8SK2

X-ray structure of the NDM-4 beta-lactamase from Klebsiella pneumonia, apo form

Summary for 8SK2

• Entry DOI: 10.2210/pdb8sk2/pdb
• Descriptor: Metallo-beta-lactamase type 2, ZINC ION, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: beta-lactamase, antibiotic resistance, metallo-enzyme, hydrolase
• Biological source: Klebsiella pneumoniae
• Total number of polymer chains: 1
• Total formula weight: 28633.15

Authors

Thoden, J.B.,Holden, H.M. (deposition date: 2023-04-18, release date: 2023-08-23, Last modification date: 2023-10-04)

• Primary citation: Thoden, J.B.,Benin, B.M.,Priebe, A.,Shin, W.S.,Muthyala, R.,Sham, Y.Y.,Holden, H.M.; Characterization of a novel inhibitor for the New Delhi metallo-beta-lactamase-4: Implications for drug design and combating bacterial drug resistance.; J.Biol.Chem., 299:105135-105135, 2023; PubMed: 37549809; DOI: 10.1016/j.jbc.2023.105135

Experimental method

X-RAY DIFFRACTION (1.3 Å)