3PEG
Crystal structure of Neurofibromins Sec14-PH module containing a patient derived duplication (TD)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Neurofibromin | polymer | 290 | 33114.9 | 1 | UniProt (P21359) Pfam (PF13716) Pfam (PF21877) | Homo sapiens (human) | Neurofibromatosis-related protein NF-1, Neurofibromin truncated |
| 2 | B, C, D, E, F (A) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 3 | G (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | H (A) | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE | non-polymer | 720.0 | 1 | Chemie (PEV) | |||
| 5 | I (A) | water | water | 18.0 | 15 | Chemie (HOH) |
Sequence modifications
A: 1545 - 1712 (UniProt: P21359)
A: 1699 - 1712 (UniProt: P21359)
A: 1713 - 1816 (UniProt: P21359)
| PDB | External Database | Details |
|---|---|---|
| Gly 1541 | - | expression tag |
| Ala 1542 | - | expression tag |
| Met 1543 | - | expression tag |
| Gly 1544 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 1699 | Glu 1720 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33114.9 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1224.6 | |
| All* | Total formula weight | 34339.5 |
