4IVH

Crystal structure of QKLVFFAED nonapeptide segment from amyloid beta incorporated into a macrocyclic beta-sheet template

Summary for 4IVH

Entry DOI	10.2210/pdb4ivh/pdb
Descriptor	cyclo[Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-(delta-linked-Orn)-Hao-Lys-Hao-(p-bromoPhe)-Thr-(delta-linked-Orn)], TERTIARY-BUTYL ALCOHOL, SODIUM ION, ... (4 entities in total)
Functional Keywords	amyloid oligomer, de novo protein
Biological source	synthetic construct (synthetic)
Total number of polymer chains	1
Total formula weight	2349.39
Authors	Pham, J.D.,Chim, N.,Goulding, C.W.,Nowick, J.S. (deposition date: 2013-01-22, release date: 2013-07-31, Last modification date: 2023-11-15)
Primary citation	Pham, J.D.,Chim, N.,Goulding, C.W.,Nowick, J.S. Structures of beta-Amyloid Peptide Oligomers J.Am.Chem.Soc., 2013
Experimental method	X-RAY DIFFRACTION (1.77 Å)

Structure validation