5V59

Crystal structure of catalytic fragment of human AlaRS in complex with Aze-SA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Alanine--tRNA ligase, cytoplasmic	polymer	475	53314.2	1	UniProt (P49588) Pfam (PF01411) In PDB	Homo sapiens (Human)	Alanyl-tRNA synthetase, AlaRS, Renal carcinoma antigen NY-REN-42
2	A	5'-O-{[(2S)-azetidine-2-carbonyl]sulfamoyl}adenosine	non-polymer		429.4	1	Chemie (8X1)
3		water	water		18.0	245	Chemie (HOH)

Sequence modifications

A: 1 - 455 (UniProt: P49588)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	53314.2
Non-Polymers*	Number of molecules	1
	Total formula weight	429.4
All*	Total formula weight	53743.6

*Water molecules are not included.