6C54
 
 | | Ebola nucleoprotein nucleocapsid-like assembly and the asymmetric unit | | 分子名称: | Nucleoprotein | | 著者 | Su, Z, Wu, C, Pintilie, G.D, Chiu, W, Amarasinghe, G.K, Leung, D.W. | | 登録日 | 2018-01-13 | | 公開日 | 2018-03-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (5.8 Å) | | 主引用文献 | Electron Cryo-microscopy Structure of Ebola Virus Nucleoprotein Reveals a Mechanism for Nucleocapsid-like Assembly.
Cell, 172, 2018
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7TNT
 | | The tubulin-based conoid from detergent-extract Toxoplasma gondii cells | | 分子名称: | Tubulin alpha chain, Tubulin beta chain | | 著者 | Sun, S.Y, Pintilie, G.D, Chen, M, Chiu, W. | | 登録日 | 2022-01-21 | | 公開日 | 2022-06-22 | | 実験手法 | ELECTRON MICROSCOPY (9.3 Å) | | 主引用文献 | Cryo-ET of Toxoplasma parasites gives subnanometer insight into tubulin-based structures.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7TNS
 | | Subpellicular microtubule from detergent-extract Toxoplasma gondii cells | | 分子名称: | Microtubule associated protein SPM1, PDI family protein, Tubulin alpha chain, ... | | 著者 | Sun, S.Y, Pintilie, G.D, Chen, M, Chiu, W. | | 登録日 | 2022-01-21 | | 公開日 | 2022-06-22 | | 実験手法 | ELECTRON MICROSCOPY (6.7 Å) | | 主引用文献 | Cryo-ET of Toxoplasma parasites gives subnanometer insight into tubulin-based structures.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7TNQ
 | | The symmetry-released subpellicular microtubule map from detergent-extracted Toxoplasma cells | | 分子名称: | Microtubule associated protein SPM1, PDI family protein, Tubulin alpha chain, ... | | 著者 | Sun, S.Y, Pintilie, G.D, Chen, M. | | 登録日 | 2022-01-21 | | 公開日 | 2022-06-22 | | 実験手法 | ELECTRON MICROSCOPY (8.4 Å) | | 主引用文献 | Cryo-ET of Toxoplasma parasites gives subnanometer insight into tubulin-based structures.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7RRP
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7FD4
 | | A complete three-dimensional structure of the Lon protease translocating a protein substrate (conformation 1) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Alpha-S1-casein, Lon protease, ... | | 著者 | Li, S, Hsieh, K, Kuo, C, Lee, S, Pintilie, G, Zhang, K, Chang, C. | | 登録日 | 2021-07-16 | | 公開日 | 2021-11-03 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | Complete three-dimensional structures of the Lon protease translocating a protein substrate.
Sci Adv, 7, 2021
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7FD5
 | | A complete three-dimensional structure of the Lon protease translocating a protein substrate (conformation 2) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Alpha-S1-casein, Lon protease, ... | | 著者 | Li, S, Hsieh, K, Kuo, C, Lee, S, Pintilie, G, Zhang, K, Chang, C. | | 登録日 | 2021-07-16 | | 公開日 | 2021-11-03 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | Complete three-dimensional structures of the Lon protease translocating a protein substrate.
Sci Adv, 7, 2021
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8FCG
 | | Cryo-EM structure of Chikungunya virus asymmetric unit | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Capsid protein, E1 glycoprotein, ... | | 著者 | Su, G.C, Chmielewsk, D, Kaelber, J, Pintilie, G, Chen, M, Jin, J, Auguste, A, Chiu, W. | | 登録日 | 2022-12-01 | | 公開日 | 2024-03-20 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | | 主引用文献 | Cryogenic electron microscopy and tomography reveal imperfect icosahedral symmetry in alphaviruses.
Pnas Nexus, 3, 2024
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8TA5
 | | Title: Cryo-EM structure of the human CLC-2 chloride channel transmembrane domain with asymmetric C-terminal | | 分子名称: | Chloride channel protein 2 | | 著者 | Xu, M, Neelands, T, Powers, A.S, Liu, Y, Miller, S, Pintilie, G, Du Bois, J, Dror, R.O, Chiu, W, Maduke, M. | | 登録日 | 2023-06-26 | | 公開日 | 2024-01-31 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | | 主引用文献 | CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism.
Elife, 12, 2024
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8TA4
 | | Cryo-EM structure of the human CLC-2 chloride channel transmembrane domain with symmetric C-terminal | | 分子名称: | CHLORIDE ION, Chloride channel protein 2 | | 著者 | Xu, M, Neelands, T, Powers, A.S, Liu, Y, Miller, S, Pintilie, G, Du Bois, J, Dror, R.O, Chiu, W, Maduke, M. | | 登録日 | 2023-06-26 | | 公開日 | 2024-01-31 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | | 主引用文献 | CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism.
Elife, 12, 2024
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8TA2
 | | Cryo-EM structure of the human CLC-2 chloride channel transmembrane domain with bound inhibitor AK-42 | | 分子名称: | 2-[[2,6-bis(chloranyl)-3-phenylmethoxy-phenyl]amino]pyridine-3-carboxylic acid, CHLORIDE ION, Chloride channel protein 2 | | 著者 | Xu, M, Neelands, T, Powers, A.S, Liu, Y, Miller, S, Pintilie, G, Du Bois, J, Dror, R.O, Chiu, W, Maduke, M. | | 登録日 | 2023-06-26 | | 公開日 | 2024-01-31 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (2.74 Å) | | 主引用文献 | CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism.
Elife, 12, 2024
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8TA3
 | | Cryo-EM structure of the human CLC-2 chloride channel transmembrane domain Apo state with resolved N-terminal hairpin | | 分子名称: | CHLORIDE ION, Chloride channel protein 2 | | 著者 | Xu, M, Neelands, T, Powers, A.S, Liu, Y, Miller, S, Pintilie, G, Du Bois, J, Dror, R.O, Chiu, W, Maduke, M. | | 登録日 | 2023-06-26 | | 公開日 | 2024-01-31 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (2.46 Å) | | 主引用文献 | CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism.
Elife, 12, 2024
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8TA6
 | | Cryo-EM structure of the human CLC-2 chloride channel C-terminal domain | | 分子名称: | Chloride channel protein 2 | | 著者 | Xu, M, Neelands, T, Powers, A.S, Liu, Y, Miller, S, Pintilie, G, Du Bois, J, Dror, R.O, Chiu, W, Maduke, M. | | 登録日 | 2023-06-26 | | 公開日 | 2024-01-31 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (4.03 Å) | | 主引用文献 | CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism.
Elife, 12, 2024
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6WQH
 | | Molecular basis for the ATPase-powered substrate translocation by the Lon AAA+ protease | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Ig2 substrate, Lon protease, ... | | 著者 | Zhang, K, Li, S, Hsiehb, K, Sub, S, Pintilie, G, Chiu, W, Chang, C. | | 登録日 | 2020-04-28 | | 公開日 | 2021-06-09 | | 最終更新日 | 2021-11-17 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Molecular basis for ATPase-powered substrate translocation by the Lon AAA+ protease.
J.Biol.Chem., 297, 2021
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6VQX
 | | Type I-F CRISPR-Csy complex with its inhibitor AcrF6 | | 分子名称: | AcrF6, CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, ... | | 著者 | Zhang, K, Li, S, Pintilie, G, Zhu, Y, Huang, Z, Chiu, W. | | 登録日 | 2020-02-06 | | 公開日 | 2020-03-11 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | | 主引用文献 | Inhibition mechanisms of AcrF9, AcrF8, and AcrF6 against type I-F CRISPR-Cas complex revealed by cryo-EM.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6VQW
 | | Type I-F CRISPR-Csy complex with its inhibitor AcrF8 | | 分子名称: | AcrF8, CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, ... | | 著者 | Zhang, K, Li, S, Pintilie, G, Zhu, Y, Huang, Z, Chiu, W. | | 登録日 | 2020-02-06 | | 公開日 | 2020-03-11 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.42 Å) | | 主引用文献 | Inhibition mechanisms of AcrF9, AcrF8, and AcrF6 against type I-F CRISPR-Cas complex revealed by cryo-EM.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6XRZ
 | | The 28-kDa Frameshift Stimulation Element from the SARS-CoV-2 RNA Genome | | 分子名称: | Frameshift Stimulation Element from the SARS-CoV-2 RNA Genome | | 著者 | Zhang, K, Zheludev, I, Hagey, R, Wu, M, Haslecker, R, Hou, Y, Kretsch, R, Pintilie, G, Rangan, R, Kladwang, W, Li, S, Pham, E, Souibgui, C, Baric, R, Sheahan, T, Souza, V, Glenn, J, Chiu, W, Das, R. | | 登録日 | 2020-07-14 | | 公開日 | 2020-08-19 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (6.9 Å) | | 主引用文献 | Cryo-electron Microscopy and Exploratory Antisense Targeting of the 28-kDa Frameshift Stimulation Element from the SARS-CoV-2 RNA Genome.
Biorxiv, 2020
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6VQV
 | | Type I-F CRISPR-Csy complex with its inhibitor AcrF9 | | 分子名称: | AcrF9, CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, ... | | 著者 | Zhang, K, Li, S, Pintilie, G, Zhu, Y, Huang, Z, Chiu, W. | | 登録日 | 2020-02-06 | | 公開日 | 2020-03-11 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (2.57 Å) | | 主引用文献 | Inhibition mechanisms of AcrF9, AcrF8, and AcrF6 against type I-F CRISPR-Cas complex revealed by cryo-EM.
Proc.Natl.Acad.Sci.USA, 117, 2020
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7TBH
 | | cryo-EM structure of MBP-KIX-apoferritin complex with peptide 7 | | 分子名称: | Isoform 2 of CREB-binding protein,Ferritin heavy chain, N-terminally processed, LEU-SER-ARG-ARG-PRO-SEP-TYR-ARG-LYS-ILE-LEU-ASN-ASP-LEU-SER-SER-ASP-ALA-PRO | | 著者 | Zhang, K, Horikoshi, N, Li, S, Powers, A, Hameedi, M, Pintilie, G, Chae, H, Khan, Y, Suomivuori, C, Dror, R, Sakamoto, K, Chiu, W, Wakatsuki, S. | | 登録日 | 2021-12-22 | | 公開日 | 2022-03-16 | | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | | 主引用文献 | Cryo-EM, Protein Engineering, and Simulation Enable the Development of Peptide Therapeutics against Acute Myeloid Leukemia.
Acs Cent.Sci., 8, 2022
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7TB3
 | | cryo-EM structure of MBP-KIX-apoferritin | | 分子名称: | Isoform 2 of CREB-binding protein,Ferritin heavy chain, N-terminally processed | | 著者 | Zhang, K, Horikoshi, N, Li, S, Powers, A, Hameedi, M, Pintilie, G, Chae, H, Khan, Y, Suomivuori, C, Dror, R, Sakamoto, K, Chiu, W, Wakatsuki, S. | | 登録日 | 2021-12-21 | | 公開日 | 2022-03-16 | | 実験手法 | ELECTRON MICROSCOPY (2.57 Å) | | 主引用文献 | Cryo-EM, Protein Engineering, and Simulation Enable the Development of Peptide Therapeutics against Acute Myeloid Leukemia.
Acs Cent.Sci., 8, 2022
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7EZ0
 | | Apo L-21 ScaI Tetrahymena ribozyme | | 分子名称: | Apo L-21 ScaI Tetrahymena ribozyme, MAGNESIUM ION | | 著者 | Su, Z, Zhang, K, Kappel, K, Luo, B, Das, R, Chiu, W. | | 登録日 | 2021-06-01 | | 公開日 | 2021-08-25 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | | 主引用文献 | Cryo-EM structures of full-length Tetrahymena ribozyme at 3.1 angstrom resolution.
Nature, 596, 2021
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7EZ2
 | | Holo L-16 ScaI Tetrahymena ribozyme | | 分子名称: | Holo L-16 ScaI Tetrahymena ribozyme, Holo L-16 ScaI Tetrahymena ribozyme S1, Holo L-16 ScaI Tetrahymena ribozyme S2, ... | | 著者 | Su, Z, Zhang, K, Kappel, K, Luo, B, Das, R, Chiu, W. | | 登録日 | 2021-06-01 | | 公開日 | 2021-08-25 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | | 主引用文献 | Cryo-EM structures of full-length Tetrahymena ribozyme at 3.1 angstrom resolution.
Nature, 596, 2021
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6NYL
 | | Helicobacter pylori Vacuolating Cytotoxin A Oligomeric Assembly 2c (OA-2c) | | 分子名称: | Vacuolating cytotoxin autotransporter | | 著者 | Zhang, K, Zhang, H, Li, S, Au, S, Chiu, W. | | 登録日 | 2019-02-11 | | 公開日 | 2019-03-27 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Cryo-EM structures ofHelicobacter pylorivacuolating cytotoxin A oligomeric assemblies at near-atomic resolution.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6NYN
 | | Helicobacter pylori Vacuolating Cytotoxin A Oligomeric Assembly 2e (OA-2e) | | 分子名称: | Vacuolating cytotoxin autotransporter | | 著者 | Zhang, K, Zhang, H, Li, S, Au, S, Chiu, W. | | 登録日 | 2019-02-11 | | 公開日 | 2019-03-27 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Cryo-EM structures ofHelicobacter pylorivacuolating cytotoxin A oligomeric assemblies at near-atomic resolution.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6PMO
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