6FAB
| THREE-DIMENSIONAL STRUCTURE OF MURINE ANTI-P-AZOPHENYLARSONATE FAB 36-71. 1. X-RAY CRYSTALLOGRAPHY, SITE-DIRECTED MUTAGENESIS, AND MODELING OF THE COMPLEX WITH HAPTEN | 分子名称: | IGG1-KAPPA 36-71 FAB (HEAVY CHAIN), IGG1-KAPPA 36-71 FAB (LIGHT CHAIN) | 著者 | Strong, R.K, Rose, D.R, Petsko, G.A, Sharon, J, Margolies, M.N. | 登録日 | 1991-01-17 | 公開日 | 1993-01-15 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Three-dimensional structure of murine anti-p-azophenylarsonate Fab 36-71. 1. X-ray crystallography, site-directed mutagenesis, and modeling of the complex with hapten. Biochemistry, 30, 1991
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3CII
| Structure of NKG2A/CD94 bound to HLA-E | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen peptide, HLA class I histocompatibility antigen, ... | 著者 | Strong, R.K, Kaiser, B.K, Pizarro, J.C. | 登録日 | 2008-03-11 | 公開日 | 2008-05-13 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (4.41 Å) | 主引用文献 | Structural basis for NKG2A/CD94 recognition of HLA-E. Proc.Natl.Acad.Sci.Usa, 105, 2008
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1KTL
| The human non-classical major histocompatibility complex molecule HLA-E | 分子名称: | BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAIN, ... | 著者 | Holmes, M.A, Strong, R.K. | 登録日 | 2002-01-16 | 公開日 | 2003-02-25 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | HLA-E allelic variants: Correlating differential expression, peptide affinities, crystal structures and thermal stabilities J.Biol.Chem., 278, 2003
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1KPR
| The human non-classical major histocompatibility complex molecule HLA-E | 分子名称: | BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAIN, ... | 著者 | Holmes, M.A, Strong, R.K. | 登録日 | 2002-01-02 | 公開日 | 2003-02-25 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | HLA-E allelic variants: Correlating differential expression, peptide affinities, crystal structures and thermal stabilities J.Biol.Chem., 278, 2003
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1MPU
| Crystal Structure of the free human NKG2D immunoreceptor | 分子名称: | NKG2-D type II integral membrane protein, PHOSPHATE ION | 著者 | McFarland, B.J, Kortemme, T, Baker, D, Strong, R.K. | 登録日 | 2002-09-12 | 公開日 | 2003-04-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Symmetry Recognizing Asymmetry: Analysis of the Interactions between the C-Type Lectin-like Immunoreceptor NKG2D and MHC
Class I-like Ligands Structure, 11, 2003
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4PP8
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3OMZ
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1HYR
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6O5D
| PYOCHELIN | 分子名称: | GLYCEROL, Neutrophil gelatinase-associated lipocalin, SULFATE ION | 著者 | Rupert, P.B, Strong, R.K, Clifton, M.C, Edwards, T.E, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2019-03-01 | 公開日 | 2019-09-11 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Parsing the functional specificity of Siderocalin/Lipocalin 2/NGAL for siderophores and related small-molecule ligands. J Struct Biol X, 2, 2019
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6OKD
| Crystal Structure of human transferrin receptor in complex with a cystine-dense peptide | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | 著者 | Finton, K.A.K, Rupert, P.B, Strong, R.K. | 登録日 | 2019-04-12 | 公開日 | 2020-04-15 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | A TfR-Binding Cystine-Dense Peptide Promotes Blood-Brain Barrier Penetration of Bioactive Molecules. J.Mol.Biol., 432, 2020
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3BY0
| Crystal structure of Siderocalin (NGAL, Lipocalin 2) W79A-R81A complexed with Ferric Enterobactin | 分子名称: | 2,3-DIHYDROXY-BENZOIC ACID, 2-(2,3-DIHYDROXY-BENZOYLAMINO)-3-HYDROXY-PROPIONIC ACID, FE (III) ION, ... | 著者 | Clifton, M.C, Pizzaro, J.C, Strong, R.K. | 登録日 | 2008-01-15 | 公開日 | 2008-09-09 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.572 Å) | 主引用文献 | The siderocalin/enterobactin interaction: a link between mammalian immunity and bacterial iron transport. J.Am.Chem.Soc., 130, 2008
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3CBC
| Crystal structure of Siderocalin (NGAL, Lipocalin 2) Y106F complexed with Ferric Enterobactin | 分子名称: | 2-(2,3-DIHYDROXY-BENZOYLAMINO)-3-HYDROXY-PROPIONIC ACID, GLYCEROL, Neutrophil gelatinase-associated lipocalin, ... | 著者 | Clifton, M.C, Pizaro, J.C, Strong, R.K. | 登録日 | 2008-02-21 | 公開日 | 2008-09-09 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | The siderocalin/enterobactin interaction: a link between mammalian immunity and bacterial iron transport. J.Am.Chem.Soc., 130, 2008
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6OKE
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4R0L
| Anti-canine CD28 antibody, 1C6, bound canine CD28 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Gewe, M.M, Strong, R.K. | 登録日 | 2014-07-31 | 公開日 | 2015-07-08 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Anti-CD28 Antibody-Initiated Cytokine Storm in Canines. Transplant Direct, 1, 2015
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8CXC
| Novel Anti-Mesothelin Antibodies Enable Crystallography of the Intact Mesothelin Ectodo- main and Engineering of Potent, T cell-engaging Bispecific Therapeutics | 分子名称: | 3F2 Antibody heavy chain, 3F2 Antibody light chain, Mesothelin, ... | 著者 | Bandaranayake, A.D, Rupert, P.B, Lin, I, Pilat, K, Ruff, R.O, Friend, D.J, Chan, M.K, Clarke, M, Carter, J, Meshinchi, S, Mehlin, C, Olson, J.M, Strong, R.K, Correnti, C.E. | 登録日 | 2022-05-20 | 公開日 | 2023-06-07 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (4.31 Å) | 主引用文献 | Novel mesothelin antibodies enable crystallography of the intact mesothelin ectodomain and engineering of potent, T cell-engaging bispecific therapeutics Front. Drug Discov., 3, 2023
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8CYH
| Novel Anti-Mesothelin Antibodies Enable Crystallography of the Intact Mesothelin Ectodo- main and Engineering of Potent, T cell-engaging Bispecific Therapeutics | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, A12 antibody heavy chain, A12 antibody light chain, ... | 著者 | Bandaranayake, A.D, Rupert, P.B, Lin, I, Pilat, K, Ruff, R.O, Friend, D.J, Chan, M.K, Clarke, M, Carter, J, Meshinchi, S, Mehlin, C, Olson, J.M, Strong, R.K, Correnti, C.E. | 登録日 | 2022-05-23 | 公開日 | 2023-06-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.38 Å) | 主引用文献 | Novel mesothelin antibodies enable crystallography of the intact mesothelin ectodomain and engineering of potent, T cell-engaging bispecific therapeutics Front. Drug Discov., 3, 2023
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8CZ8
| Novel Anti-Mesothelin Antibodies Enable Crystallography of the Intact Mesothelin Ectodo- main and Engineering of Potent, T cell-engaging Bispecific Therapeutics | 分子名称: | Mesothelin, cleaved form, SULFATE ION, ... | 著者 | Bandaranayake, A.D, Rupert, P.B, Lin, I, Pilat, K, Ruff, R.O, Friend, D.J, Chan, M.K, Clarke, M, Carter, J, Meshinchi, S, Mehlin, C, Olson, J.M, Strong, R.K, Correnti, C.E. | 登録日 | 2022-05-24 | 公開日 | 2023-06-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Novel mesothelin antibodies enable crystallography of the intact mesothelin ectodomain and engineering of potent, T cell-engaging bispecific therapeutics Front. Drug Discov., 3, 2023
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3CMP
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1L6M
| Neutrophil Gelatinase-associated Lipocalin is a Novel Bacteriostatic Agent that Interferes with Siderophore-mediated Iron Acquisition | 分子名称: | 2,3-DIHYDROXY-BENZOIC ACID, 2-(2,3-DIHYDROXY-BENZOYLAMINO)-3-HYDROXY-PROPIONIC ACID, FE (III) ION, ... | 著者 | Goetz, D.H, Borregaard, N, Bluhm, M.E, Raymond, K.N, Strong, R.K. | 登録日 | 2002-03-11 | 公開日 | 2003-03-11 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The Neutrophil Lipocalin NGAL is a Bacteriostatic Agent that Interferes with Siderophore-mediated Iron Acquisition Mol.Cell, 10, 2002
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5JR8
| Disposal of Iron by a Mutant form of Siderocalin NGAL | 分子名称: | GLYCEROL, Neutrophil gelatinase-associated lipocalin, PHOSPHATE ION | 著者 | Rupert, P.B, Strong, R.K, Barasch, J, Hollman, M, Deng, R, Hod, E.A, Abergel, R, Allred, B, Xu, K, Darrah, S, Tekabe, Y, Perlstein, A, Bruck, E, Stauber, J, Corbin, K, Buchen, C, Slavkovich, V, Graziano, J, Spitalnik, S, Qiu, A. | 登録日 | 2016-05-05 | 公開日 | 2016-09-28 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Disposal of iron by a mutant form of lipocalin 2. Nat Commun, 7, 2016
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5KIC
| Long-sought stabilization of berkelium(IV) in solution: An anomaly within the heavy actinide series | 分子名称: | CALIFORNIUM ION, CHLORIDE ION, N,N'-butane-1,4-diylbis[1-hydroxy-N-(3-{[(1-hydroxy-6-oxo-1,6-dihydropyridin-2-yl)carbonyl]amino}propyl)-6-oxo-1,6-dihydropyridine-2-carboxamide], ... | 著者 | Rupert, P.B, Strong, R.K. | 登録日 | 2016-06-16 | 公開日 | 2017-04-26 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Chelation and stabilization of berkelium in oxidation state +IV. Nat Chem, 9, 2017
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5KID
| Tightening the Recognition of Tetravalent Zr and Th Complexes by the Siderophore-Binding Mammalian Protein Siderocalin for Theranostic Applications | 分子名称: | CHLORIDE ION, GLYCEROL, N,N'-(butane-1,4-diyl)bis(N-{3-[(2,3-dihydroxybenzene-1-carbonyl)amino]propyl}-2,3-dihydroxybenzamide), ... | 著者 | Rupert, P.B, Strong, R.K. | 登録日 | 2016-06-16 | 公開日 | 2017-04-26 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Engineered Recognition of Tetravalent Zirconium and Thorium by Chelator-Protein Systems: Toward Flexible Radiotherapy and Imaging Platforms. Inorg Chem, 55, 2016
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5KHP
| Tightening the Recognition of Tetravalent Zr and Th Complexes by the Siderophore-Binding Mammalian Protein Siderocalin for Theranostic Applications | 分子名称: | GLYCEROL, N,N'-(butane-1,4-diyl)bis(N-{3-[(2,3-dihydroxybenzene-1-carbonyl)amino]propyl}-2,3-dihydroxybenzamide), Neutrophil gelatinase-associated lipocalin, ... | 著者 | Rupert, P.B, Strong, R.K. | 登録日 | 2016-06-15 | 公開日 | 2017-04-26 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Engineered Recognition of Tetravalent Zirconium and Thorium by Chelator-Protein Systems: Toward Flexible Radiotherapy and Imaging Platforms. Inorg Chem, 55, 2016
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1DFV
| CRYSTAL STRUCTURE OF HUMAN NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN MONOMER | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HUMAN NEUTROPHIL GELATINASE, ... | 著者 | Goetz, D.H, Willie, S.T, Armen, R.S, Bratt, T, Borregaard, N, Strong, R.K. | 登録日 | 1999-11-22 | 公開日 | 2000-03-06 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Ligand preference inferred from the structure of neutrophil gelatinase associated lipocalin Biochemistry, 39, 2000
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1QQS
| NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN HOMODIMER | 分子名称: | DECANOIC ACID, NEUTROPHIL GELATINASE, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Goetz, D.H, Willie, S.T, Armen, R, Bratt, T, Borregaard, N, Strong, R.K. | 登録日 | 1999-06-07 | 公開日 | 2000-04-21 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Ligand preference inferred from the structure of neutrophil gelatinase associated lipocalin Biochemistry, 39, 2000
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