1NF1

THE GAP RELATED DOMAIN OF NEUROFIBROMIN

Summary for 1NF1

Entry DOI	10.2210/pdb1nf1/pdb
Descriptor	PROTEIN (NEUROFIBROMIN) (1 entity in total)
Functional Keywords	neurofibromin, type i neurofibromatosis, nf1, ras, gap, signal transduction, cancer, growth regulation, gtp hydrolysis, patient mutation, arginine finger, signaling protein
Biological source	Homo sapiens (human)
Cellular location	Nucleus : P21359
Total number of polymer chains	1
Total formula weight	37982.67
Authors	Scheffzek, K.,Ahmadian, M.R.,Wiesmueller, L.,Kabsch, W.,Stege, P.,Schmitz, F.,Wittinghofer, A. (deposition date: 1998-07-08, release date: 1999-07-20, Last modification date: 2023-12-27)
Primary citation	Scheffzek, K.,Ahmadian, M.R.,Wiesmuller, L.,Kabsch, W.,Stege, P.,Schmitz, F.,Wittinghofer, A. Structural analysis of the GAP-related domain from neurofibromin and its implications. EMBO J., 17:4313-4327, 1998 Cited by PubMed: 9687500 DOI: 10.1093/emboj/17.15.4313 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation