1DTD
CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE LEECH CARBOXYPEPTIDASE INHIBITOR AND THE HUMAN CARBOXYPEPTIDASE A2 (LCI-CPA2)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CARBOXYPEPTIDASE A2 | polymer | 303 | 33660.9 | 1 | UniProt (P48052) Pfam (PF00246) | Homo sapiens (human) | |
| 2 | B (B) | METALLOCARBOXYPEPTIDASE INHIBITOR | polymer | 61 | 6787.6 | 1 | UniProt (P81511) | Hirudo medicinalis (medicinal leech) | |
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D (A) | GLUTAMIC ACID | non-polymer | 147.1 | 1 | Chemie (GLU) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 231 | Chemie (HOH) |
Sequence modifications
A: 363 - 665 (UniProt: P48052)
| PDB | External Database | Details |
|---|---|---|
| Ala 490 | - | insertion |
| Ser 587 | Arg 339 | conflict |
| Arg 588 | Ser 340 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 40448.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 212.5 | |
| All* | Total formula weight | 40661.1 |
