4QBT
Crystal structure of tyrosine bound human tyrosyl tRNA synthetase
Summary for 4QBT
| Entry DOI | 10.2210/pdb4qbt/pdb |
| Related | 4Q93 |
| Descriptor | Tyrosine--tRNA ligase, cytoplasmic, PHOSPHATE ION, POTASSIUM ION, ... (7 entities in total) |
| Functional Keywords | tyrosine, aminoacyl trna synthetase, rossman fold, aminoacid activation, trna, ester bond, ligase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 42958.11 |
| Authors | Mathew, S.,Schimmel, P. (deposition date: 2014-05-08, release date: 2014-12-17, Last modification date: 2023-09-20) |
| Primary citation | Sajish, M.,Schimmel, P. A human tRNA synthetase is a potent PARP1-activating effector target for resveratrol. Nature, 519:370-373, 2014 Cited by PubMed: 25533949DOI: 10.1038/nature14028 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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