7JXO

Triangular trimer of beta-hairpins derived from Abeta17-36 with an F20Cha mutation

Summary for 7JXO

Entry DOI	10.2210/pdb7jxo/pdb
Descriptor	Amyloid-beta 17-36 peptide (2 entities in total)
Functional Keywords	amyloid, oligomer, alzheimer's disease, beta-hairpin, de novo protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	3
Total formula weight	6662.03
Authors	Kreutzer, A.G.,Haerianardakani, S.,Nowick, J.S. (deposition date: 2020-08-27, release date: 2020-12-09, Last modification date: 2023-10-18)
Primary citation	Haerianardakani, S.,Kreutzer, A.G.,Salveson, P.J.,Samdin, T.D.,Guaglianone, G.E.,Nowick, J.S. Phenylalanine Mutation to Cyclohexylalanine Facilitates Triangular Trimer Formation by beta-Hairpins Derived from A beta. J.Am.Chem.Soc., 142:20708-20716, 2020 Cited by PubMed: 33237748 DOI: 10.1021/jacs.0c09281 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.81 Å)

Structure validation