7D5Q
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![BU of 7d5q by Molmil](/molmil-images/mine/7d5q) | Structure of NorC transporter (K398A mutant) in an outward-open conformation in complex with a single-chain Indian camelid antibody | 分子名称: | Drug transporter, putative, ICab, ... | 著者 | Kumar, S, Athreya, A, Penmatsa, A. | 登録日 | 2020-09-27 | 公開日 | 2021-06-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Structural basis of inhibition of a transporter from Staphylococcus aureus, NorC, through a single-domain camelid antibody. Commun Biol, 4, 2021
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7D5P
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![BU of 7d5p by Molmil](/molmil-images/mine/7d5p) | Structure of NorC transporter in an outward-open conformation in complex with a single-chain Indian camelid antibody | 分子名称: | Drug transporter, putative, ICab, ... | 著者 | Kumar, S, Athreya, A, Penmatsa, A. | 登録日 | 2020-09-27 | 公開日 | 2021-06-09 | 最終更新日 | 2021-07-14 | 実験手法 | X-RAY DIFFRACTION (3.65 Å) | 主引用文献 | Structural basis of inhibition of a transporter from Staphylococcus aureus, NorC, through a single-domain camelid antibody. Commun Biol, 4, 2021
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6KSN
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![BU of 6ksn by Molmil](/molmil-images/mine/6ksn) | Structure of a Zn-bound camelid single domain antibody | 分子名称: | 1,2-ETHANEDIOL, ICab3, SODIUM ION, ... | 著者 | Kumar, S, Athreya, A, Penmatsa, A. | 登録日 | 2019-08-24 | 公開日 | 2019-11-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Isolation and structural characterization of a Zn2+-bound single-domain antibody against NorC, a putative multidrug efflux transporter in bacteria. J.Biol.Chem., 295, 2020
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2XBZ
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![BU of 2xbz by Molmil](/molmil-images/mine/2xbz) | Multiple oligomeric forms of the Pseudomonas aeruginosa RetS sensor domain modulate accessibility to the ligand-binding site | 分子名称: | RETS-HYBRID SENSOR KINASE | 著者 | Vincent, F, Round, A, Reynaud, A, Bordi, C, Filloux, A, Bourne, Y. | 登録日 | 2010-04-15 | 公開日 | 2010-06-30 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Distinct Oligomeric Forms of the Pseudomonas Aeruginosa Rets Sensor Domain Modulate Accessibility to the Ligand Binding Site. Environ.Microbiol., 12, 2010
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6BP2
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![BU of 6bp2 by Molmil](/molmil-images/mine/6bp2) | Therapeutic human monoclonal antibody MR191 bound to a marburgvirus glycoprotein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein, Envelope glycoprotein GP2, ... | 著者 | King, L.B, Fusco, M.L, Flyak, A.I, Ilinykh, P.A, Huang, K, Gunn, B, Kirchdoerfer, R.N, Hastie, K.M, Sangha, A.K, Meiler, J, Alter, G, Bukreyev, A, Crowe, J.E.J, Saphire, E.O. | 登録日 | 2017-11-21 | 公開日 | 2018-01-17 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.172 Å) | 主引用文献 | The Marburgvirus-Neutralizing Human Monoclonal Antibody MR191 Targets a Conserved Site to Block Virus Receptor Binding. Cell Host Microbe, 23, 2018
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7ZV3
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![BU of 7zv3 by Molmil](/molmil-images/mine/7zv3) | Crystal structure of indoleamine 2,3-dioxygenase 1 (IDO1) in complex with ferric heme and MMG-0472 | 分子名称: | 4-(3-chloro-2-phenethylphenyl)-1H-1,2,3-triazole, GLYCEROL, Indoleamine 2,3-dioxygenase 1, ... | 著者 | Roehrig, U.F, Reynaud, A, Pojer, F, Michielin, O, Zoete, V. | 登録日 | 2022-05-13 | 公開日 | 2022-07-06 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.551 Å) | 主引用文献 | Structure-based optimization of type III indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors. J Enzyme Inhib Med Chem, 37, 2022
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4EV6
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![BU of 4ev6 by Molmil](/molmil-images/mine/4ev6) | The complete structure of CorA magnesium transporter from Methanocaldococcus jannaschii | 分子名称: | MAGNESIUM ION, Magnesium transport protein CorA, UNDECYL-MALTOSIDE | 著者 | Guskov, A, Nordin, N, Reynaud, A, Engman, H, Lundback, A.-K, Jong, A.J.O, Cornvik, T, Phua, T, Eshaghi, S. | 登録日 | 2012-04-25 | 公開日 | 2012-10-31 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural insights into the mechanisms of Mg2+ uptake, transport, and gating by CorA Proc.Natl.Acad.Sci.USA, 109, 2012
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1ZVI
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![BU of 1zvi by Molmil](/molmil-images/mine/1zvi) | Rat Neuronal Nitric Oxide Synthase Oxygenase Domain | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, Nitric-oxide synthase, brain, ... | 著者 | Matter, H, Kumar, H.S, Fedorov, R, Frey, A, Kotsonis, P, Hartmann, E, Frohlich, L.G, Reif, A, Pfleiderer, W, Scheurer, P, Ghosh, D.K, Schlichting, I, Schmidt, H.H. | 登録日 | 2005-06-02 | 公開日 | 2005-08-02 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural Analysis of Isoform-Specific Inhibitors Targeting the Tetrahydrobiopterin Binding Site of Human Nitric Oxide Synthases. J.Med.Chem., 48, 2005
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1ZVL
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![BU of 1zvl by Molmil](/molmil-images/mine/1zvl) | Rat Neuronal Nitric Oxide Synthase Oxygenase Domain complexed with natural substrate L-Arg. | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ARGININE, Nitric-oxide synthase, ... | 著者 | Matter, H, Kumar, H.S, Fedorov, R, Frey, A, Kotsonis, P, Hartmann, E, Frohlich, L.G, Reif, A, Pfleiderer, W, Scheurer, P, Ghosh, D.K, Schlichting, I, Schmidt, H.H. | 登録日 | 2005-06-02 | 公開日 | 2005-08-02 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural Analysis of Isoform-Specific Inhibitors Targeting the Tetrahydrobiopterin Binding Site of Human Nitric Oxide Synthases. J.Med.Chem., 48, 2005
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4EGW
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![BU of 4egw by Molmil](/molmil-images/mine/4egw) | The structure of the soluble domain of CorA from Methanocaldococcus jannaschii | 分子名称: | 1,4-BUTANEDIOL, HEXANE-1,6-DIOL, MAGNESIUM ION, ... | 著者 | Guskov, A, Nordin, N, Reynaud, A, Engman, H, Lundback, A.-K, Jong, A.J.O, Cornvik, T, Phua, T, Eshaghi, S. | 登録日 | 2012-04-02 | 公開日 | 2012-10-31 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural insights into the mechanisms of Mg2+ uptake, transport, and gating by CorA Proc.Natl.Acad.Sci.USA, 109, 2012
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5N7E
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![BU of 5n7e by Molmil](/molmil-images/mine/5n7e) | Crystal structure of the Dbl-homology domain of Bcr-Abl in complex with monobody Mb(Bcr-DH_4). | 分子名称: | Breakpoint cluster region protein, Mb(Bcr-DH_4) | 著者 | Reckel, S, Reynaud, A, Pojer, F, Hantschel, O. | 登録日 | 2017-02-20 | 公開日 | 2017-12-27 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.647 Å) | 主引用文献 | Structural and functional dissection of the DH and PH domains of oncogenic Bcr-Abl tyrosine kinase. Nat Commun, 8, 2017
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5OC7
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![BU of 5oc7 by Molmil](/molmil-images/mine/5oc7) | Crystal structure of the pleckstrin-homology domain of Bcr-Abl in complex with monobody Mb(Bcr-PH_4). | 分子名称: | Breakpoint cluster region protein,pleckstrin-homology domain of Bcr-Abl, D-MYO-INOSITOL-4,5-BISPHOSPHATE, GLYCEROL, ... | 著者 | Reckel, S, Reynaud, A, Pojer, F, Hantschel, O. | 登録日 | 2017-06-29 | 公開日 | 2017-12-27 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.652 Å) | 主引用文献 | Structural and functional dissection of the DH and PH domains of oncogenic Bcr-Abl tyrosine kinase. Nat Commun, 8, 2017
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6R63
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![BU of 6r63 by Molmil](/molmil-images/mine/6r63) | Crystal structure of indoleamine 2,3-dioxygenase 1 (IDO1) in complex with ferric heme and MMG-0358 | 分子名称: | 4-chloranyl-2-(2~{H}-1,2,3-triazol-4-yl)phenol, Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Roehrig, U.F, Reynaud, A, Pojer, F, Michielin, O, Zoete, V. | 登録日 | 2019-03-26 | 公開日 | 2019-10-02 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.894 Å) | 主引用文献 | Inhibition Mechanisms of Indoleamine 2,3-Dioxygenase 1 (IDO1). J.Med.Chem., 62, 2019
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7AH4
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![BU of 7ah4 by Molmil](/molmil-images/mine/7ah4) | Crystal structure of indoleamine 2,3-dioxygenase 1 (IDO1) in complex with ferric heme and MMG-0363 | 分子名称: | 4-chloranyl-2-(2~{H}-1,2,3-triazol-4-yl)aniline, Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Roehrig, U.F, Reynaud, A, Pojer, F, Michielin, O, Zoete, V. | 登録日 | 2020-09-24 | 公開日 | 2021-02-17 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | 主引用文献 | Azole-Based Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors. J.Med.Chem., 64, 2021
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7AH6
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![BU of 7ah6 by Molmil](/molmil-images/mine/7ah6) | Crystal structure of indoleamine 2,3-dioxygenase 1 (IDO1) in complex with ferric heme and MMG-0752 | 分子名称: | 4-bromanyl-2-(4~{H}-1,2,4-triazol-3-yl)aniline, GLYCEROL, Indoleamine 2,3-dioxygenase 1, ... | 著者 | Roehrig, U.F, Reynaud, A, Pojer, F, Michielin, O, Zoete, V. | 登録日 | 2020-09-24 | 公開日 | 2021-02-17 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.998 Å) | 主引用文献 | Azole-Based Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors. J.Med.Chem., 64, 2021
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7AH5
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![BU of 7ah5 by Molmil](/molmil-images/mine/7ah5) | Crystal structure of indoleamine 2,3-dioxygenase 1 (IDO1) in complex with ferric heme and MMG-0706 | 分子名称: | 4-chloranyl-2-(1~{H}-1,2,4-triazol-5-yl)aniline, Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Roehrig, U.F, Reynaud, A, Pojer, F, Michielin, O, Zoete, V. | 登録日 | 2020-09-24 | 公開日 | 2021-02-17 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Azole-Based Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors. J.Med.Chem., 64, 2021
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3FKV
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![BU of 3fkv by Molmil](/molmil-images/mine/3fkv) | AmpC K67R mutant complexed with benzo(b)thiophene-2-boronic acid (bzb) | 分子名称: | BENZO[B]THIOPHENE-2-BORONIC ACID, Beta-lactamase, PHOSPHATE ION, ... | 著者 | Chen, Y, McReynolds, A, Shoichet, B.K. | 登録日 | 2008-12-17 | 公開日 | 2009-03-24 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.847 Å) | 主引用文献 | Re-examining the role of Lys67 in class C beta-lactamase catalysis. Protein Sci., 18, 2009
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4EL6
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![BU of 4el6 by Molmil](/molmil-images/mine/4el6) | Crystal structure of IPSE/alpha-1 from Schistosoma mansoni eggs | 分子名称: | IL-4-inducing protein | 著者 | Mayerhofer, H, Meyer, H, Tripsianes, K, Barths, D, Blindow, S, Bade, S, Madl, T, Frey, A, Haas, H, Sattler, M, Schramm, G, Mueller-Dieckmann, J. | 登録日 | 2012-04-10 | 公開日 | 2013-04-10 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Structure and functional analysis of IPSE/alpha-1, an IL-4-inducing factor secreted from Schistosoma mansoni eggs, reveals an IgE-binding crystallin fold To be Published
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3FKW
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4BA9
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![BU of 4ba9 by Molmil](/molmil-images/mine/4ba9) | The structural basis for the coordination of Y-family Translesion DNA Polymerases by Rev1 | 分子名称: | DNA POLYMERASE KAPPA, DNA REPAIR PROTEIN REV1, MAGNESIUM ION, ... | 著者 | Grummitt, C.G, Kilkenny, M.L, Frey, A, Roe, S.M, Oliver, A.W, Sale, J.E, Pearl, L.H. | 登録日 | 2012-09-12 | 公開日 | 2013-09-25 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | 主引用文献 | The Structural Basis for the Coordination of Y- Family Translesion DNA Polymerases by Rev1 To be Published
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4AKA
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![BU of 4aka by Molmil](/molmil-images/mine/4aka) | IPSE alpha-1, an IgE-binding crystallin | 分子名称: | IL-4-INDUCING PROTEIN | 著者 | Meyer, N.H, Mayerhofer, H, Tripsianes, K, Barths, D, Blindow, S, Bade, S, Madl, T, Frey, A, Haas, H, Mueller-Dieckmann, J, Sattler, M, Scharmm, G. | 登録日 | 2012-02-22 | 公開日 | 2013-03-13 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | A Crystallin Fold in the Interleukin-4-Inducing Principle of Schistosoma Mansoni Eggs (Ipse/Alpha-1) Mediates Ige Binding for Antigen-Independent Basophil Activation J.Biol.Chem., 290, 2015
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7ODF
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![BU of 7odf by Molmil](/molmil-images/mine/7odf) | Structure of the mini-RNA-guided endonuclease CRISPR-Cas_phi3 | 分子名称: | Cas_phi3, DNA (5'-D(P*GP*G)-3'), DNA (5'-D(P*GP*TP*AP*AP*TP*TP*CP*AP*G)-3'), ... | 著者 | Carabias del Rey, A, Fugilsang, A, Temperini, P, Pape, T, Sofos, N, Stella, S, Erledsson, S, Montoya, G. | 登録日 | 2021-04-29 | 公開日 | 2021-07-21 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.66 Å) | 主引用文献 | Structure of the mini-RNA-guided endonuclease CRISPR-Cas12j3. Nat Commun, 12, 2021
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8DBZ
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![BU of 8dbz by Molmil](/molmil-images/mine/8dbz) | |
2N4O
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![BU of 2n4o by Molmil](/molmil-images/mine/2n4o) | |
8QBM
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![BU of 8qbm by Molmil](/molmil-images/mine/8qbm) | |