4X4Z

Retrofitting antibodies with stabilizing mutations. Herceptin VL mutant F53D.

Summary for 4X4Z

• Entry DOI: 10.2210/pdb4x4z/pdb
• Related: 4X4X 4X4Y
• Descriptor: Herceptin VL domain with F53D mutation (2 entities in total)
• Functional Keywords: antibody stabilization mutations, immune system
• Biological source: Homo sapiens
• Total number of polymer chains: 2
• Total formula weight: 23347.85

Authors

Langley, D.B.,Rouet, R.,Christ, D. (deposition date: 2014-12-04, release date: 2015-12-23)

• Primary citation: Langley, D.B.,Rouet, R.,Christ, D.; Retrofitting antibodies with stabilizing mutations; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)