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5U94
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BU of 5u94 by Molmil
Crystal structure of the Mycobacterium tuberculosis PASTA kinase PknB in complex with the potential theraputic kinase inhibitor GSK690693.
分子名称: 4-{2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-piperidin-3-ylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl}-2-methylbut-3 -yn-2-ol, GLYCEROL, MAGNESIUM ION, ...
著者Wlodarchak, N, Satyshur, K, Striker, R.
登録日2016-12-15
公開日2017-12-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献In Silico Screen and Structural Analysis Identifies Bacterial Kinase Inhibitors which Act with beta-Lactams To Inhibit Mycobacterial Growth.
Mol. Pharm., 15, 2018
2K6Q
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BU of 2k6q by Molmil
LC3 p62 complex structure
分子名称: Microtubule-associated proteins 1A/1B light chain 3B, p62_peptide from Sequestosome-1
著者Noda, N, Kumeta, H, Nakatogawa, H, Satoo, K, Adachi, W, Ishii, J, Fujioka, Y, Ohsumi, Y, Inagaki, F.
登録日2008-07-17
公開日2008-09-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural basis of target recognition by ATG8/LC3 during selective autophagy
To be Published
4I5N
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BU of 4i5n by Molmil
Structural mechanism of trimeric PP2A holoenzyme involving PR70: insight for Cdc6 dephosphorylation
分子名称: CALCIUM ION, MANGANESE (II) ION, Microcystin-LR (MCLR) bound form, ...
著者Wlodarchak, N, Satyshur, K.A, Guo, F, Xing, Y.
登録日2012-11-28
公開日2013-05-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of the Ca(2+)-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation.
Cell Res., 23, 2013
4I5L
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BU of 4i5l by Molmil
Structural mechanism of trimeric PP2A holoenzyme involving PR70: insight for Cdc6 dephosphorylation
分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, MALONATE ION, ...
著者Wlodarchak, N, Satyshur, K.A, Guo, F, Xing, Y.
登録日2012-11-28
公開日2013-05-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Structure of the Ca(2+)-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation.
Cell Res., 23, 2013
3AXA
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BU of 3axa by Molmil
Crystal structure of afadin PDZ domain in complex with the C-terminal peptide from nectin-3
分子名称: Afadin, Nectin-3
著者Fujiwara, Y, Goda, N, Narita, H, Satomura, K, Nakagawa, A, Sakisaka, T, Suzuki, M, Hiroaki, H.
登録日2011-03-31
公開日2012-04-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Crystal structure of afadin PDZ domain-nectin-3 complex shows the structural plasticity of the ligand-binding site.
Protein Sci., 24, 2015
2EFS
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BU of 2efs by Molmil
Crystal structure of the C-terminal tropomyosin fragment with N- and C-terminal extensions of the leucine zipper at 2.0 angstroms resolution
分子名称: General control protein GCN4 and Tropomyosin 1 alpha chain
著者Minakata, S, Nitanai, Y, Maeda, K, Oda, N, Wakabayashi, K, Maeda, Y.
登録日2007-02-23
公開日2008-03-04
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Two crystal structures of tropomyosin C-terminal fragment 176-273: exposure of the hydrophobic core to the solvent destabilizes the tropomyosin molecule
To be Published
2EFR
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BU of 2efr by Molmil
Crystal structure of the c-terminal tropomyosin fragment with N- and C-terminal extensions of the leucine zipper at 1.8 angstroms resolution
分子名称: General control protein GCN4 and Tropomyosin 1 alpha chain
著者Minakata, S, Nitanai, Y, Maeda, K, Oda, N, Wakabayashi, K, Maeda, Y.
登録日2007-02-23
公開日2008-03-04
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Two crystal structures of tropomyosin C-terminal fragment 176-273: exposure of the hydrophobic core to the solvent destabilizes the tropomyosin molecule
To be Published
2D3E
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BU of 2d3e by Molmil
Crystal structure of the C-Terminal fragment of rabbit skeletal alpha-tropomyosin
分子名称: General control protein GCN4 and Tropomyosin 1 alpha chain
著者Nitanai, Y, Maeda, K, Oda, N, Minakata, S, Maeda, Y.
登録日2005-09-27
公開日2006-09-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The Crystal Structure of C-Terminal Fragment of Rabbit Skeletal Alpha-Tropomyosin; Crystallographic Evidence of Tropomyosin Bending
To be Published
2RQH
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BU of 2rqh by Molmil
Structure of GSPT1/ERF3A-PABC
分子名称: G1 to S phase transition 1, Polyadenylate-binding protein 1
著者Osawa, M, Nakanishi, T, Hosoda, N, Uchida, S, Hoshino, T, Katada, I, Shimada, I.
登録日2009-05-08
公開日2010-05-26
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Eukaryotic Translation Termination Factor Gspt/Erf3 Recognizes Pabp with Chemical Exchange Using Two Overlapping Motifs
To be Published
1WR0
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BU of 1wr0 by Molmil
Structural characterization of the MIT domain from human Vps4b
分子名称: SKD1 protein
著者Takasu, H, Jee, J.G, Ohno, A, Goda, N, Fujiwara, K, Tochio, H, Shirakawa, M, Hiroaki, H, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-10-07
公開日2005-08-02
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structural characterization of the MIT domain from human Vps4b
Biochem.Biophys.Res.Commun., 334, 2005
3VQF
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BU of 3vqf by Molmil
Crystal Structure Analysis of the PDZ Domain Derived from the Tight Junction Regulating Protein
分子名称: E3 ubiquitin-protein ligase LNX
著者Akiyoshi, Y, Hamada, D, Goda, N, Tenno, T, Narita, H, Nakagawa, A, Furuse, M, Suzuki, M, Hiroaki, H.
登録日2012-03-22
公開日2013-03-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.199 Å)
主引用文献Structural basis for down regulation of tight junction by PDZ-domain containing E3-Ubiquitin ligase
To be Published
8H1O
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BU of 8h1o by Molmil
Cryo-EM structure of KpFtsZ-monobody double helical tube
分子名称: Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, Mb(Ec/KpFtsZ_S1)
著者Fujita, J, Amesaka, H, Yoshizawa, T, Kuroda, N, Kamimura, N, Hara, M, Inoue, T, Namba, K, Tanaka, S, Matsumura, H.
登録日2022-10-03
公開日2023-08-02
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (2.67 Å)
主引用文献Structures of a FtsZ single protofilament and a double-helical tube in complex with a monobody.
Nat Commun, 14, 2023
8IBN
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BU of 8ibn by Molmil
Cryo-EM structure of KpFtsZ single filament
分子名称: Cell division protein FtsZ, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, POTASSIUM ION
著者Fujita, J, Amesaka, H, Yoshizawa, T, Kuroda, N, Kamimura, N, Hibino, K, Konishi, T, Kato, Y, Hara, M, Inoue, T, Namba, K, Tanaka, S, Matsumura, H.
登録日2023-02-10
公開日2023-08-02
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献Structures of a FtsZ single protofilament and a double-helical tube in complex with a monobody.
Nat Commun, 14, 2023
2RPA
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BU of 2rpa by Molmil
The solution structure of N-terminal domain of microtubule severing enzyme
分子名称: Katanin p60 ATPase-containing subunit A1
著者Iwaya, N, Kuwahara, Y, Unzai, S, Nagata, T, Tomii, K, Goda, N, Tochio, H, Shirakawa, M, Hiroaki, H.
登録日2008-05-13
公開日2009-05-26
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献A common substrate recognition mode conserved between katanin P60 and VPS4 governs microtubule severing and membrane skeleton reorganization
J.Biol.Chem., 285, 2010
2RRE
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BU of 2rre by Molmil
Structure and function of the N-terminal nucleolin binding domain of nuclear valocine containing protein like 2 (NVL2) harboring a nucleolar localization signal
分子名称: Putative uncharacterized protein
著者Fujiwara, Y, Fujiwara, K, Goda, N, Iwaya, N, Tenno, T, Shirakawa, M, Hiroaki, H.
登録日2010-08-03
公開日2011-04-06
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure and function of the N-terminal nucleolin binding domain of nuclear valosin-containing protein-like 2 (NVL2) harboring a nucleolar localization signal
J.Biol.Chem., 286, 2011
2RRI
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BU of 2rri by Molmil
NMR structure of vasoactive intestinal peptide in DPC Micelle
分子名称: Vasoactive intestinal peptide
著者Umetsu, Y, Tenno, T, Goda, N, Shirakawa, M, Ikegami, T, Hiroaki, H.
登録日2010-12-21
公開日2011-04-06
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural difference of vasoactive intestinal peptide in two distinct membrane-mimicking environments
Biochim.Biophys.Acta, 1814, 2011
2RRH
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BU of 2rrh by Molmil
NMR structure of vasoactive intestinal peptide in Methanol
分子名称: VIP peptides
著者Umetsu, Y, Tenno, T, Goda, N, Ikegami, T, Hiroaki, H.
登録日2010-11-12
公開日2011-04-06
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural difference of vasoactive intestinal peptide in two distinct membrane-mimicking environments.
Biochim.Biophys.Acta, 1814, 2011
2RQG
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BU of 2rqg by Molmil
Structure of GSPT1/ERF3A-PABC
分子名称: G1 to S phase transition 1, Polyadenylate-binding protein 1
著者Osawa, M, Nakanishi, T, Hosoda, N, Uchida, S, Hoshino, T, Katada, I, Shimada, I.
登録日2009-05-08
公開日2010-05-26
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Eukaryotic Translation Termination Factor Gspt/Erf3 Recognizes Pabp with Chemical Exchange Using Two Overlapping Motifs
To be Published
2RRM
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BU of 2rrm by Molmil
Interplay between phosphatidyl-inositol-phosphates and claudins upon binding to the 1st PDZ domain of zonula occludens 1
分子名称: Tight junction protein ZO-1
著者Hiroaki, H, Satomura, K, Goda, N, Umetsu, Y, Taniguchi, R, Ikegami, T, Furuse, M.
登録日2011-01-06
公開日2011-05-25
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献1H, 13C, and 15N resonance assignment of the first PDZ domain of mouse ZO-1
Biomol.Nmr Assign., 5, 2011
6KVP
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BU of 6kvp by Molmil
S. aureus FtsZ in complex with 3-(1-(5-bromo-4-(4-(trifluoromethyl)phenyl)oxazol-2-yl)ethoxy)-2,6-difluorobenzamide (compound 2)
分子名称: 3-[(1R)-1-[5-bromanyl-4-[4-(trifluoromethyl)phenyl]-1,3-oxazol-2-yl]ethoxy]-2,6-bis(fluoranyl)benzamide, CALCIUM ION, Cell division protein FtsZ, ...
著者Ferrer-Gonzalez, E, Fujita, J, Yoshizawa, T, Nelson, J.M, Pilch, A.J, Hillman, E, Ozawa, M, Kuroda, N, Parhi, A.K, LaVoie, E.J, Matsumura, H, Pilch, D.S.
登録日2019-09-05
公開日2020-01-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure-Guided Design of a Fluorescent Probe for the Visualization of FtsZ in Clinically Important Gram-Positive and Gram-Negative Bacterial Pathogens.
Sci Rep, 9, 2019
1WLF
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BU of 1wlf by Molmil
Structure of the N-terminal domain of PEX1 AAA-ATPase: Characterization of a putative adaptor-binding domain
分子名称: Peroxisome biogenesis factor 1, SULFATE ION
著者Shiozawa, K, Maita, N, Tomii, K, Seto, A, Goda, N, Tochio, H, Akiyama, Y, Shimizu, T, Shirakawa, M, Hiroaki, H.
登録日2004-06-25
公開日2004-09-07
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structure of the N-terminal Domain of PEX1 AAA-ATPase: CHARACTERIZATION OF A PUTATIVE ADAPTOR-BINDING DOMAIN
J.Biol.Chem., 279, 2004
6KVQ
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BU of 6kvq by Molmil
S. aureus FtsZ in complex with BOFP (compound 3)
分子名称: CALCIUM ION, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, ...
著者Ferrer-Gonzalez, E, Fujita, J, Yoshizawa, T, Nelson, J.M, Pilch, A.J, Hillman, E, Ozawa, M, Kuroda, N, Parhi, A.K, LaVoie, E.J, Matsumura, H, Pilch, D.S.
登録日2019-09-05
公開日2020-01-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure-Guided Design of a Fluorescent Probe for the Visualization of FtsZ in Clinically Important Gram-Positive and Gram-Negative Bacterial Pathogens.
Sci Rep, 9, 2019
7WH3
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BU of 7wh3 by Molmil
Solution structure of human stomatin SPFH domain in a phosphate buffer
分子名称: Stomatin
著者Kataoka, K, Tenno, T, Goda, N, Hibino, E, Hiroaki, H.
登録日2021-12-29
公開日2022-06-08
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献A cryptic phosphate-binding pocket on the SPFH domain of human stomatin that regulates a novel fibril-like self-assembly
Curr Res Struct Biol, 4, 2022
6LL5
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BU of 6ll5 by Molmil
Crystal structure of KpFtsZ (residues 11-316)
分子名称: Cell division protein FtsZ, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE
著者Yoshizawa, T, Fujita, J, Terakado, H, Ozawa, M, Kuroda, N, Tanaka, S, Uehara, R, Matsumura, H.
登録日2019-12-21
公開日2020-02-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structures of the cell-division protein FtsZ from Klebsiella pneumoniae and Escherichia coli.
Acta Crystallogr.,Sect.F, 76, 2020
6LL6
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BU of 6ll6 by Molmil
Crsyal structure of EcFtsZ (residues 11-316)
分子名称: Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE
著者Yoshizawa, T, Fujita, J, Terakada, H, Ozawa, M, Kuroda, N, Tanaka, S, Uehara, R, Matsumura, H.
登録日2019-12-21
公開日2020-02-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of the cell-division protein FtsZ from Klebsiella pneumoniae and Escherichia coli.
Acta Crystallogr.,Sect.F, 76, 2020

 

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