8U78
 
 | | Structure of a N-Me-D-Gln4,Lys10-teixobactin analogue | | 分子名称: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, CHLORIDE ION, N-Methyl-D-Gln4,Lys10-teixobactin | | 著者 | Nowick, J.S, Yang, H, Kreutzer, A.G. | | 登録日 | 2023-09-14 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Supramolecular Interactions of Teixobactin Analogues in the Crystal State.
J.Org.Chem., 89, 2024
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6E00
 | | Structure of a N-Me-p-iodo-D-Phe1,N-Me-D-Gln4,Lys10-teixobactin analogue | | 分子名称: | N-Me-p-iodo-D-Phe1,N-Me-D-Gln4,Lys10-teixobactin analogue, SULFATE ION | | 著者 | Nowick, J.S, Yang, H, Wierzbicki, M. | | 登録日 | 2018-07-05 | | 公開日 | 2018-10-17 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | X-ray Crystallographic Structure of a Teixobactin Derivative Reveals Amyloid-like Assembly.
J. Am. Chem. Soc., 140, 2018
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6PSL
 | | Structure of a N-Me-D-Gln4,D-aza-Thr8,Arg10-teixobactin analogue | | 分子名称: | CHLORIDE ION, teixobactin analogue | | 著者 | Nowick, J.S, Yang, H, Pishenko, A, Li, X. | | 登録日 | 2019-07-12 | | 公開日 | 2019-11-27 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Design, Synthesis, and Study of Lactam and Ring-Expanded Analogues of Teixobactin.
J.Org.Chem., 85, 2020
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4NTP
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5HOY
 | | X-ray crystallographic structure of an A-beta 17_36 beta-hairpin. X-ray diffractometer data set. (LVFFAEDCGSNKCAII(SAR)LMV). | | 分子名称: | Amyloid beta A4 protein, O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500) | | 著者 | Kreutzer, A.G, Spencer, R.K, Nowick, J.S. | | 登録日 | 2016-01-19 | | 公開日 | 2016-03-23 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.295 Å) | | 主引用文献 | X-ray Crystallographic Structures of a Trimer, Dodecamer, and Annular Pore Formed by an A beta 17-36 beta-Hairpin.
J.Am.Chem.Soc., 138, 2016
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4WC8
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4P4Y
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8GJC
 | | X-ray crystallographic structure of a beta-hairpin peptide derived from Abeta 17-35. (ORN)LVFFAED(ORN)GAI(N-Me-Ile)GLM | | 分子名称: | DI(HYDROXYETHYL)ETHER, METHIONINE, beta-hairpin peptide derived from Abeta 17-35, ... | | 著者 | Kreutzer, A.G, Ruttenberg, S.M, Nowick, J.S. | | 登録日 | 2023-03-15 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.431 Å) | | 主引用文献 | beta-Hairpin Alignment Alters Oligomer Formation in A beta-Derived Peptides.
Biochemistry, 63, 2024
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8GJD
 | | X-ray crystallographic structure of a beta-hairpin peptide derived from Abeta 17-36. (ORN)LVFFAED(ORN)AII(N-Me-Gly)LMV | | 分子名称: | Beta-hairpin peptide derived from Abeta 17-36, IODIDE ION | | 著者 | Kreutzer, A.G, Ruttenberg, S.M, Nowick, J.S, Truex, N.L. | | 登録日 | 2023-03-15 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | beta-Hairpin Alignment Alters Oligomer Formation in A beta-Derived Peptides.
Biochemistry, 63, 2024
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7JXO
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5W4H
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5W4I
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5W4J
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7RTZ
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4IVH
 | | Crystal structure of QKLVFFAED nonapeptide segment from amyloid beta incorporated into a macrocyclic beta-sheet template | | 分子名称: | SODIUM ION, TERTIARY-BUTYL ALCOHOL, cyclo[Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-(delta-linked-Orn)-Hao-Lys-Hao-(p-bromoPhe)-Thr-(delta-linked-Orn)] | | 著者 | Pham, J.D, Chim, N, Goulding, C.W, Nowick, J.S. | | 登録日 | 2013-01-22 | | 公開日 | 2013-07-31 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Structures of beta-Amyloid Peptide Oligomers
J.Am.Chem.Soc., 2013
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4X0S
 | | Hexamer formed by a macrocycle containing a sequence from beta-2-microglobulin (63-69). | | 分子名称: | CHLORIDE ION, ORN-TYR-LEU-LEU-PHI-TYR-VAL-GLU-ORN-LYS-VAL-ALA-MAA-ALA-VAL-LYS, SODIUM ION, ... | | 著者 | Spencer, R.K, Salveson, P.J, Nowick, J.S. | | 登録日 | 2014-11-23 | | 公開日 | 2015-05-06 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (2.032 Å) | | 主引用文献 | X-ray Crystallographic Structures of Oligomers of Peptides Derived from beta 2-Microglobulin.
J.Am.Chem.Soc., 137, 2015
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3T4G
 | | AIIGLMV segment from Alzheimer's Amyloid-Beta displayed on 54-membered macrocycle scaffold | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Cyclic pseudo-peptide (ORN)AIIGLMV(ORN)KF(HAO)(4BF)K | | 著者 | Zhao, M, Liu, C, Cheng, P.N, Eisenberg, D, Nowick, J.S. | | 登録日 | 2011-07-26 | | 公開日 | 2012-10-31 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Amyloid beta-sheet mimics that antagonize protein aggregation and reduce amyloid toxicity.
Nat Chem, 4, 2012
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3NI3
 | | 54-Membered ring macrocyclic beta-sheet peptide | | 分子名称: | 54-membered ring macrocyclic beta-sheet peptide, ISOPROPYL ALCOHOL | | 著者 | Sawaya, M.R, Eisenberg, D, Nowick, J.S, Korman, T.P, Khakshoor, O. | | 登録日 | 2010-06-15 | | 公開日 | 2010-09-15 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | | 主引用文献 | X-ray crystallographic structure of an artificial beta-sheet dimer.
J.Am.Chem.Soc., 132, 2010
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3Q9G
 | | VQIVY segment from Alzheimer's tau displayed on 42-membered macrocycle scaffold | | 分子名称: | ACETIC ACID, Cyclic pseudo-peptide VQIV(4BF)(ORN)(HAO)KL(ORN), GLYCEROL | | 著者 | Liu, C, Sawaya, M.R, Eisenberg, D, Nowick, J.S, Cheng, P, Zheng, J. | | 登録日 | 2011-01-07 | | 公開日 | 2011-06-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Characteristics of Amyloid-Related Oligomers Revealed by Crystal Structures of Macrocyclic beta-Sheet Mimics.
J.Am.Chem.Soc., 133, 2011
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3Q9J
 | | AIIFL segment derived from Alzheimer's Amyloid-Beta displayed on 42-membered macrocycle scaffold | | 分子名称: | CHLORIDE ION, Cyclic pseudo-peptide AIIFL(ORN)(HAO)YK(ORN), GLYCEROL, ... | | 著者 | Liu, C, Sawaya, M.R, Eisenberg, D, Nowick, J.S, Cheng, P, Zheng, J. | | 登録日 | 2011-01-07 | | 公開日 | 2011-06-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Characteristics of Amyloid-Related Oligomers Revealed by Crystal Structures of Macrocyclic beta-Sheet Mimics.
J.Am.Chem.Soc., 133, 2011
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3Q9I
 | | LVFFA segment from Alzheimer's Amyloid-Beta displayed on 42-membered macrocycle scaffold, bromide derivative | | 分子名称: | CHLORIDE ION, Cyclic pseudo-peptide LV(4BF)FA(ORN)(HAO)LK(ORN), GLYCEROL, ... | | 著者 | Liu, C, Sawaya, M.R, Eisenberg, D, Nowick, J.S, Cheng, P, Zheng, J. | | 登録日 | 2011-01-07 | | 公開日 | 2011-06-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Characteristics of Amyloid-Related Oligomers Revealed by Crystal Structures of Macrocyclic beta-Sheet Mimics.
J.Am.Chem.Soc., 133, 2011
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3Q9H
 | | LVFFA segment from Alzheimer's Amyloid-Beta displayed on 42-membered macrocycle scaffold | | 分子名称: | 1,4-BUTANEDIOL, Cyclic pseudo-peptide LVFFA(ORN)(HAO)LK(ORN), GLYCEROL, ... | | 著者 | Liu, C, Sawaya, M.R, Eisenberg, D, Nowick, J.S, Cheng, P, Zheng, J. | | 登録日 | 2011-01-07 | | 公開日 | 2011-06-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Characteristics of Amyloid-Related Oligomers Revealed by Crystal Structures of Macrocyclic beta-Sheet Mimics.
J.Am.Chem.Soc., 133, 2011
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8T0O
 | | Fab from mAb RB2AT_87 | | 分子名称: | CHLORIDE ION, RB2AT_87 Fab Heavy chain, RB2AT_87 Fab Light chain | | 著者 | Kreutzer, A.G, Malonis, R.J, Lai, J.R, Nowick, J.S. | | 登録日 | 2023-06-01 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Generation and Study of Antibodies against Two Triangular Trimers Derived from A beta.
Pept Sci (Hoboken), 116, 2024
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7U4P
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4Q8D
 | | Crystal structure of a macrocyclic beta-sheet peptide containing two beta-strands from amyloid beta residues 15-23 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, macrocyclic beta-sheet peptide incorporating residues amyloid beta 15-23 | | 著者 | Pham, J.D, Spencer, R.K, Chen, K.H, Nowick, J.S. | | 登録日 | 2014-04-26 | | 公開日 | 2014-08-13 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.746 Å) | | 主引用文献 | A Fibril-Like Assembly of Oligomers of a Peptide Derived from beta-Amyloid.
J.Am.Chem.Soc., 136, 2014
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