3DGV

Crystal structure of thrombin activatable fibrinolysis inhibitor (TAFI)

Summary for 3DGV

Entry DOI	10.2210/pdb3dgv/pdb
Descriptor	Carboxypeptidase B2, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total)
Functional Keywords	blood coagulation, fibrinolysis, carboxypeptidase, protein stability, glycoprotein, hydrolase, metal-binding, metalloprotease, protease, secreted, zymogen
Biological source	Bos taurus (bovine,cow,domestic cattle,domestic cow)
Cellular location	Secreted : Q2KIG3
Total number of polymer chains	3
Total formula weight	145884.59
Authors	Anand, K.,Pallares, I.,Valnickova, Z.,Christensen, T.,Schreuder, H.,Enghild, J. (deposition date: 2008-06-16, release date: 2008-07-22, Last modification date: 2023-11-01)
Primary citation	Anand, K.,Pallares, I.,Valnickova, Z.,Christensen, T.,Vendrell, J.,Wendt, K.U.,Schreuder, H.A.,Enghild, J.J.,Aviles, F.X. The crystal structure of thrombin-activable fibrinolysis inhibitor (TAFI) provides the structural basis for its intrinsic activity and the short half-life of TAFIa. J.Biol.Chem., 283:29416-29423, 2008 Cited by PubMed: 18669641 DOI: 10.1074/jbc.M804003200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation