
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BU of 8jzm by Molmil
The inhibitor of Toll-like receptor signaling o-vanillin binds covalently to MAL/TIRAP Lys-210
分子名称: Toll/interleukin-1 receptor domain-containing adapter protein
著者Rahaman, M.H, Jia, X, Maxwell, M.J, Mobli, M, Kobe, B.
登録日2023-07-05
公開日2024-05-01
実験手法SOLUTION NMR
主引用文献o-Vanillin binds covalently to MAL/TIRAP Lys-210 but independently inhibits TLR2.
J Enzyme Inhib Med Chem, 39, 2024
7JPM
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BU of 7jpm by Molmil
The solution structure of omega-theraphotoxin-Pm1b isolated from King Baboon spider
分子名称: Omega-theraphotoxin-Pm1b
著者Chin, Y.K.-Y, Ziegman, R, Alewood, P.F.
登録日2020-08-09
公開日2021-09-08
最終更新日2023-10-11
実験手法SOLUTION NMR
主引用文献Multitarget nociceptor sensitization by a promiscuous peptide from the venom of the King Baboon spider.
Proc.Natl.Acad.Sci.USA, 119, 2022
6VH8
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BU of 6vh8 by Molmil
NMR Solution Structure of Excelsatoxin A
分子名称: Excelsatoxin A
著者Harvey, P.J, Durek, T, Craik, D.J.
登録日2020-01-09
公開日2020-09-30
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Neurotoxic peptides from the venom of the giant Australian stinging tree.
Sci Adv, 6, 2020
4GOJ
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BU of 4goj by Molmil
The Crystal Structure of full length Arl3GppNHp in complex with UNC119a
分子名称: ADP-ribosylation factor-like protein 3, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Ismail, S, Xiang-Chen, Y, Miertzschke, M, Vetter, I, Koerner, C, Wittinghofer, A.
登録日2012-08-20
公開日2012-09-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for Arl3-specific release of myristoylated ciliary cargo from UNC119.
Embo J., 31, 2012
4GOK
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BU of 4gok by Molmil
The Crystal structure of Arl2GppNHp in complex with UNC119a
分子名称: ADP-ribosylation factor-like protein 2, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Ismail, S, Xiang-Chen, Y, Miertzschke, M, Vetter, I, Koerner, C, Wittinghofer, A.
登録日2012-08-20
公開日2012-09-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for Arl3-specific release of myristoylated ciliary cargo from UNC119.
Embo J., 31, 2012
5T3M
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BU of 5t3m by Molmil
Solution structure of a triple mutant of HwTx-IV - a potent blocker of Nav1.7
分子名称: Mu-theraphotoxin-Hs2a
著者Rahnama, S, Sharma, G, Mobli, M.
登録日2016-08-25
公開日2017-09-06
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The structure, dynamics and selectivity profile of a NaV1.7 potency-optimised huwentoxin-IV variant.
PLoS ONE, 12, 2017
5FZW
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High resolution solution NMR structure of the spider venom peptide U3- scytotoxin-Sth1h
分子名称: Venom peptide U3-SYTX-Sth1h
著者Loening, N.M.
登録日2016-03-15
公開日2016-06-08
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Characterization of Three Venom Peptides from the Spitting Spider Scytodes Thoracica.
Plos One, 11, 2016
5FZV
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High resolution solution NMR structure of the spider venom peptide U3- scytotoxin-Sth1a
分子名称: Venom peptide U3-SYTX-Sth1a
著者Loening, N.M.
登録日2016-03-15
公開日2016-06-08
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Characterization of Three Venom Peptides from the Spitting Spider Scytodes Thoracica.
Plos One, 11, 2016
5FZX
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High resolution solution NMR structure of the spider venom peptide U5- scytotoxin-Sth1a
分子名称: U5-SCYTOTOXIN-STH1A
著者Loening, N.M.
登録日2016-03-15
公開日2016-06-08
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Characterization of Three Venom Peptides from the Spitting Spider Scytodes Thoracica.
Plos One, 11, 2016
7R6P
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Solution structure of peptide toxin MIITX2-Mg1a from the venom of the Australian giant red bull ant Myrmecia gulosa
分子名称: U-myrmeciitoxin(02)-Mg1a
著者Chin, Y.K, Eagle, D, Bankala, K, Robinson, S.D.
登録日2021-06-23
公開日2022-02-09
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献A peptide toxin in ant venom mimics vertebrate EGF-like hormones to cause long-lasting hypersensitivity in mammals.
Proc.Natl.Acad.Sci.USA, 119, 2022

 

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