Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

5V59

Crystal structure of catalytic fragment of human AlaRS in complex with Aze-SA

Summary for 5V59
Entry DOI10.2210/pdb5v59/pdb
Related5V58
DescriptorAlanine--tRNA ligase, cytoplasmic, 5'-O-{[(2S)-azetidine-2-carbonyl]sulfamoyl}adenosine (3 entities in total)
Functional Keywordsligase, aminoacyl-trna synthetase, non-proteinogenic amino acid
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight53743.60
Authors
Zhou, H.,Song, Y.,Schimmel, P. (deposition date: 2017-03-13, release date: 2018-01-10, Last modification date: 2023-10-04)
Primary citationSong, Y.,Zhou, H.,Vo, M.N.,Shi, Y.,Nawaz, M.H.,Vargas-Rodriguez, O.,Diedrich, J.K.,Yates, J.R.,Kishi, S.,Musier-Forsyth, K.,Schimmel, P.
Double mimicry evades tRNA synthetase editing by toxic vegetable-sourced non-proteinogenic amino acid.
Nat Commun, 8:2281-2281, 2017
Cited by
PubMed: 29273753
DOI: 10.1038/s41467-017-02201-z
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.03 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon