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4QBT

Crystal structure of tyrosine bound human tyrosyl tRNA synthetase

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Tyrosine--tRNA ligase, cytoplasmicpolymer37242133.61UniProt (P54577)
Pfam (PF00579)
Homo sapiens (human)Tyrosyl-tRNA synthetase, TyrRS
2B, H, I
(A)
PHOSPHATE IONnon-polymer95.03Chemie (PO4)
3C, J
(A)
POTASSIUM IONnon-polymer39.12Chemie (K)
4D, E
(A)
GLYCEROLnon-polymer92.12Chemie (GOL)
5F
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
6G
(A)
TYROSINEnon-polymer181.21Chemie (TYR)
7K
(A)
waterwater18.0176Chemie (HOH)
Sequence modifications
A: 1 - 364 (UniProt: P54577)
PDBExternal DatabaseDetails
Leu 365-expression tag
Glu 366-expression tag
His 367-expression tag
His 368-expression tag
His 369-expression tag
His 370-expression tag
His 371-expression tag
His 372-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight42133.6
Non-Polymers*Number of molecules9
Total formula weight824.5
All*Total formula weight42958.1
*Water molecules are not included.

247947

PDB entries from 2026-01-21

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