8SKO
X-ray structure of the NDM-4 beta-lactamase from Klebsiella pneumonia with L-Captopril bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Metallo-beta-lactamase type 2 | polymer | 230 | 24228.2 | 2 | UniProt (C7C422) Pfam (PF00753) | Klebsiella pneumoniae | B2 metallo-beta-lactamase,Beta-lactamase type II,Metallo-beta-lactamase NDM-1,Metallo-beta-lactamase type II,New Delhi metallo-beta-lactamase-1,NDM-1 |
| 2 | C, D, F, G (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | E, H (A, B) | L-CAPTOPRIL | non-polymer | 217.3 | 2 | Chemie (X8Z) | |||
| 4 | I, J (A, B) | water | water | 18.0 | 526 | Chemie (HOH) |
Sequence modifications
A, B: 42 - 270 (UniProt: C7C422)
| PDB | External Database | Details |
|---|---|---|
| Gly 41 | - | expression tag |
| Leu 154 | Met 154 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 48456.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 696.2 | |
| All* | Total formula weight | 49152.6 |
