7OPL
CryoEM structure of DNA Polymerase alpha - primase bound to SARS CoV nsp1
Summary for 7OPL
| Entry DOI | 10.2210/pdb7opl/pdb |
| EMDB information | 13020 |
| Descriptor | DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase small subunit, ... (7 entities in total) |
| Functional Keywords | dna polymerase, primase, viral protein, dna binding protein |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 5 |
| Total formula weight | 308543.43 |
| Authors | Kilkenny, M.L.,Pellegrini, L. (deposition date: 2021-06-01, release date: 2021-11-10, Last modification date: 2024-07-17) |
| Primary citation | Kilkenny, M.L.,Veale, C.E.,Guppy, A.,Hardwick, S.W.,Chirgadze, D.Y.,Rzechorzek, N.J.,Maman, J.D.,Pellegrini, L. Structural basis for the interaction of SARS-CoV-2 virulence factor nsp1 with DNA polymerase alpha-primase. Protein Sci., 31:333-344, 2022 Cited by PubMed: 34719824DOI: 10.1002/pro.4220 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (4.12 Å) |
Structure validation
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