7R04
Neurofibromin in open conformation
Summary for 7R04
Entry DOI | 10.2210/pdb7r04/pdb |
Related | 7R03 |
EMDB information | 14219 |
Descriptor | Isoform I of Neurofibromin, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE (2 entities in total) |
Functional Keywords | signalling protein, homodimer, neurofibromatosis, gap, signaling protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 635360.87 |
Authors | Chaker-Margot, M.,Scheffzek, K.,Maier, T. (deposition date: 2022-02-01, release date: 2022-03-30, Last modification date: 2022-04-20) |
Primary citation | Chaker-Margot, M.,Werten, S.,Dunzendorfer-Matt, T.,Lechner, S.,Ruepp, A.,Scheffzek, K.,Maier, T. Structural basis of activation of the tumor suppressor protein neurofibromin. Mol.Cell, 82:1288-, 2022 Cited by PubMed: 35353986DOI: 10.1016/j.molcel.2022.03.011 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.7 Å) |
Structure validation
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