1PBA
 
 | | THE NMR STRUCTURE OF THE ACTIVATION DOMAIN ISOLATED FROM PORCINE PROCARBOXYPEPTIDASE B | | 分子名称: | PROCARBOXYPEPTIDASE B | | 著者 | Vendrell, J, Wider, G, Billeter, M, Aviles, F.X, Wuthrich, K. | | 登録日 | 1991-11-18 | | 公開日 | 1993-10-31 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The NMR structure of the activation domain isolated from porcine procarboxypeptidase B.
EMBO J., 10, 1991
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1QMU
 | | Duck carboxypeptidase D domain II | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBOXYPEPTIDASE GP180 RESIDUES 503-882, SULFATE ION, ... | | 著者 | Gomis-Rueth, F.X, Coll, M, Aviles, F.X, Vendrell, J, Fricker, L.D. | | 登録日 | 1999-10-06 | | 公開日 | 2000-10-13 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal Structure of Avian Carboxypeptidase D Domain II : A Prototype for the Regulatory Metallocarboxypeptidase Subfamily
Embo J., 18, 1999
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3KGQ
 | | Carboxypeptidase A liganded to an organic small-molecule: conformational changes | | 分子名称: | ACETONE, CITRIC ACID, Carboxypeptidase A1, ... | | 著者 | Fernandez, D, Boix, E, Pallares, I, Aviles, F.X, Vendrell, J. | | 登録日 | 2009-10-29 | | 公開日 | 2010-10-27 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural and Functional Analysis of the Complex between Citrate and the Zinc Peptidase Carboxypeptidase A
Enzyme Res, 2011, 2011
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5OM9
 | | Crystal structure of the human CARBOXYPEPTIDASE A1 in complex with a thiirane mechanism-based inhibitor | | 分子名称: | (2~{R})-4-methyl-2-[(1~{S})-1-sulfanylethyl]pentanoic acid, Carboxypeptidase A1, ZINC ION | | 著者 | Gallego, P, Granados, C, Fernandez, D, Pallares, I, Covaleda, G, Aviles, F.X, Vendrell, J, Reverter, D. | | 登録日 | 2017-07-28 | | 公開日 | 2017-08-09 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Discovery of Mechanism-Based Inactivators for Human Pancreatic Carboxypeptidase A from a Focused Synthetic Library.
ACS Med Chem Lett, 8, 2017
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2V77
 | | Crystal Structure of Human Carboxypeptidase A1 | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CARBOXYPEPTIDASE A1, OCTANE-1,3,5,7-TETRACARBOXYLIC ACID, ... | | 著者 | Pallares, I, Fernandez, D, Comellas-Bigler, M, Fernandez-Recio, J, Ventura, S, Aviles, F.X, Vendrell, J. | | 登録日 | 2007-07-27 | | 公開日 | 2008-07-01 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.603 Å) | | 主引用文献 | Direct interaction between a human digestive protease and the mucoadhesive poly(acrylic acid).
Acta Crystallogr. D Biol. Crystallogr., D64, 2008
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1AYE
 | | HUMAN PROCARBOXYPEPTIDASE A2 | | 分子名称: | PROCARBOXYPEPTIDASE A2, ZINC ION | | 著者 | Garcia-Saez, I, Reverte, D, Vendrell, J, Aviles, F.X, Coll, M. | | 登録日 | 1997-11-03 | | 公開日 | 1999-01-13 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The three-dimensional structure of human procarboxypeptidase A2. Deciphering the basis of the inhibition, activation and intrinsic activity of the zymogen.
EMBO J., 16, 1997
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4K90
 | | Extracellular metalloproteinase from Aspergillus | | 分子名称: | BORIC ACID, CALCIUM ION, Extracellular metalloproteinase mep, ... | | 著者 | Fernandez, D, Russi, S, Vendrell, J, Monod, M, Pallares, I. | | 登録日 | 2013-04-19 | | 公開日 | 2013-10-23 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | A functional and structural study of the major metalloprotease secreted by the pathogenic fungus Aspergillus fumigatus.
Acta Crystallogr.,Sect.D, 69, 2013
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2BOA
 | | Human procarboxypeptidase A4. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBOXYPEPTIDASE A4, ... | | 著者 | Garcia-Castellanos, R, Bonet-Figueredo, R, Pallares, I, Ventura, S, Aviles, F.X, Vendrell, J, Gomis-Ruth, F.X. | | 登録日 | 2005-04-08 | | 公開日 | 2005-12-13 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Detailed Molecular Comparison between the Inhibition Mode of A/B-Type Carboxypeptidases in the Zymogen State and by the Endogenous Inhibitor Latexin.
Cell.Mol.Life Sci., 62, 2005
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2PCU
 | | Human carboxypeptidase A4 in complex with a cleaved hexapeptide. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ASPARTIC ACID, Carboxypeptidase A4, ... | | 著者 | Bayes, A, Fernandez, D, Sola, M, Marrero, A, Garcia-Pique, S, Aviles, F.X, Vendrell, J, Gomis-Ruth, F.X. | | 登録日 | 2007-03-30 | | 公開日 | 2007-04-17 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Caught after the Act: a human A-type metallocarboxypeptidase in a product complex with a cleaved hexapeptide.
Biochemistry, 46, 2007
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1H8L
 | | Duck Carboxypeptidase D Domain II in complex with GEMSA | | 分子名称: | (2-GUANIDINOETHYLMERCAPTO)SUCCINIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Gomis-Rueth, F.X, Coll, M, Aviles, F.X, Vendrell, J, Fricker, L.D. | | 登録日 | 2001-02-09 | | 公開日 | 2002-02-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The crystal structure of the inhibitor-complexed carboxypeptidase D domain II and the modeling of regulatory carboxypeptidases.
J. Biol. Chem., 276, 2001
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1JQG
 | | Crystal Structure of the Carboxypeptidase A from Helicoverpa Armigera | | 分子名称: | ZINC ION, carboxypeptidase A | | 著者 | Estebanez-Perpina, E, Bayes, A, Vendrell, J, Jongsma, M.A, Bown, D.P, Gatehouse, J.A, Huber, R, Bode, W, Aviles, F.X, Reverter, D. | | 登録日 | 2001-08-07 | | 公開日 | 2002-08-07 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of a novel mid-gut procarboxypeptidase from the cotton pest Helicoverpa armigera.
J.Mol.Biol., 313, 2001
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1KWM
 | | Human procarboxypeptidase B: Three-dimensional structure and implications for thrombin-activatable fibrinolysis inhibitor (TAFI) | | 分子名称: | CITRIC ACID, Procarboxypeptidase B, ZINC ION | | 著者 | Pereira, P.J.B, Segura-Martin, S, Ferrer-Orta, C, Vendrell, J, Aviles, F.-X, Coll, M, Gomis-Rueth, F.-X. | | 登録日 | 2002-01-30 | | 公開日 | 2002-06-05 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Human procarboxypeptidase B: three-dimensional structure and implications for thrombin-activatable fibrinolysis inhibitor (TAFI).
J.Mol.Biol., 321, 2002
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2C1C
 | | Structural basis of the resistance of an insect carboxypeptidase to plant protease inhibitors | | 分子名称: | CARBOXYPEPTIDASE B, YTTRIUM ION, ZINC ION | | 著者 | Bayes, A, Comellas-Bigler, M, Rodriguez de la Vega, M, Maskos, K, Bode, W, Aviles, F.X, Jongsma, M.A, Beekwilder, J, Vendrell, J. | | 登録日 | 2005-09-12 | | 公開日 | 2005-10-19 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural Basis of the Resistance of an Insect Carboxypeptidase to Plant Protease Inhibitors.
Proc.Natl.Acad.Sci.USA, 102, 2005
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2BO9
 | | Human carboxypeptidase A4 in complex with human latexin. | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETONE, ... | | 著者 | Pallares, I, Bonet, R, Garcia-Castellanos, R, Ventura, S, Aviles, F.X, Vendrell, J, Gomis-Rueth, F.X. | | 登録日 | 2005-04-08 | | 公開日 | 2005-04-15 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure of Human Carboxypeptidase A4 with its Endogenous Protein Inhibitor, Latexin.
Proc.Natl.Acad.Sci.USA, 102, 2005
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1O6X
 | | NMR solution structure of the activation domain of human procarboxypeptidase A2 | | 分子名称: | PROCARBOXYPEPTIDASE A2 | | 著者 | Jimenez, M.A, Villegas, V, Santoro, J, Serrano, L, Vendrell, J, Aviles, F.X, Rico, M. | | 登録日 | 2002-10-17 | | 公開日 | 2003-01-30 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR Solution Structure of the Activation Domain of Human Procarboxypeptidase A2
Protein Sci., 12, 2003
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6I6Z
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3DGV
 | | Crystal structure of thrombin activatable fibrinolysis inhibitor (TAFI) | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Anand, K, Pallares, I, Valnickova, Z, Christensen, T, Schreuder, H, Enghild, J. | | 登録日 | 2008-06-16 | | 公開日 | 2008-07-22 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The crystal structure of thrombin-activable fibrinolysis inhibitor (TAFI) provides the structural basis for its intrinsic activity and the short half-life of TAFIa.
J.Biol.Chem., 283, 2008
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2ABZ
 | | Crystal structure of C19A/C43A mutant of leech carboxypeptidase inhibitor in complex with bovine carboxypeptidase A | | 分子名称: | Carboxypeptidase A1, Metallocarboxypeptidase inhibitor, ZINC ION | | 著者 | Arolas, J.L, Popowicz, G.M, Bronsoms, S, Aviles, F.X, Huber, R, Holak, T.A, Ventura, S. | | 登録日 | 2005-07-18 | | 公開日 | 2006-01-31 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | Study of a major intermediate in the oxidative folding of leech carboxypeptidase inhibitor: contribution of the fourth disulfide bond
J.Mol.Biol., 352, 2005
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3GLJ
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3I1U
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3HLP
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1DTV
 | | NMR STRUCTURE OF THE LEECH CARBOXYPEPTIDASE INHIBITOR (LCI) | | 分子名称: | CARBOXYPEPTIDASE INHIBITOR | | 著者 | Reverter, D, Fernandez-Catalan, C, Bode, W, Holak, T.A, Aviles, F.X. | | 登録日 | 2000-01-13 | | 公開日 | 2000-07-19 | | 最終更新日 | 2024-10-30 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of a novel leech carboxypeptidase inhibitor determined free in solution and in complex with human carboxypeptidase A2.
Nat.Struct.Biol., 7, 2000
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1DTD
 | | CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE LEECH CARBOXYPEPTIDASE INHIBITOR AND THE HUMAN CARBOXYPEPTIDASE A2 (LCI-CPA2) | | 分子名称: | CARBOXYPEPTIDASE A2, GLUTAMIC ACID, METALLOCARBOXYPEPTIDASE INHIBITOR, ... | | 著者 | Reverter, D, Fernandez-Catalan, C, Bode, W, Holak, T.A, Aviles, F.X. | | 登録日 | 2000-01-12 | | 公開日 | 2000-07-12 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structure of a novel leech carboxypeptidase inhibitor determined free in solution and in complex with human carboxypeptidase A2.
Nat.Struct.Biol., 7, 2000
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1ZFL
 | | Solution structure of III-A, the major intermediate in the oxidative folding of leech carboxypeptidase inhibitor | | 分子名称: | Metallocarboxypeptidase inhibitor | | 著者 | Arolas, J.L, D'Silva, L, Popowicz, G.M, Aviles, F.X, Holak, T.A, Ventura, S. | | 登録日 | 2005-04-20 | | 公開日 | 2005-09-13 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structural characterization and computational predictions of the major intermediate in oxidative folding of leech carboxypeptidase inhibitor
STRUCTURE, 13, 2005
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1ZFI
 | | Solution structure of the leech carboxypeptidase inhibitor | | 分子名称: | Metallocarboxypeptidase inhibitor | | 著者 | Arolas, J.L, D'Silva, L, Popowicz, G.M, Aviles, F.X, Holak, T.A, Ventura, S. | | 登録日 | 2005-04-20 | | 公開日 | 2005-09-13 | | 最終更新日 | 2024-10-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structural characterization and computational predictions of the major intermediate in oxidative folding of leech carboxypeptidase inhibitor
STRUCTURE, 13, 2005
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