3PEG
Crystal structure of Neurofibromins Sec14-PH module containing a patient derived duplication (TD)
Summary for 3PEG
| Entry DOI | 10.2210/pdb3peg/pdb |
| Related | 2e2x |
| Descriptor | Neurofibromin, SULFATE ION, MAGNESIUM ION, ... (5 entities in total) |
| Functional Keywords | sec14 domain, pleckstrin homology domain, ph domain, phosphatidylethanolamin binding, lipid binding, lipid binding protein |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 1 |
| Total formula weight | 34339.48 |
| Authors | Welti, S.,Kuen, S.,D'Angelo, I.,Scheffzek, K. (deposition date: 2010-10-26, release date: 2010-12-08, Last modification date: 2019-07-17) |
| Primary citation | Welti, S.,Kuhn, S.,D'Angelo, I.,Brugger, B.,Kaufmann, D.,Scheffzek, K. Structural and biochemical consequences of NF1 associated nontruncating mutations in the Sec14-PH module of neurofibromin. Hum.Mutat., 32:191-197, 2011 Cited by PubMed: 21089070DOI: 10.1002/humu.21405 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.524 Å) |
Structure validation
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