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6XTX
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BU of 6xtx by Molmil
CryoEM structure of human CMG bound to ATPgammaS and DNA
分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45 homolog, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), ...
著者Rzechorzek, N.J, Pellegrini, L.
登録日2020-01-16
公開日2020-05-27
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献CryoEM structures of human CMG-ATP gamma S-DNA and CMG-AND-1 complexes.
Nucleic Acids Res., 48, 2020
6XTY
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BU of 6xty by Molmil
CryoEM structure of human CMG bound to AND-1 (CMGA)
分子名称: Cell division control protein 45 homolog, DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, ...
著者Rzechorzek, N.J, Pellegrini, L, Chirgadze, D.Y, Hardwick, S.W.
登録日2020-01-16
公開日2020-05-27
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (6.77 Å)
主引用文献CryoEM structures of human CMG-ATP gamma S-DNA and CMG-AND-1 complexes.
Nucleic Acids Res., 48, 2020
8QHQ
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BU of 8qhq by Molmil
Crystal structure of human DNPH1 bound to hmdUMP
分子名称: 1,2-ETHANEDIOL, 2'-deoxynucleoside 5'-phosphate N-hydrolase 1, 5-HYDROXYMETHYLURIDINE-2'-DEOXY-5'-MONOPHOSPHATE
著者Rzechorzek, N.J, West, S.C.
登録日2023-09-09
公開日2023-11-08
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Mechanism of substrate hydrolysis by the human nucleotide pool sanitiser DNPH1.
Nat Commun, 14, 2023
8QHR
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BU of 8qhr by Molmil
Crystal structure of the human DNPH1 glycosyl-enzyme intermediate
分子名称: 1',2'-DIDEOXYRIBOFURANOSE-5'-PHOSPHATE, 1,2-ETHANEDIOL, 2'-deoxynucleoside 5'-phosphate N-hydrolase 1, ...
著者Rzechorzek, N.J, West, S.C.
登録日2023-09-09
公開日2023-11-08
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Mechanism of substrate hydrolysis by the human nucleotide pool sanitiser DNPH1.
Nat Commun, 14, 2023
4D2I
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BU of 4d2i by Molmil
Crystal structure of the HerA hexameric DNA translocase from Sulfolobus solfataricus bound to AMP-PNP
分子名称: HERA, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Rzechorzek, N.J, Blackwood, J.K, Bray, S.M, Maman, J.D, Pellegrini, L, Robinson, N.P.
登録日2014-05-09
公開日2014-12-03
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.841 Å)
主引用文献Structure of the Hexameric Hera ATPase Reveals a Mechanism of Translocation-Coupled DNA-End Processing in Archaea
Nat.Commun., 5, 2014
2YGK
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BU of 2ygk by Molmil
Crystal structure of the NurA nuclease from Sulfolobus solfataricus
分子名称: MANGANESE (II) ION, NURA
著者Rzechorzek, N.J, Blackwood, J.K, Abrams, A.S, Maman, J.D, Robinson, N.P, Pellegrini, L.
登録日2011-04-18
公開日2011-12-14
最終更新日2012-04-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and Functional Insights Into DNA-End Processing by the Archaeal Hera Helicase-Nura Nuclease Complex.
Nucleic Acids Res., 40, 2012
3G65
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BU of 3g65 by Molmil
Crystal Structure of the Human Rad9-Rad1-Hus1 DNA Damage Checkpoint Complex
分子名称: Cell cycle checkpoint control protein RAD9A, Cell cycle checkpoint protein RAD1, Checkpoint protein HUS1
著者Dore, A.S, Kilkenny, M.L, Rzechorzek, N.J, Pearl, L.H.
登録日2009-02-06
公開日2009-05-26
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of the rad9-rad1-hus1 DNA damage checkpoint complex--implications for clamp loading and regulation.
Mol.Cell, 34, 2009
2BZB
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BU of 2bzb by Molmil
NMR Solution Structure of a protein aspartic acid phosphate phosphatase from Bacillus Anthracis
分子名称: CONSERVED DOMAIN PROTEIN
著者Grenha, R, Rzechorzek, N.J, Brannigan, J.A, Ab, E, Folkers, G.E, De Jong, R.N, Diercks, T, Wilkinson, A.J, Kaptein, R, Wilson, K.S.
登録日2005-08-14
公開日2006-09-25
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural characterization of Spo0E-like protein-aspartic acid phosphatases that regulate sporulation in bacilli.
J. Biol. Chem., 281, 2006
2C0S
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BU of 2c0s by Molmil
NMR Solution Structure of a protein aspartic acid phosphate phosphatase from Bacillus Anthracis
分子名称: CONSERVED DOMAIN PROTEIN
著者Grenha, R, Rzechorzek, N.J, Brannigan, J.A, Ab, E, Folkers, G.E, De Jong, R.N, Diercks, T, Wilkinson, A.J, Kaptein, R, Wilson, K.S.
登録日2005-09-07
公開日2006-09-25
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural characterization of Spo0E-like protein-aspartic acid phosphatases that regulate sporulation in bacilli.
J. Biol. Chem., 281, 2006
2XCD
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BU of 2xcd by Molmil
Structure of YncF,the genomic dUTPase from Bacillus subtilis
分子名称: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ...
著者Garcia, J, Burchell, L, Takezawa, M, Rzechorzek, N.J, Fogg, M, Wilson, K.S.
登録日2010-04-22
公開日2010-08-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献The Structure of the Genomic Bacillus Subtilis Dutpase: Novel Features in the Phe-Lid.
Acta Crystallogr.,Sect.D, 66, 2010
7OPL
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BU of 7opl by Molmil
CryoEM structure of DNA Polymerase alpha - primase bound to SARS CoV nsp1
分子名称: DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase large subunit, ...
著者Kilkenny, M.L, Pellegrini, L.
登録日2021-06-01
公開日2021-11-10
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (4.12 Å)
主引用文献Structural basis for the interaction of SARS-CoV-2 virulence factor nsp1 with DNA polymerase alpha-primase.
Protein Sci., 31, 2022
6R4S
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BU of 6r4s by Molmil
Crystal structure of the Pri1 subunit of human primase bound to ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA primase small subunit, MANGANESE (II) ION, ...
著者Kilkenny, M.L, Pellegrini, L.
登録日2019-03-24
公開日2019-09-11
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine.
Acs Chem.Biol., 14, 2019
6R4T
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BU of 6r4t by Molmil
Crystal structure of the Pri1 subunit of human primase bound to vidarabine triphosphate
分子名称: 1,2-ETHANEDIOL, 9-{5-O-[(S)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-arabinofuranosyl}-9H-purin-6-amine, DNA primase small subunit, ...
著者Kilkenny, M.L, Pellegrini, L.
登録日2019-03-24
公開日2019-09-11
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine.
Acs Chem.Biol., 14, 2019
6R5E
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BU of 6r5e by Molmil
Crystal structure of the Pri1 subunit of human primase bound to 2F-ATP
分子名称: 1,2-ETHANEDIOL, 2-fluoro-ATP, DNA primase small subunit, ...
著者Kilkenny, M.L, Pellegrini, L.
登録日2019-03-24
公開日2019-09-11
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine.
Acs Chem.Biol., 14, 2019
6RB4
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BU of 6rb4 by Molmil
Crystal structure of the Pri1 subunit of human primase
分子名称: 1,2-ETHANEDIOL, DNA primase small subunit, ZINC ION
著者Kilkenny, M.L, Pellegrini, L.
登録日2019-04-09
公開日2019-09-11
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine.
Acs Chem.Biol., 14, 2019
6R5D
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BU of 6r5d by Molmil
Crystal structure of the Pri1 subunit of human primase bound to dATP
分子名称: 1,2-ETHANEDIOL, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA primase small subunit, ...
著者Kilkenny, M.L, Pellegrini, L.
登録日2019-03-24
公開日2019-09-11
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine.
Acs Chem.Biol., 14, 2019
6R4U
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BU of 6r4u by Molmil
Crystal structure of the Pri1 subunit of human primase bound to fludarabine triphosphate
分子名称: 1,2-ETHANEDIOL, 2-fluoro-9-{5-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-arabinofuranosyl}-9H-purin-6-a mine, DNA primase small subunit, ...
著者Kilkenny, M.L, Pellegrini, L.
登録日2019-03-24
公開日2019-09-11
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine.
Acs Chem.Biol., 14, 2019
7BGF
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BU of 7bgf by Molmil
CRYSTAL STRUCTURE OF THE N-TERMINAL DIMERIC COILED COIL OF THE HUMAN CTIP PROTEIN
分子名称: DNA endonuclease RBBP8,CtIP/RBBP8
著者Morton, C.R, Pellegrini, L.
登録日2021-01-07
公開日2021-06-30
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.802 Å)
主引用文献Structural basis for the coiled-coil architecture of human CtIP.
Open Biology, 11, 2021
4D2H
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BU of 4d2h by Molmil
Crystal structure of the tetramerisation domain of human CtIP
分子名称: RBBP8, SULFATE ION
著者Davies, O.R, Sun, M, Pellegrini, L.
登録日2014-05-09
公開日2015-01-14
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Ctip Tetramer Assembly is Required for DNA-End Resection and Repair.
Nat.Struct.Mol.Biol., 22, 2015

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