1ZVI

Rat Neuronal Nitric Oxide Synthase Oxygenase Domain

Summary for 1ZVI

Entry DOI	10.2210/pdb1zvi/pdb
Related	1N2N 1QW4 1QW5 1QW6 1QWC 1VAG 1ZVL
Descriptor	Nitric-oxide synthase, brain, ZINC ION, PROTOPORPHYRIN IX CONTAINING FE, ... (5 entities in total)
Functional Keywords	rat nnosoxy, targeting tetrahydrobiopterin binding site, oxidoreductase
Biological source	Rattus norvegicus (Norway rat)
Cellular location	Cell membrane, sarcolemma ; Peripheral membrane protein : P29476
Total number of polymer chains	1
Total formula weight	49503.35
Authors	Matter, H.,Kumar, H.S.,Fedorov, R.,Frey, A.,Kotsonis, P.,Hartmann, E.,Frohlich, L.G.,Reif, A.,Pfleiderer, W.,Scheurer, P.,Ghosh, D.K.,Schlichting, I.,Schmidt, H.H. (deposition date: 2005-06-02, release date: 2005-08-02, Last modification date: 2024-02-14)
Primary citation	Matter, H.,Kumar, H.S.,Fedorov, R.,Frey, A.,Kotsonis, P.,Hartmann, E.,Frohlich, L.G.,Reif, A.,Pfleiderer, W.,Scheurer, P.,Ghosh, D.K.,Schlichting, I.,Schmidt, H.H. Structural Analysis of Isoform-Specific Inhibitors Targeting the Tetrahydrobiopterin Binding Site of Human Nitric Oxide Synthases. J.Med.Chem., 48:4783-4792, 2005 Cited by PubMed: 16033258 DOI: 10.1021/jm050007x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation