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6CU7
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BU of 6cu7 by Molmil
Alpha Synuclein fibril formed by full length protein - Rod Polymorph
分子名称: Alpha-synuclein
著者Li, B, Hatami, A, Ge, P, Murray, K.A, Sheth, P, Zhang, M, Nair, G, Sawaya, M.R, Zhu, C, Broad, M, Shin, W.S, Ye, S, John, V, Eisenberg, D.S, Zhou, Z.H, Jiang, L.
登録日2018-03-23
公開日2018-09-12
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM of full-length alpha-synuclein reveals fibril polymorphs with a common structural kernel.
Nat Commun, 9, 2018
6CU8
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BU of 6cu8 by Molmil
Alpha Synuclein fibril formed by full length protein - Twister Polymorph
分子名称: Alpha-synuclein
著者Li, B, Hatami, A, Ge, P, Murray, K.A, Sheth, P, Zhang, M, Nair, G, Sawaya, M.R, Zhu, C, Broad, M, Shin, W.S, Ye, S, John, V, Eisenberg, D.S, Zhou, Z.H, Jiang, L.
登録日2018-03-23
公開日2018-09-12
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM of full-length alpha-synuclein reveals fibril polymorphs with a common structural kernel.
Nat Commun, 9, 2018
6J60
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BU of 6j60 by Molmil
hnRNP A1 reversible amyloid core GFGGNDNFG (residues 209-217)
分子名称: 9-mer peptide (GFGGNDNFG) from Heterogeneous nuclear ribonucleoprotein A1
著者Luo, F, Zhou, H, Gui, X, Li, D, Li, X, Liu, C.
登録日2019-01-12
公開日2019-04-03
最終更新日2024-03-27
実験手法ELECTRON CRYSTALLOGRAPHY (0.96 Å)
主引用文献Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly.
Nat Commun, 10, 2019
8SKP
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BU of 8skp by Molmil
X-ray structure of the NDM-4 beta-lactamase from Klebsiella pneumonia in complex with 1-hydroxypyridine-2(1H)-thione-6-carboxylic acid
分子名称: 1,2-ETHANEDIOL, 1-hydroxy-6-sulfanylidene-1,6-dihydropyridine-2-carboxylic acid, Metallo-beta-lactamase type 2, ...
著者Thoden, J.B, Holden, H.M.
登録日2023-04-20
公開日2023-08-23
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Characterization of a novel inhibitor for the New Delhi metallo-beta-lactamase-4: Implications for drug design and combating bacterial drug resistance.
J.Biol.Chem., 299, 2023
8SKO
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BU of 8sko by Molmil
X-ray structure of the NDM-4 beta-lactamase from Klebsiella pneumonia with L-Captopril bound
分子名称: L-CAPTOPRIL, Metallo-beta-lactamase type 2, ZINC ION
著者Thoden, J.B, Holden, H.M.
登録日2023-04-20
公開日2023-08-23
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Characterization of a novel inhibitor for the New Delhi metallo-beta-lactamase-4: Implications for drug design and combating bacterial drug resistance.
J.Biol.Chem., 299, 2023
8SK2
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BU of 8sk2 by Molmil
X-ray structure of the NDM-4 beta-lactamase from Klebsiella pneumonia, apo form
分子名称: 1,2-ETHANEDIOL, Metallo-beta-lactamase type 2, ZINC ION
著者Thoden, J.B, Holden, H.M.
登録日2023-04-18
公開日2023-08-23
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Characterization of a novel inhibitor for the New Delhi metallo-beta-lactamase-4: Implications for drug design and combating bacterial drug resistance.
J.Biol.Chem., 299, 2023
7UAK
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BU of 7uak by Molmil
Structure of recombinantly assembled A53E alpha-synuclein fibrils
分子名称: Alpha-synuclein
著者Zhou, K, Zhou, H.
登録日2022-03-13
公開日2023-03-29
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Cryo-EM structure of amyloid fibril formed by alpha-synuclein hereditary A53E mutation reveals a distinct protofilament interface.
J.Biol.Chem., 299, 2023
5Z9R
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BU of 5z9r by Molmil
NMNAT as a specific chaperone antagonizing pathological condensation of phosphorylated tau
分子名称: Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3
著者Dou, S, Ma, X, Li, D, Liu, C.
登録日2018-02-05
公開日2019-02-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Nicotinamide mononucleotide adenylyltransferase uses its NAD+substrate-binding site to chaperone phosphorylated Tau.
Elife, 9, 2020
6BCS
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BU of 6bcs by Molmil
LilrB2 D1D2 domains complexed with benzamidine
分子名称: BENZAMIDINE, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
著者Cao, Q, Sawaya, M.R, Eisenberg, D.S.
登録日2017-10-20
公開日2018-09-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Inhibiting amyloid-beta cytotoxicity through its interaction with the cell surface receptor LilrB2 by structure-based design.
Nat Chem, 10, 2018
5ZGD
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BU of 5zgd by Molmil
hnRNPA1 reversible amyloid core GFGGNDNFG (residues 209-217) determined by X-ray
分子名称: GLY-PHE-GLY-GLY-ASN-ASP-ASN-PHE-GLY
著者Gui, X, Xie, M, Zhao, M, Luo, F, He, J, Li, D, Liu, C.
登録日2018-03-08
公開日2019-04-03
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.401 Å)
主引用文献Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly.
Nat Commun, 10, 2019
5ZGL
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BU of 5zgl by Molmil
hnRNP A1 segment GGGYGGS (residues 234-240)
分子名称: 7-mer peptide from Heterogeneous nuclear ribonucleoprotein A1
著者Xie, M, Luo, F, Gui, X, Zhao, M, He, J, Li, D, Liu, C.
登録日2018-03-09
公開日2019-04-03
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (0.95 Å)
主引用文献Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly.
Nat Commun, 10, 2019

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件を2024-07-24に公開中

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