8VUA
 
 | | Structure of FabS1CE1-EPR-1, an elbow-locked high affinity antibody for the erythropoeitin receptor | | 分子名称: | S1CE1 VARIANT OF FAB-EPR-1 heavy chain, S1CE1 VARIANT OF FAB-EPR-1 light chain | | 著者 | Singer, A.U, Bruce, H.A, Pavlenco, A, Ploder, L, Luu, G, Blazer, L, Adams, J.J, Sidhu, S.S. | | 登録日 | 2024-01-29 | | 公開日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (3.27 Å) | | 主引用文献 | Antigen-binding fragments with improved crystal lattice packing and enhanced conformational flexibility at the elbow region as crystallization chaperones.
Protein Sci., 33, 2024
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8VVO
 | | Structure of FabS1CE2-EPR1-1 in complex with the erythropoietin receptor | | 分子名称: | CHLORIDE ION, Erythropoietin receptor, S1CE2 VARIANT OF FAB-EPR-1 heavy chain, ... | | 著者 | Singer, A.U, Bruce, H.A, Pavlenco, A, Ploder, L, Luu, G, Blazer, L, Adams, J.J, Sidhu, S.S. | | 登録日 | 2024-01-31 | | 公開日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | | 主引用文献 | Antigen-binding fragments with improved crystal lattice packing and enhanced conformational flexibility at the elbow region as crystallization chaperones.
Protein Sci., 33, 2024
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8VVM
 | | Structure of FabS1CE1-EPR1-1 in complex with the erythropoietin receptor | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Singer, A.U, Bruce, H.A, Pavlenco, A, Ploder, L, Luu, G, Blazer, L, Adams, J.J, Sidhu, S.S. | | 登録日 | 2024-01-31 | | 公開日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Antigen-binding fragments with improved crystal lattice packing and enhanced conformational flexibility at the elbow region as crystallization chaperones.
Protein Sci., 33, 2024
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8VU4
 | | Structure of FabS1CE4-EPR-1, an elbow-locked high affinity antibody for the erythropoeitin receptor | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Singer, A.U, Bruce, H.A, Pavlenco, A, Ploder, L, Luu, G, Blazer, L, Adams, J.J, Sidhu, S.S. | | 登録日 | 2024-01-28 | | 公開日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Antigen-binding fragments with improved crystal lattice packing and enhanced conformational flexibility at the elbow region as crystallization chaperones.
Protein Sci., 33, 2024
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8VUC
 | | Structure of FabS1CE2-EPR-1, an elbow-locked high affinity antibody for the erythropoeitin receptor | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, S1CE2 VARIANT OF FAB-EPR-1 heavy chain, ... | | 著者 | Singer, A.U, Bruce, H.A, Pavlenco, A, Ploder, L, Luu, G, Blazer, L, Adams, J.J, Sidhu, S.S. | | 登録日 | 2024-01-29 | | 公開日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Antigen-binding fragments with improved crystal lattice packing and enhanced conformational flexibility at the elbow region as crystallization chaperones.
Protein Sci., 33, 2024
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8VU1
 | | Structure of FabS1CE3-EPR-1, an elbow-locked high affinity antibody for the erythropoeitin receptor (trigonal form) | | 分子名称: | S1CE3 VARIANT OF FAB-EPR-1 heavy chain, S1CE3 VARIANT OF FAB-EPR-1 light chain | | 著者 | Singer, A.U, Bruce, H.A, Pavlenco, A, Ploder, L, Luu, G, Blazer, L, Adams, J.J, Sidhu, S.S. | | 登録日 | 2024-01-27 | | 公開日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (3.08 Å) | | 主引用文献 | Antigen-binding fragments with improved crystal lattice packing and enhanced conformational flexibility at the elbow region as crystallization chaperones.
Protein Sci., 33, 2024
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8VTR
 | | Structure of FabS1CE3-EPR-1, an elbow-locked high affinity antibody for the erythropoeitin receptor (orthorhombic form) | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, CITRIC ACID, ... | | 著者 | Singer, A.U, Bruce, H.A, Pavlenco, A, Ploder, L, Luu, G, Blazer, L, Adams, J.J, Sidhu, S.S. | | 登録日 | 2024-01-26 | | 公開日 | 2024-07-10 | | 最終更新日 | 2024-07-24 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Antigen-binding fragments with improved crystal lattice packing and enhanced conformational flexibility at the elbow region as crystallization chaperones.
Protein Sci., 33, 2024
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6OTC
 | | Synthetic Fab bound to Marburg virus VP35 interferon inhibitory domain | | 分子名称: | CHLORIDE ION, GLYCEROL, Polymerase cofactor VP35, ... | | 著者 | Amatya, P, Chen, G, Borek, D, Sidhu, S.S, Leung, D.W. | | 登録日 | 2019-05-02 | | 公開日 | 2019-06-05 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Inhibition of Marburg Virus RNA Synthesis by a Synthetic Anti-VP35 Antibody.
Acs Infect Dis., 5, 2019
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8VUI
 | | Structure of FabS1CE-EPR-1, an elbow-locked Fab, in complex with the erythropoeitin receptor | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, AMMONIUM ION, ... | | 著者 | Singer, A.U, Bruce, H.A, Blazer, L, Adams, J.J, Sidhu, S.S. | | 登録日 | 2024-01-29 | | 公開日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Antigen-binding fragments with improved crystal lattice packing and enhanced conformational flexibility at the elbow region as crystallization chaperones.
Protein Sci., 33, 2024
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7KMK
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7KLG
 | | SARS-CoV-2 RBD in complex with Fab 15033 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 15033 heavy chain, Fab 15033 light chain, ... | | 著者 | Li, Z, Rini, J.M. | | 登録日 | 2020-10-30 | | 公開日 | 2021-02-10 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Tetravalent SARS-CoV-2 Neutralizing Antibodies Show Enhanced Potency and Resistance to Escape Mutations.
J.Mol.Biol., 433, 2021
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7KML
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7KLH
 | | SARS-CoV-2 RBD in complex with Fab 15033-7 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 15033-7 heavy chain, Fab 15033-7 light chain, ... | | 著者 | Li, Z, Rini, J.M. | | 登録日 | 2020-10-30 | | 公開日 | 2021-02-10 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Tetravalent SARS-CoV-2 Neutralizing Antibodies Show Enhanced Potency and Resistance to Escape Mutations.
J.Mol.Biol., 433, 2021
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4K94
 | | Crystal structure of KIT D4D5 fragment in complex with anti-Kit antibody Fab19 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab19 heavy chain, Fab19 light chain, ... | | 著者 | Resheynyak, A.V, Boggon, T.J, Lax, I, Schlessinger, J. | | 登録日 | 2013-04-19 | | 公開日 | 2013-10-16 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for KIT receptor tyrosine kinase inhibition by antibodies targeting the D4 membrane-proximal region.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4K9E
 | | Crystal structure of KIT D4D5 fragment in complex with anti-Kit antibodies Fab79D | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Mast/stem cell growth factor receptor Kit, heavy chain, ... | | 著者 | Resheynyak, A.V, Boggon, T.J, Lax, I, Schlessinger, J. | | 登録日 | 2013-04-19 | | 公開日 | 2013-10-16 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural basis for KIT receptor tyrosine kinase inhibition by antibodies targeting the D4 membrane-proximal region.
Proc.Natl.Acad.Sci.USA, 110, 2013
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6C16
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6BVA
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6BYH
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8VTP
 | | Structure of FabS1CE-EPR-1, a high affinity antibody for the erythropoeitin receptor | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, AMMONIUM ION, ... | | 著者 | Singer, A.U, Bruce, H.A, Blazer, L, Adams, J.J, Sidhu, S.S. | | 登録日 | 2024-01-26 | | 公開日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Antigen-binding fragments with improved crystal lattice packing and enhanced conformational flexibility at the elbow region as crystallization chaperones.
Protein Sci., 33, 2024
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7KXJ
 | | SARS-CoV-2 spike protein in complex with Fab 15033-7, 3-"up", asymmetric | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 15033-7 heavy chain, ... | | 著者 | Li, Z, Rini, J. | | 登録日 | 2020-12-04 | | 公開日 | 2021-02-03 | | 最終更新日 | 2021-08-25 | | 実験手法 | ELECTRON MICROSCOPY (6.4 Å) | | 主引用文献 | Tetravalent SARS-CoV-2 Neutralizing Antibodies Show Enhanced Potency and Resistance to Escape Mutations.
J.Mol.Biol., 433, 2021
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7KXK
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