1DTD

CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE LEECH CARBOXYPEPTIDASE INHIBITOR AND THE HUMAN CARBOXYPEPTIDASE A2 (LCI-CPA2)

Summary for 1DTD

DescriptorCARBOXYPEPTIDASE A2, METALLOCARBOXYPEPTIDASE INHIBITOR, ZINC ION, ... (5 entities in total)
Functional Keywordscarboxypeptidase a2, leech carboxypeptidase inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
More
Cellular locationSecreted P48052
Total number of polymer chains2
Total molecular weight40661.13
Authors
Reverter, D.,Fernandez-Catalan, C.,Bode, W.,Holak, T.A.,Aviles, F.X. (deposition date: 2000-01-12, release date: 2000-07-12, Last modification date: 2011-07-13)
Primary citation
Reverter, D.,Fernandez-Catalan, C.,Baumgartner, R.,Pfander, R.,Huber, R.,Bode, W.,Vendrell, J.,Holak, T.A.,Aviles, F.X.
Structure of a novel leech carboxypeptidase inhibitor determined free in solution and in complex with human carboxypeptidase A2.
Nat.Struct.Biol., 7:322-328, 2000
PubMed: 10742178 (PDB entries with the same primary citation)
DOI: 10.1038/74092
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.65 Å)
?

Structure validation

ClashscoreRamachandran outliersSidechain outliers60.8%3.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 1dtd
no rotation
Molmil generated image of 1dtd
rotated about x axis by 90°
Molmil generated image of 1dtd
rotated about y axis by 90°