2OA8

Crystal Structure of mTREX1 with ssDNA

Summary for 2OA8

• Entry DOI: 10.2210/pdb2oa8/pdb
• Descriptor: 5'-D(*GP*AP*CP*G)-3', Three prime repair exonuclease 1, CALCIUM ION, ... (4 entities in total)
• Functional Keywords: poly-proline helix, ssdna complex, dnaq family, hydrolase-dna complex, hydrolase/dna
• Biological source: Mus musculus (house mouse)
• Cellular location: Nucleus (By similarity): Q91XB0
• Total number of polymer chains: 4
• Total formula weight: 53759.69

Authors

de Silva, U.,Hollis, T. (deposition date: 2006-12-15, release date: 2007-02-20, Last modification date: 2023-11-15)

• Primary citation: de Silva, U.,Choudhury, S.,Bailey, S.L.,Harvey, S.,Perrino, F.W.,Hollis, T.; The Crystal Structure of TREX1 Explains the 3' Nucleotide Specificity and Reveals a Polyproline II Helix for Protein Partnering.; J.Biol.Chem., 282:10537-10543, 2007; PubMed: 17293595; DOI: 10.1074/jbc.M700039200

Experimental method

X-RAY DIFFRACTION (2.1 Å)