6RIP

Cryo-EM structure of E. coli RNA polymerase backtracked elongation complex in swiveled state

Summary for 6RIP

Related6RH3 6RI7 6RI9 6RIN
EMDB information4893
DescriptorNon-template DNA, Template DNA, DNA-directed RNA polymerase subunit alpha, ... (9 entities in total)
Functional Keywordse. coli rna polymerase, backtracking, elongation complex, transcription
Biological sourceEscherichia coli (strain K12)
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Total number of polymer chains8
Total molecular weight418179.75
Authors
Abdelkareem, M.,Saint-Andre, C.,Takacs, M.,Papai, G.,Crucifix, C.,Guo, X.,Ortiz, J.,Weixlbaumer, A. (deposition date: 2019-04-24, release date: 2019-07-03, Last modification date: 2019-08-07)
Primary citation
Abdelkareem, M.,Saint-Andre, C.,Takacs, M.,Papai, G.,Crucifix, C.,Guo, X.,Ortiz, J.,Weixlbaumer, A.
Structural Basis of Transcription: RNA Polymerase Backtracking and Its Reactivation.
Mol.Cell, 75:298-309.e4, 2019
PubMed: 31103420 (PDB entries with the same primary citation)
DOI: 10.1016/j.molcel.2019.04.029
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone18 0.1% 0.1% 0.40MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures