1WQ1
 
 | | RAS-RASGAP COMPLEX | | 分子名称: | ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, H-RAS, ... | | 著者 | Scheffzek, K, Ahmadian, M.R, Kabsch, W, Wiesmueller, L, Lautwein, A, Schmitz, F, Wittinghofer, A. | | 登録日 | 1997-07-03 | | 公開日 | 1998-07-15 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants.
Science, 277, 1997
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1WER
 | | RAS-GTPASE-ACTIVATING DOMAIN OF HUMAN P120GAP | | 分子名称: | P120GAP | | 著者 | Scheffzek, K, Lautwein, A, Kabsch, W, Ahmadian, M.R, Wittinghofer, A. | | 登録日 | 1996-11-20 | | 公開日 | 1997-12-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structure of the GTPase-activating domain of human p120GAP and implications for the interaction with Ras.
Nature, 384, 1996
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1NF1
 | | THE GAP RELATED DOMAIN OF NEUROFIBROMIN | | 分子名称: | PROTEIN (NEUROFIBROMIN) | | 著者 | Scheffzek, K, Ahmadian, M.R, Wiesmueller, L, Kabsch, W, Stege, P, Schmitz, F, Wittinghofer, A. | | 登録日 | 1998-07-08 | | 公開日 | 1999-07-20 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural analysis of the GAP-related domain from neurofibromin and its implications.
EMBO J., 17, 1998
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1UKE
 | | UMP/CMP KINASE FROM SLIME MOLD | | 分子名称: | MAGNESIUM ION, P1-(ADENOSINE-5'-P5-(URIDINE-5')PENTAPHOSPHATE, URIDYLMONOPHOSPHATE/CYTIDYLMONOPHOSPHATE KINASE | | 著者 | Scheffzek, K, Kliche, W, Wiesmueller, L, Reinstein, J. | | 登録日 | 1998-01-07 | | 公開日 | 1998-04-29 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of the complex of UMP/CMP kinase from Dictyostelium discoideum and the bisubstrate inhibitor P1-(5'-adenosyl) P5-(5'-uridyl) pentaphosphate (UP5A) and Mg2+ at 2.2 A: implications for water-mediated specificity.
Biochemistry, 35, 1996
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1DS6
 | | CRYSTAL STRUCTURE OF A RAC-RHOGDI COMPLEX | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 2, ... | | 著者 | Scheffzek, K, Stephan, I, Jensen, O.N, Illenberger, D, Gierschik, P. | | 登録日 | 2000-01-07 | | 公開日 | 2000-07-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | The Rac-RhoGDI complex and the structural basis for the regulation of Rho proteins by RhoGDI.
Nat.Struct.Biol., 7, 2000
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1K8R
 | | Crystal structure of Ras-Bry2RBD complex | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Protein kinase byr2, ... | | 著者 | Scheffzek, K, Gruenewald, P, Wohlgemuth, S, Kabsch, W, Tu, H, Wigler, M, Wittinghofer, A, Herrmann, C. | | 登録日 | 2001-10-25 | | 公開日 | 2002-03-13 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | The Ras-Byr2RBD complex: structural basis for Ras effector recognition in yeast.
Structure, 9, 2001
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6EHR
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6EHP
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2FXK
 | | Crystal structure of the macro-domain of human core histone variant macroH2A1.1 (form A) | | 分子名称: | H2A histone family, member Y isoform 1 | | 著者 | Kustatscher, G, Hothorn, M, Pugieux, C, Scheffzek, K, Ladurner, A.G. | | 登録日 | 2006-02-06 | | 公開日 | 2006-02-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | | 主引用文献 | Splicing regulates NAD metabolite binding to histone macroH2A.
Nat.Struct.Mol.Biol., 12, 2005
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3CB5
 | | Crystal Structure of the S. pombe Peptidase Homology Domain of FACT complex subunit Spt16 (form A) | | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FACT complex subunit spt16 | | 著者 | Stuwe, T, Hothorn, M, Lejeune, E, Bortfeld-Miller, M, Scheffzek, K, Ladurner, A.G. | | 登録日 | 2008-02-21 | | 公開日 | 2008-06-17 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | The FACT Spt16 "peptidase" domain is a histone H3-H4 binding module
Proc.Natl.Acad.Sci.USA, 105, 2008
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3P7Z
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1HCI
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1GZS
 | | CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE GEF DOMAIN OF THE SALMONELLA TYPHIMURIUM SOPE TOXIN AND HUMAN Cdc42 | | 分子名称: | GTP-BINDING PROTEIN, SOPE, SULFATE ION | | 著者 | Buchwald, G, Friebel, A, Galan, J.E, Hardt, W.D, Wittinghofer, A, Scheffzek, K. | | 登録日 | 2002-06-05 | | 公開日 | 2002-09-12 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural Basis for the Reversible Activation of a Rho Protein by the Bacterial Toxin Sope
Embo J., 21, 2002
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7R04
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7R03
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1RVD
 | | H-RAS COMPLEXED WITH DIAMINOBENZOPHENONE-BETA,GAMMA-IMIDO-GTP | | 分子名称: | 3-AMINOBENZOPHENONE-4-YL-AMINOHYDROXYPHOSPHINYLAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, TRANSFORMING PROTEIN P21/H-RAS-1 | | 著者 | Ahmadian, M.R, Zor, T, Vogt, D, Kabsch, W, Selinger, Z, Wittinghofer, A, Scheffzek, K. | | 登録日 | 1999-05-03 | | 公開日 | 1999-05-28 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Guanosine triphosphatase stimulation of oncogenic Ras mutants.
Proc.Natl.Acad.Sci.USA, 96, 1999
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3PEG
 | | Crystal structure of Neurofibromins Sec14-PH module containing a patient derived duplication (TD) | | 分子名称: | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, MAGNESIUM ION, Neurofibromin, ... | | 著者 | Welti, S, Kuen, S, D'Angelo, I, Scheffzek, K. | | 登録日 | 2010-10-26 | | 公開日 | 2010-12-08 | | 最終更新日 | 2019-07-17 | | 実験手法 | X-RAY DIFFRACTION (2.524 Å) | | 主引用文献 | Structural and biochemical consequences of NF1 associated nontruncating mutations in the Sec14-PH module of neurofibromin.
Hum.Mutat., 32, 2011
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3PG7
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2PK2
 | | Cyclin box structure of the P-TEFb subunit Cyclin T1 derived from a fusion complex with EIAV Tat | | 分子名称: | Cyclin-T1, Protein Tat | | 著者 | Anand, K, Schulte, A, Fujinaga, K, Scheffzek, K, Geyer, M. | | 登録日 | 2007-04-17 | | 公開日 | 2007-07-03 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | | 主引用文献 | Cyclin Box Structure of the P-TEFb Subunit Cyclin T1 Derived from a Fusion Complex with EIAV Tat.
J.Mol.Biol., 370, 2007
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3IIF
 | | Crystal structure of the macro domain of human histone macroH2A1.1 in complex with ADP-ribose (form B) | | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, Core histone macro-H2A.1, Isoform 1 | | 著者 | Hothorn, M, Bortfeld, M, Ladurner, A.G, Scheffzek, K. | | 登録日 | 2009-07-31 | | 公開日 | 2009-08-18 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation.
Nat.Struct.Mol.Biol., 16, 2009
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3IPR
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3IID
 | | Crystal structure of the macro domain of human histone macroH2A1.1 in complex with ADP-ribose (form A) | | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, Core histone macro-H2A.1, Isoform 1, ... | | 著者 | Hothorn, M, Bortfeld, M, Ladurner, A.G, Scheffzek, K. | | 登録日 | 2009-07-31 | | 公開日 | 2009-08-18 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation.
Nat.Struct.Mol.Biol., 16, 2009
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2QUZ
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3DXB
 | | Structure of the UHM domain of Puf60 fused to thioredoxin | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, thioredoxin N-terminally fused to Puf60(UHM) | | 著者 | Corsini, L, Hothorn, M, Scheffzek, K, Stier, G, Sattler, M. | | 登録日 | 2008-07-24 | | 公開日 | 2008-10-28 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Dimerization and Protein Binding Specificity of the U2AF Homology Motif of the Splicing Factor Puf60.
J.Biol.Chem., 284, 2009
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1CLU
 | | H-RAS COMPLEXED WITH DIAMINOBENZOPHENONE-BETA,GAMMA-IMIDO-GTP | | 分子名称: | 3-AMINOBENZOPHENONE-4-YL-AMINOHYDROXYPHOSPHINYLAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, TRANSFORMING PROTEIN P21/H-RAS-1 | | 著者 | Ahmadian, M.R, Zor, T, Vogt, D, Kabsch, W, Selinger, Z, Wittinghofer, A, Scheffzek, K. | | 登録日 | 1999-05-03 | | 公開日 | 1999-05-28 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Guanosine triphosphatase stimulation of oncogenic Ras mutants.
Proc.Natl.Acad.Sci.USA, 96, 1999
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