4U3X
 
 | | Structure of a human VH antibody domain binding to the cleft of hen egg lysozyme | | 分子名称: | 1,2-ETHANEDIOL, Human VH domain antibody, Lysozyme C | | 著者 | Rouet, R, Langley, D.B, Christ, D. | | 登録日 | 2014-07-23 | | 公開日 | 2015-03-11 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Fully Human VH Single Domains That Rival the Stability and Cleft Recognition of Camelid Antibodies
J.Biol.Chem., 290, 2015
|
|
6DSI
 | |
7T5O
 | | VFLIP Spike Trimer with GAR03 | | 分子名称: | GAR03 Fab heavy chain, GAR03 Fab light chain, Spike glycoprotein | | 著者 | Sobti, M, Stewart, A.G, Rouet, R, Langley, D.B. | | 登録日 | 2021-12-12 | | 公開日 | 2023-01-25 | | 最終更新日 | 2023-08-09 | | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | | 主引用文献 | Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients.
Nat Commun, 14, 2023
|
|
7T72
 | | Epitope-based selection of SARS-CoV-2 neutralizing antibodies from convalescent patients | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody heavy chain, Antibody light chain, ... | | 著者 | Langley, D.B, Christ, D, Rouet, R. | | 登録日 | 2021-12-14 | | 公開日 | 2022-12-21 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (3.177 Å) | | 主引用文献 | Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients.
Nat Commun, 14, 2023
|
|
4N1C
 | | Structural evidence for antigen receptor evolution | | 分子名称: | Lysozyme C, immunoglobulin variable light chain domain | | 著者 | Langley, D.B, Rouet, R, Roome, B, Stock, D, Christ, D. | | 登録日 | 2013-10-03 | | 公開日 | 2014-10-29 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural reconstruction of protein ancestry.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
4N1E
 | | Structural evidence for antigen receptor evolution | | 分子名称: | Lysozyme C, immunoglobulin variable light chain domain | | 著者 | Langley, D.B, Rouet, R, Stock, D, Christ, D. | | 登録日 | 2013-10-04 | | 公開日 | 2014-10-29 | | 最終更新日 | 2018-04-18 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Structural reconstruction of protein ancestry.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
4PGJ
 | |
4X4Z
 | |
3UPC
 | | A general strategy for the generation of human antibody variable domains with increased aggregation resistance | | 分子名称: | DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, TETRAETHYLENE GLYCOL, ... | | 著者 | Dudgeon, K, Rouet, R, Kokmeijer, I, Langley, D.B, Christ, D. | | 登録日 | 2011-11-17 | | 公開日 | 2012-06-20 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | General strategy for the generation of human antibody variable domains with increased aggregation resistance
Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
3UPA
 | | A general strategy for the generation of human antibody variable domains with increased aggregation resistance | | 分子名称: | kappa light chain variable domain | | 著者 | Dudgeon, K, Rouet, R, Kokmeijer, I, Langley, D.B, Christ, D. | | 登録日 | 2011-11-17 | | 公開日 | 2012-06-20 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | General strategy for the generation of human antibody variable domains with increased aggregation resistance
Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
4QXT
 | | Crystal Structure of anti-MSP2 Fv fragment (mAb6D8)in complex with FC27-MSP2 14-30 | | 分子名称: | Fv fragment(mAb6D8) heavy chain, Fv fragment(mAb6D8) light chain, Merozoite surface antigen 2 | | 著者 | Morales, R.A.V, MacRaild, C.A, Seow, J, Bankala, K, Drinkwater, N, McGowan, S, Rouet, R, Christ, D, Anders, R.F, Norton, R.S. | | 登録日 | 2014-07-22 | | 公開日 | 2015-06-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate.
Sci Rep, 5, 2015
|
|
4QY8
 | | Crystal Structure of anti-MSP2 Fv fragment (mAb6D8) in complex with 3D7-MSP2 14-30 | | 分子名称: | Fv fragment(mAb6D8) heavy chain, Fv fragment(mAb6D8) light chain, Merozoite surface antigen 2 | | 著者 | Morales, R.A.V, MacRaild, C.A, Seow, J, Bankala, K, Drinkwater, N, McGowan, S, Rouet, R, Christ, D, Anders, R.F, Norton, R.S. | | 登録日 | 2014-07-24 | | 公開日 | 2015-06-03 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.353 Å) | | 主引用文献 | Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate.
Sci Rep, 5, 2015
|
|
4QYO
 | | Crystal Structure of anti-MSP2 Fv fragment (mAb6D8)in complex with MSP2 14-22 | | 分子名称: | Fv fragment(mAb6D8) heavy chain, Fv fragment(mAb6D8) light chain, Merozoite surface antigen 2 | | 著者 | Morales, R.A.V, MacRaild, C.A, Seow, J, Bankala, K, Drinkwater, N, McGowan, S, Rouet, R, Christ, D, Anders, R.F, Norton, R.S. | | 登録日 | 2014-07-24 | | 公開日 | 2015-06-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.208 Å) | | 主引用文献 | Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate.
Sci Rep, 5, 2015
|
|
4R3S
 | | Crystal Structure of anti-MSP2 Fv fragment (mAb6D8)in complex with MSP2 11-23 | | 分子名称: | FV FRAGMENT(MAB6D8) HEAVY CHAIN, FV FRAGMENT(MAB6D8) LIGHT CHAIN, Merozoite surface protein | | 著者 | Morales, R.A.V, MacRaild, C.A, Seow, J, Bankala, K, Drinkwater, N, McGowan, S, Rouet, R, Christ, D, Anders, R.F, Norton, R.S. | | 登録日 | 2014-08-18 | | 公開日 | 2015-06-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate
Sci Rep, 5, 2015
|
|
8DXU
 | |
8DXT
 | | Fab arm of antibody GAR12 bound to the receptor binding domain of SARS-CoV-2. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab arm of antibody GAR12, Light chain of Fab arm of antibody GAR12, ... | | 著者 | Langley, D.B, Christ, D, Henry, J.Y. | | 登録日 | 2022-08-03 | | 公開日 | 2023-01-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients.
Nat Commun, 14, 2023
|
|
7KZB
 | |
7KZC
 | |
7KZA
 | |
7MSQ
 | |
6DN0
 | |
6MH2
 | | Structure of Herceptin Fab without antigen | | 分子名称: | Herceptin Fab arm heavy chain, Herceptin Fab arm light chain | | 著者 | Luthra, A, Langley, D.B, Christie, M, Christ, D. | | 登録日 | 2018-09-17 | | 公開日 | 2019-05-29 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Human Antibody Bispecifics through Phage Display Selection.
Biochemistry, 58, 2019
|
|
5TBD
 | | Crystal Structure of anti-MSP2 Fv fragment (mAb4D11) in complex with 3D7-MSP2 215-222 | | 分子名称: | Fv fragment (mAb4D1) heavy chain, Merozoite surface protein 2 | | 著者 | Seow, J, Morales, R.A.V, MacRaild, C.A, Bankala, K, Drinkwater, N, Dingjan, T, Jaipuria, G, Wilde, K, Anders, R.F, Atreya, H.S, Christ, D, McGowan, S, Norton, R.S. | | 登録日 | 2016-09-12 | | 公開日 | 2017-02-15 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure and Characterisation of a Key Epitope in the Conserved C-Terminal Domain of the Malaria Vaccine Candidate MSP2.
J. Mol. Biol., 429, 2017
|
|
6BFT
 | |
6BGT
 | |
