1Y97
 
 | |
3KIO
 | | mouse RNase H2 complex | | 分子名称: | Ribonuclease H2 subunit A, Ribonuclease H2 subunit B, Ribonuclease H2 subunit C | | 著者 | Shaban, N, Harvey, S, Perrino, F.W, Hollis, T. | | 登録日 | 2009-11-02 | | 公開日 | 2009-11-17 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | The structure of the mammalian RNase H2 complex provides insight into RNA:DNA hybrid processing to prevent immune dysfunction.
J.Biol.Chem., 285, 2010
|
|
4WKJ
 | | Crystallographic Structure of a Dodecameric RNA-DNA Hybrid | | 分子名称: | DNA (5'-D(*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*C)-3'), MAGNESIUM ION, RNA (5'-R(*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*C)-3') | | 著者 | Davis, R.R, Shaban, N.M, Perrino, F.W, Hollis, T. | | 登録日 | 2014-10-02 | | 公開日 | 2014-10-22 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of RNA-DNA duplex provides insight into conformational changes induced by RNase H binding.
Cell Cycle, 14, 2015
|
|
7U8Y
 | | TREX1 Structural Studies Capture Small Molecule Inhibition and Implicate Novel DNA Dynamics | | 分子名称: | ALIZARIN RED, MANGANESE (II) ION, Three-prime repair exonuclease 1 | | 著者 | Hemphill, W.O, Harvey, S.E, Simpson, S.R, Smalley, T.L, Salsbury, F.R, Perrino, F.W, Hollis, T. | | 登録日 | 2022-03-09 | | 公開日 | 2023-03-15 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | | 主引用文献 | TREX1 Structural Studies Capture Small Molecule Inhibition and Implicate Novel DNA Dynamics
to be published
|
|
4YNQ
 | | TREX1-dsDNA complex | | 分子名称: | DNA (24-MER), DNA (5'-D(P*GP*TP*GP*CP*TP*GP*AP*CP*GP*TP*CP*AP*GP*CP*AP*CP*GP*AP*CP*G)-3'), MAGNESIUM ION, ... | | 著者 | Fye, J.M, Harvey, S, Perrino, F.W, Hollis, T. | | 登録日 | 2015-03-10 | | 公開日 | 2015-05-27 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Exonuclease TREX1 degrades double-stranded DNA to prevent spontaneous lupus-like inflammatory disease.
Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
3U6F
 | | Mouse TREX1 D200N mutant | | 分子名称: | 1,4-BUTANEDIOL, 5'-D(*GP*AP*CP*G)-3', MAGNESIUM ION, ... | | 著者 | Bailey, S.L, Harvey, S, Perrino, F.W, Hollis, T. | | 登録日 | 2011-10-12 | | 公開日 | 2011-12-28 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Defects in DNA degradation revealed in crystal structures of TREX1 exonuclease mutations linked to autoimmune disease.
Dna Repair, 11, 2012
|
|
3U3Y
 | | Mouse TREX1 D200H mutant | | 分子名称: | 1,4-BUTANEDIOL, 5'-D(*GP*AP*CP*G)-3', CALCIUM ION, ... | | 著者 | Bailey, S.L, Harvey, S, Perrino, F.W, Hollis, T. | | 登録日 | 2011-10-06 | | 公開日 | 2011-12-28 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Defects in DNA degradation revealed in crystal structures of TREX1 exonuclease mutations linked to autoimmune disease.
Dna Repair, 11, 2012
|
|
2IDO
 | | Structure of the E. coli Pol III epsilon-Hot proofreading complex | | 分子名称: | 1,2-ETHANEDIOL, DNA polymerase III epsilon subunit, Hot protein, ... | | 著者 | Kirby, T.W, Harvey, S, DeRose, E.F, Chalov, S, Chikova, A.K, Perrino, F.W, Schaaper, R.M, London, R.E, Pedersen, L.C. | | 登録日 | 2006-09-15 | | 公開日 | 2006-11-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure of the Escherichia coli DNA polymerase III epsilon-HOT proofreading complex.
J.Biol.Chem., 281, 2006
|
|
3EPG
 | |
3EPI
 | |
2OA8
 | | Crystal Structure of mTREX1 with ssDNA | | 分子名称: | 5'-D(*GP*AP*CP*G)-3', CALCIUM ION, Three prime repair exonuclease 1 | | 著者 | de Silva, U, Hollis, T. | | 登録日 | 2006-12-15 | | 公開日 | 2007-02-20 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The Crystal Structure of TREX1 Explains the 3' Nucleotide Specificity and Reveals a Polyproline II Helix for Protein Partnering.
J.Biol.Chem., 282, 2007
|
|
2IOC
 | |
3MXM
 | |
3MXJ
 | |
3MXI
 | |
3P5J
 | |
