8FFY
 
 | | Cryo-electron microscopy structure of human mt-SerRS in complex with mt-tRNA(UGA-TL) | | 分子名称: | 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, Serine--tRNA ligase, mitochondrial, ... | | 著者 | Hirschi, M, Kuhle, B, Doerfel, L, Schimmel, P, Lander, G. | | 登録日 | 2022-12-11 | | 公開日 | 2023-08-23 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural basis for a degenerate tRNA identity code and the evolution of bimodal specificity in human mitochondrial tRNA recognition.
Nat Commun, 14, 2023
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7TZB
 | | Crystal structure of the human mitochondrial seryl-tRNA synthetase (mt SerRS) bound with a seryl-adenylate analogue | | 分子名称: | 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, Serine--tRNA ligase, mitochondrial | | 著者 | Kuhle, B, Hirschi, M, Doerfel, L, Lander, G, Schimmel, P. | | 登録日 | 2022-02-15 | | 公開日 | 2022-09-14 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structural basis for shape-selective recognition and aminoacylation of a D-armless human mitochondrial tRNA.
Nat Commun, 13, 2022
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5V59
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3BJU
 | | Crystal Structure of tetrameric form of human lysyl-tRNA synthetase | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, LYSINE, ... | | 著者 | Guo, M, Yang, X.L, Schimmel, P. | | 登録日 | 2007-12-04 | | 公開日 | 2008-02-05 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Crystal structure of tetrameric form of human lysyl-tRNA synthetase: Implications for multisynthetase complex formation
Proc.Natl.Acad.Sci.Usa, 105, 2008
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7U2A
 | | Cryo-electron microscopy structure of human mt-SerRS in complex with mt-tRNA (GCU) | | 分子名称: | 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, RNA (38-MER), Serine--tRNA ligase, ... | | 著者 | Hirschi, M, Kuhle, B, Doerfel, L, Schimmel, P, Lander, G. | | 登録日 | 2022-02-23 | | 公開日 | 2022-09-14 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural basis for shape-selective recognition and aminoacylation of a D-armless human mitochondrial tRNA.
Nat Commun, 13, 2022
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7U2B
 | | Cryo-electron microscopy structure of human mt-SerRS in complex with mt-tRNA(GCU-TL) | | 分子名称: | 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, RNA (53-MER), Serine--tRNA ligase, ... | | 著者 | Hirschi, M, Kuhle, B, Doerfel, L, Schimmel, P, Lander, G. | | 登録日 | 2022-02-23 | | 公開日 | 2022-09-14 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural basis for shape-selective recognition and aminoacylation of a D-armless human mitochondrial tRNA.
Nat Commun, 13, 2022
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4QBT
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4Q93
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6NLY
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6NLQ
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6NOW
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2LW7
 | | NMR solution structure of human HisRS splice variant | | 分子名称: | Histidine--tRNA ligase, cytoplasmic | | 著者 | Ye, F, Wei, Z, Wu, J, Schimmel, P, Zhang, M. | | 登録日 | 2012-07-24 | | 公開日 | 2013-09-04 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR solution structure of human HisRS splice variant
To be Published
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1N3L
 | | Crystal structure of a human aminoacyl-tRNA synthetase cytokine | | 分子名称: | GLYCEROL, SULFATE ION, tyrosyl-tRNA synthetase | | 著者 | Yang, X.-L, Skene, R.J, McRee, D.E, Schimmel, P. | | 登録日 | 2002-10-28 | | 公開日 | 2002-11-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.18 Å) | | 主引用文献 | Crystal structure of a human aminoacyl-tRNA synthetase cytokine
Proc.Natl.Acad.Sci.USA, 99, 2002
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1PYB
 | | Crystal Structure of Aquifex aeolicus Trbp111: a Structure-Specific tRNA Binding Protein | | 分子名称: | tRNA-binding protein Trbp111 | | 著者 | Swairjo, M.A, Morales, A.J, Wang, C.C, Ortiz, A.R, Schimmel, P. | | 登録日 | 2003-07-08 | | 公開日 | 2003-08-05 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of trbp111: a structure-specific tRNA-binding protein.
Embo J., 19, 2000
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3HTZ
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1ILE
 | | ISOLEUCYL-TRNA SYNTHETASE | | 分子名称: | ISOLEUCYL-TRNA SYNTHETASE, ZINC ION | | 著者 | Nureki, O, Vassylyev, D.G, Tateno, M, Shimada, A, Nakama, T, Fukai, S, Konno, M, Schimmel, P, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 1998-02-24 | | 公開日 | 1999-04-13 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Enzyme structure with two catalytic sites for double-sieve selection of substrate.
Science, 280, 1998
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2AZX
 | | Charged and uncharged tRNAs adopt distinct conformations when complexed with human tryptophanyl-tRNA synthetase | | 分子名称: | 72-MER, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Yang, X.L, Otero, F.J, Ewalt, K.L, Liu, J, Swairjo, M.A, Kohrer, C, RajBhandary, U.L, Skene, R.J, McRee, D.E, Schimmel, P. | | 登録日 | 2005-09-12 | | 公開日 | 2006-08-01 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Two conformations of a crystalline human tRNA synthetase-tRNA complex: implications for protein synthesis.
Embo J., 25, 2006
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5T76
 | | A fragment of a human tRNA synthetase | | 分子名称: | Alanine--tRNA ligase, cytoplasmic | | 著者 | Sun, L, Schimmel, P. | | 登録日 | 2016-09-02 | | 公開日 | 2016-11-30 | | 最終更新日 | 2017-01-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Two crystal structures reveal design for repurposing the C-Ala domain of human AlaRS.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5T5S
 | | A fragment of a human tRNA synthetase | | 分子名称: | Alanine--tRNA ligase, cytoplasmic | | 著者 | Sun, L, Schimmel, P. | | 登録日 | 2016-08-31 | | 公開日 | 2016-11-30 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.202 Å) | | 主引用文献 | Two crystal structures reveal design for repurposing the C-Ala domain of human AlaRS.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5V58
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1Q7S
 | | Crystal structure of bit1 | | 分子名称: | bit1 | | 著者 | De Pereda, J.M, Waas, W.F, Jan, Y, Ruoslahti, E, Schimmel, P, Pascual, J. | | 登録日 | 2003-08-19 | | 公開日 | 2003-12-16 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of a human peptidyl-tRNA hydrolase reveals a new fold and suggests basis for a bifunctional activity.
J.Biol.Chem., 279, 2004
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1NTG
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1R6T
 | | crystal structure of human tryptophanyl-tRNA synthetase | | 分子名称: | GLYCEROL, TRYPTOPHANYL-5'AMP, Tryptophanyl-tRNA synthetase | | 著者 | Yang, X.-L, Otero, F.J, Skene, R.J, McRee, D.E, Ribas de Pouplana, L, Schimmel, P. | | 登録日 | 2003-10-16 | | 公開日 | 2004-01-06 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structures that suggest late development of genetic code components for differentiating aromatic side chains
Proc.Natl.Acad.Sci.USA, 100, 2003
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1R6U
 | | Crystal structure of an active fragment of human tryptophanyl-tRNA synthetase with cytokine activity | | 分子名称: | GLYCEROL, TRYPTOPHANYL-5'AMP, Tryptophanyl-tRNA synthetase | | 著者 | Yang, X.-L, Otero, F.J, Skene, R.J, McRee, D.E, Ribas de Pouplana, L, Schimmel, P. | | 登録日 | 2003-10-16 | | 公開日 | 2004-01-06 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Functional and crystal structure analysis of active site adaptations of a potent anti-angiogenic human tRNA synthetase
Structure, 15, 2007
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1RIQ
 | | The crystal structure of the catalytic fragment of the alanyl-tRNA synthetase | | 分子名称: | Alanyl-tRNA synthetase | | 著者 | Swairjo, M.A, Otero, F.J, Yang, X.-L, Lovato, M.A, Skene, R.J, McRee, D.E, Ribas de Pouplana, L, Schimmel, P. | | 登録日 | 2003-11-17 | | 公開日 | 2004-04-06 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Alanyl-tRNA Synthetase Crystal Structure and Design for Acceptor-Stem Recognition
Mol.Cell, 13, 2004
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