4QBT

Crystal structure of tyrosine bound human tyrosyl tRNA synthetase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Tyrosine--tRNA ligase, cytoplasmic	polymer	372	42133.6	1	UniProt (P54577) Pfam (PF00579) In PDB	Homo sapiens (human)	Tyrosyl-tRNA synthetase, TyrRS
2	A	PHOSPHATE ION	non-polymer		95.0	3	Chemie (PO4)
3	A	POTASSIUM ION	non-polymer		39.1	2	Chemie (K)
4	A	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
5	A	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
6	A	TYROSINE	non-polymer		181.2	1	Chemie (TYR)
7		water	water		18.0	176	Chemie (HOH)

Sequence modifications

A: 1 - 364 (UniProt: P54577)

PDB	External Database	Details
Leu 365	-	expression tag
Glu 366	-	expression tag
His 367	-	expression tag
His 368	-	expression tag
His 369	-	expression tag
His 370	-	expression tag
His 371	-	expression tag
His 372	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	42133.6
Non-Polymers*	Number of molecules	9
	Total formula weight	824.5
All*	Total formula weight	42958.1

*Water molecules are not included.