8OQ9
 
 | | Crystal structure of the titin domain Fn3-56 | | 分子名称: | CHLORIDE ION, Titin, ZINC ION | | 著者 | Rees, M, Gautel, M. | | 登録日 | 2023-04-11 | | 公開日 | 2023-08-23 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structure determination and analysis of titin A-band fibronectin type III domains provides insights for disease-linked variants and protein oligomerisation.
J.Struct.Biol., 215, 2023
|
|
8OMW
 | | Crystal structure of the titin domain Fn3-20 | | 分子名称: | CHLORIDE ION, Titin | | 著者 | Rees, M, Gautel, M. | | 登録日 | 2023-03-31 | | 公開日 | 2023-08-23 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | Structure determination and analysis of titin A-band fibronectin type III domains provides insights for disease-linked variants and protein oligomerisation.
J.Struct.Biol., 215, 2023
|
|
8ORL
 | |
8OIY
 | |
6MXT
 | | Crystal structure of human beta2 adrenergic receptor bound to salmeterol and Nb71 | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, Endolysin, ... | | 著者 | Masureel, M, Zou, Y, Picard, L.P, van der Westhuizen, E, Mahoney, J.P, Rodrigues, J.P.G.L.M, Mildorf, T.J, Dror, R.O, Shaw, D.E, Bouvier, M, Pardon, E, Steyaert, J, Sunahara, R.K, Weis, W.I, Zhang, C, Kobilka, B.K. | | 登録日 | 2018-10-31 | | 公開日 | 2018-11-14 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.95934224 Å) | | 主引用文献 | Structural insights into binding specificity, efficacy and bias of a beta2AR partial agonist.
Nat. Chem. Biol., 14, 2018
|
|
6RI7
 | | Cryo-EM structure of E. coli RNA polymerase elongation complex bound to GreB transcription factor | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Abdelkareem, M, Saint-Andre, C, Takacs, M, Papai, G, Crucifix, C, Guo, X, Ortiz, J, Weixlbaumer, A. | | 登録日 | 2019-04-23 | | 公開日 | 2019-07-03 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structural Basis of Transcription: RNA Polymerase Backtracking and Its Reactivation.
Mol.Cell, 75, 2019
|
|
6RH3
 | | Cryo-EM structure of E. coli RNA polymerase elongation complex bound to CTP substrate | | 分子名称: | CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Abdelkareem, M, Saint-Andre, C, Takacs, M, Papai, G, Crucifix, C, Guo, X, Ortiz, J, Weixlbaumer, A. | | 登録日 | 2019-04-18 | | 公開日 | 2019-07-03 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural Basis of Transcription: RNA Polymerase Backtracking and Its Reactivation.
Mol.Cell, 75, 2019
|
|
6RI9
 | | Cryo-EM structure of E. coli RNA polymerase backtracked elongation complex in non-swiveled state | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Abdelkareem, M, Saint-Andre, C, Takacs, M, Papai, G, Crucifix, C, Guo, X, Ortiz, J, Weixlbaumer, A. | | 登録日 | 2019-04-23 | | 公開日 | 2019-07-03 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural Basis of Transcription: RNA Polymerase Backtracking and Its Reactivation.
Mol.Cell, 75, 2019
|
|
6RIP
 | | Cryo-EM structure of E. coli RNA polymerase backtracked elongation complex in swiveled state | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Abdelkareem, M, Saint-Andre, C, Takacs, M, Papai, G, Crucifix, C, Guo, X, Ortiz, J, Weixlbaumer, A. | | 登録日 | 2019-04-24 | | 公開日 | 2019-07-03 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural Basis of Transcription: RNA Polymerase Backtracking and Its Reactivation.
Mol.Cell, 75, 2019
|
|
6RIN
 | | Cryo-EM structure of E. coli RNA polymerase backtracked elongation complex bound to GreB transcription factor | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Abdelkareem, M, Saint-Andre, C, Takacs, M, Papai, G, Crucifix, C, Guo, X, Ortiz, J, Weixlbaumer, A. | | 登録日 | 2019-04-24 | | 公開日 | 2019-07-03 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural Basis of Transcription: RNA Polymerase Backtracking and Its Reactivation.
Mol.Cell, 75, 2019
|
|
8OSD
 | |
8OS3
 | |
8OTY
 | |
8OT5
 | | Crystal structure of the titin domain Fn3-85 | | 分子名称: | CHLORIDE ION, SODIUM ION, Titin | | 著者 | Nikoopour, R, Rees, M, Gautel, M. | | 登録日 | 2023-04-20 | | 公開日 | 2023-08-23 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | Structure determination and analysis of titin A-band fibronectin type III domains provides insights for disease-linked variants and protein oligomerisation.
J.Struct.Biol., 215, 2023
|
|
4AQP
 | | The structure of the AXH domain of ataxin-1. | | 分子名称: | ATAXIN-1, DI(HYDROXYETHYL)ETHER, SODIUM ION | | 著者 | Rees, M, Chen, Y.W, de Chiara, C, Pastore, A. | | 登録日 | 2012-04-19 | | 公開日 | 2013-03-27 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.452 Å) | | 主引用文献 | Self-Assembly and Conformational Heterogeneity of the Axh Domain of Ataxin-1: An Unusual Example of a Chameleon Fold
Biophys.J., 104, 2013
|
|
4APT
 | | The structure of the AXH domain of ataxin-1. | | 分子名称: | ATAXIN-1, SODIUM ION | | 著者 | Rees, M, Chen, Y.W, de Chiara, C, Pastore, A. | | 登録日 | 2012-04-05 | | 公開日 | 2013-03-27 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Self-Assembly and Conformational Heterogeneity of the Axh Domain of Ataxin-1: An Unusual Example of a Chameleon Fold
Biophys.J., 104, 2013
|
|
2PYY
 | | Crystal Structure of the GluR0 ligand-binding core from Nostoc punctiforme in complex with (L)-glutamate | | 分子名称: | GLUTAMIC ACID, Ionotropic glutamate receptor bacterial homologue | | 著者 | Lee, J.H, Kang, G.B, Lim, H.-H, Ree, M, Park, C.-S, Eom, S.H. | | 登録日 | 2007-05-17 | | 公開日 | 2008-01-22 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of the GluR0 ligand-binding core from Nostoc punctiforme in complex with L-glutamate: structural dissection of the ligand interaction and subunit interface.
J.Mol.Biol., 376, 2008
|
|
8TLM
 | | Structure of a class A GPCR/Fab complex | | 分子名称: | C-C chemokine receptor type 8, Green fluorescent protein fusion, Fab heavy chain, ... | | 著者 | Sun, D, Johnson, M, Masureel, M. | | 登録日 | 2023-07-27 | | 公開日 | 2023-12-20 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8.
Nat Commun, 14, 2023
|
|
8U1U
 | | Structure of a class A GPCR/agonist complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C-C motif chemokine 1,C-C chemokine receptor type 8,EGFP fusion protein, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Sun, D, Johnson, M, Masureel, M. | | 登録日 | 2023-09-02 | | 公開日 | 2023-12-20 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8.
Nat Commun, 14, 2023
|
|
8U31
 | | Crystal structure of PD-1 in complex with a Fab | | 分子名称: | Fab heavy chain, Fab light chain, GLYCEROL, ... | | 著者 | Sun, D, Masureel, M. | | 登録日 | 2023-09-07 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | | 主引用文献 | Structure- and machine learning-guided engineering demonstrate that a non-canonical disulfide in an anti-PD-1 rabbit antibody does not impede antibody developability.
Mabs, 16, 2024
|
|
8U32
 | | Crystal structure of PD-1 in complex with a Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain, ... | | 著者 | Sun, D, Masureel, M. | | 登録日 | 2023-09-07 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Structure- and machine learning-guided engineering demonstrate that a non-canonical disulfide in an anti-PD-1 rabbit antibody does not impede antibody developability.
Mabs, 16, 2024
|
|
6U18
 | | Directed evolution of a biosensor selective for the macrolide antibiotic clarithromycin | | 分子名称: | CITRATE ANION, CLARITHROMYCIN, Erythromycin resistance repressor protein | | 著者 | Li, Y, Reed, M, Wright, H.T, Cropp, T.A, Williams, G. | | 登録日 | 2019-08-15 | | 公開日 | 2020-08-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Development of Genetically Encoded Biosensors for Reporting the Methyltransferase-Dependent Biosynthesis of Semisynthetic Macrolide Antibiotics.
Acs Synth Biol, 2021
|
|
6UP7
 | | neurotensin receptor and arrestin2 complex | | 分子名称: | ARG-ARG-PRO-TYR-ILE-LEU, Beta-arrestin-1, Neurotensin receptor type 1, ... | | 著者 | Qu, Q.H, Huang, W, Masureel, M, Janetzko, J, Kobilka, B.K, Skiniotis, G. | | 登録日 | 2019-10-16 | | 公開日 | 2020-02-26 | | 最終更新日 | 2020-06-17 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structure of the neurotensin receptor 1 in complex with beta-arrestin 1.
Nature, 579, 2020
|
|
8Q4G
 | | Thin filament from FIB milled relaxed left ventricular mouse myofibrils | | 分子名称: | Actin, alpha cardiac muscle 1, Tropomyosin alpha-1 chain | | 著者 | Tamborrini, D, Wang, Z, Wagner, T, Tacke, S, Stabrin, M, Grange, M, Kho, A.L, Bennet, P, Rees, M, Gautel, M, Raunser, S. | | 登録日 | 2023-08-06 | | 公開日 | 2023-11-01 | | 最終更新日 | 2023-12-06 | | 実験手法 | ELECTRON MICROSCOPY (8 Å) | | 主引用文献 | Structure of the native myosin filament in the relaxed cardiac sarcomere.
Nature, 623, 2023
|
|
3G04
 | | Crystal structure of the TSH receptor in complex with a thyroid-stimulating autoantibody | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HUMAN THYROID STIMULATING AUTOANTIBODY M22 HEAVY CHAIN, HUMAN THYROID STIMULATING AUTOANTIBODY M22 LIGHT CHAIN, ... | | 著者 | Sanders, J, Chirgadze, D.Y, Sanders, P, Baker, S, Sullivan, A, Bhardwaja, A, Bolton, J, Reeve, M, Nakatake, N, Evans, M, Richards, T, Powell, M, Miguel, R.N, Blundell, T.L, Furmaniak, J, Smith, B.R. | | 登録日 | 2009-01-27 | | 公開日 | 2009-08-04 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Crystal structure of the TSH receptor in complex with a thyroid-stimulating autoantibody
Thyroid, 17, 2007
|
|
