4NTP
Crystal structure of macrocycles containing A 17-23 (LV(PHI)FAED) and A 30-36 (AII(SAR)L(ORN)V)
Summary for 4NTP
Entry DOI | 10.2210/pdb4ntp/pdb |
Related | 4NTR 4NW8 4NW9 |
Descriptor | Cyclic hexadecapeptide (ORN)LV(PHI)FAED(ORN)AII(SAR)L(ORN)V, SODIUM ION, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | beta-sheet, beta-hairpin, amyloid, phe19 changed to p-iodo-phenylalanine, de novo protein, protein binding |
Biological source | synthetic construct |
Total number of polymer chains | 16 |
Total formula weight | 30447.65 |
Authors | Nowick, J.S.,Spencer, R.K.,Li, H. (deposition date: 2013-12-02, release date: 2014-04-02, Last modification date: 2020-10-21) |
Primary citation | Spencer, R.K.,Li, H.,Nowick, J.S. X-ray crystallographic structures of trimers and higher-order oligomeric assemblies of a peptide derived from A beta (17-36). J.Am.Chem.Soc., 136:5595-5598, 2014 Cited by PubMed: 24669800DOI: 10.1021/ja5017409 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.987 Å) |
Structure validation
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