8SKO
X-ray structure of the NDM-4 beta-lactamase from Klebsiella pneumonia with L-Captopril bound
Summary for 8SKO
Entry DOI | 10.2210/pdb8sko/pdb |
Related | 8sk2 |
Descriptor | Metallo-beta-lactamase type 2, ZINC ION, L-CAPTOPRIL, ... (4 entities in total) |
Functional Keywords | beta-lactamase, antibiotic resistance, metallo-enzyme, hydrolase, hydrolase-inhibitor complex, hydrolase/inhibitor |
Biological source | Klebsiella pneumoniae |
Total number of polymer chains | 2 |
Total formula weight | 49152.64 |
Authors | Thoden, J.B.,Holden, H.M. (deposition date: 2023-04-20, release date: 2023-08-23, Last modification date: 2023-10-04) |
Primary citation | Thoden, J.B.,Benin, B.M.,Priebe, A.,Shin, W.S.,Muthyala, R.,Sham, Y.Y.,Holden, H.M. Characterization of a novel inhibitor for the New Delhi metallo-beta-lactamase-4: Implications for drug design and combating bacterial drug resistance. J.Biol.Chem., 299:105135-105135, 2023 Cited by PubMed: 37549809DOI: 10.1016/j.jbc.2023.105135 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.3 Å) |
Structure validation
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