1Y97

The human TREX2 3' exonuclease structure suggests a mechanism for efficient non-processive DNA catalysis

Summary for 1Y97

Entry DOI	10.2210/pdb1y97/pdb
Descriptor	Three prime repair exonuclease 2 (2 entities in total)
Functional Keywords	trex2, exonuclease, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Nucleus (Probable): Q9BQ50
Total number of polymer chains	2
Total formula weight	52448.69
Authors	Perrino, F.W.,Harvey, S.,McMillin, S.,Hollis, T. (deposition date: 2004-12-14, release date: 2005-01-25, Last modification date: 2011-07-13)
Primary citation	Perrino, F.W.,Harvey, S.,McMillin, S.,Hollis, T. The Human TREX2 3' -> 5'-Exonuclease Structure Suggests a Mechanism for Efficient Nonprocessive DNA Catalysis. J.Biol.Chem., 280:15212-15218, 2005 Cited by PubMed: 15661738 DOI: 10.1074/jbc.M500108200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation