4Q8D

Crystal structure of a macrocyclic beta-sheet peptide containing two beta-strands from amyloid beta residues 15-23

Summary for 4Q8D

Entry DOI	10.2210/pdb4q8d/pdb
Descriptor	macrocyclic beta-sheet peptide incorporating residues amyloid beta 15-23, (4S)-2-METHYL-2,4-PENTANEDIOL (3 entities in total)
Functional Keywords	beta-sheet, synthetic peptide, artificial macrocycle, de novo protein
Total number of polymer chains	2
Total formula weight	5037.19
Authors	Pham, J.D.,Spencer, R.K.,Chen, K.H.,Nowick, J.S. (deposition date: 2014-04-26, release date: 2014-08-13, Last modification date: 2023-11-15)
Primary citation	Pham, J.D.,Spencer, R.K.,Chen, K.H.,Nowick, J.S. A Fibril-Like Assembly of Oligomers of a Peptide Derived from beta-Amyloid. J.Am.Chem.Soc., 136:12682-12690, 2014 Cited by PubMed: 25068693 DOI: 10.1021/ja505713y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.746 Å)

Structure validation