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7TL0
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BU of 7tl0 by Molmil
Cryo-EM structure of hMPV preF bound by Fabs MPE8 and SAN32-2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, ...
著者Rush, S.A, Hsieh, C.-L, McLellan, J.S.
登録日2022-01-17
公開日2022-09-14
最終更新日2022-11-23
実験手法ELECTRON MICROSCOPY (3.06 Å)
主引用文献Characterization of prefusion-F-specific antibodies elicited by natural infection with human metapneumovirus.
Cell Rep, 40, 2022
8TW3
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BU of 8tw3 by Molmil
hMPV fusion protein complexed with single domain antibodies sdHMPV16 and sdHMPV12
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein, Single domain antibody sdHMPV12, ...
著者Rush, S.A, McLellan, J.S.
登録日2023-08-19
公開日2024-01-24
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A neutralizing single-domain antibody that targets the trimer interface of the human metapneumovirus fusion protein.
Mbio, 15, 2024
7UR4
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BU of 7ur4 by Molmil
Cryo-EM Structure of the Neutralizing Antibody MPV467 in Complex with Prefusion Human Metapneumovirus F Glycoprotein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, MPV467 Fab Heavy chain, ...
著者Rush, S.A, McLellan, J.S.
登録日2022-04-21
公開日2022-06-08
最終更新日2022-06-29
実験手法ELECTRON MICROSCOPY (3.34 Å)
主引用文献Structural basis for ultrapotent antibody-mediated neutralization of human metapneumovirus.
Proc.Natl.Acad.Sci.USA, 119, 2022
7SEM
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BU of 7sem by Molmil
Structure-based design of prefusion-stabilized human metapneumovirus fusion proteins
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, MPE8 Fab heavy chain, ...
著者Rush, S.A, Hsieh, C.-L, McLellan, J.S.
登録日2021-09-30
公開日2022-02-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure-based design of prefusion-stabilized human metapneumovirus fusion proteins.
Nat Commun, 13, 2022
7TJQ
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BU of 7tjq by Molmil
SAN27-14 bound to a antigenic site V on prefusion-stabilized hMPV F
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, MPE8 Fab heavy chain, ...
著者Hsieh, C.-L, McLellan, J.S, Rush, S.A.
登録日2022-01-16
公開日2022-09-14
最終更新日2022-11-23
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Characterization of prefusion-F-specific antibodies elicited by natural infection with human metapneumovirus.
Cell Rep, 40, 2022
7LUD
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BU of 7lud by Molmil
Crystal structure of Fab ADI-14442
分子名称: ADI-14442 Fab Heavy chain, ADI-14442 Fab Light chain, SULFATE ION
著者Rush, S.A, McLellan, J.S.
登録日2021-02-22
公開日2021-06-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses.
Immunity, 54, 2021
7SEJ
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BU of 7sej by Molmil
Structure-based design of prefusion-stabilized human metapneumovirus fusion proteins
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F1 subunit, Fusion glycoprotein F2 subunit
著者Hsieh, C.-L, Rush, S.A, McLellan, J.S.
登録日2021-09-30
公開日2022-02-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structure-based design of prefusion-stabilized human metapneumovirus fusion proteins.
Nat Commun, 13, 2022
8CW9
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BU of 8cw9 by Molmil
Prefusion-stabilized hMPV fusion protein bound to ADI-61026 and MPE8 Fabs
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADI-61026 heavy, ADI-61026 light, ...
著者Hsieh, C.-L, McLellan, J.S.
登録日2022-05-18
公開日2022-08-10
最終更新日2023-02-22
実験手法ELECTRON MICROSCOPY (3.46 Å)
主引用文献Potently neutralizing and protective anti-human metapneumovirus antibodies target diverse sites on the fusion glycoprotein.
Immunity, 55, 2022
6U7N
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BU of 6u7n by Molmil
Crystal structure of neurotrimin (NTM)
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Neurotrimin, ...
著者Machius, M, Venkannagari, H, Misra, A, Rudenko, G, Rush, S.
登録日2019-09-03
公開日2020-08-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.321 Å)
主引用文献Highly Conserved Molecular Features in IgLONs Contrast Their Distinct Structural and Biological Outcomes.
J.Mol.Biol., 432, 2020
7LUE
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BU of 7lue by Molmil
Prefusion RSV F glycoprotein bound by neutralizing site V-directed antibody ADI-14442
分子名称: Fusion glycoprotein F0, Heavy chain of human antibody Fab ADI-14442, Light chain of human antibody Fab ADI-14442
著者Gilman, M.S.A, McLellan, J.S.
登録日2021-02-22
公開日2021-06-16
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses.
Immunity, 54, 2021
7LUC
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BU of 7luc by Molmil
Cryo-EM structure of RSV preF bound by Fabs 32.4K and 01.4B
分子名称: 01.4B Fab Heavy chain, 01.4B Fab Light chain, 32.4K Fab Heavy chain, ...
著者Wrapp, D, McLellan, J.S.
登録日2021-02-22
公開日2021-04-21
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (3.21 Å)
主引用文献Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses.
Immunity, 54, 2021
6U6T
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BU of 6u6t by Molmil
Neuronal growth regulator 1 (NEGR1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neuronal growth regulator 1, ...
著者Machius, M, Venkannagari, H, Misra, A, Rudenko, G.
登録日2019-08-30
公開日2020-08-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Highly Conserved Molecular Features in IgLONs Contrast Their Distinct Structural and Biological Outcomes.
J.Mol.Biol., 432, 2020

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件を2024-07-10に公開中

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