1U5E
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1U5D
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1U5G
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1U5F
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2OTX
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4ZRT
| PTP1BC215S bound to Nephrin peptide substrate | 分子名称: | CHLORIDE ION, GLY-PRO-LEU-PTR-ASP-GLU, GLYCEROL, ... | 著者 | Selner, N.G, Bell, C.E, Pei, D. | 登録日 | 2015-05-12 | 公開日 | 2015-06-24 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Diverse levels of sequence selectivity and catalytic efficiency of protein-tyrosine phosphatases. Biochemistry, 53, 2014
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8VRB
| Structure of a synthetic antibody in complex with a class I MHC presenting a hapten-peptide conjugate | 分子名称: | AMG 510 (bound form), Beta-2-microglobulin, GTPase KRas, ... | 著者 | Maso, L, Bang, I, Koide, S. | 登録日 | 2024-01-20 | 公開日 | 2024-09-04 | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | 主引用文献 | Molecular basis for antibody recognition of multiple drug-peptide/MHC complexes. Proc.Natl.Acad.Sci.USA, 121, 2024
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8VR9
| Structure of a synthetic antibody in complex with a class I MHC presenting a hapten-peptide conjugate | 分子名称: | AMG 510 (bound form), Beta-2-microglobulin, GTPase KRas, ... | 著者 | Maso, L, Bang, I, Koide, S. | 登録日 | 2024-01-20 | 公開日 | 2024-09-04 | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | 主引用文献 | Molecular basis for antibody recognition of multiple drug-peptide/MHC complexes. Proc.Natl.Acad.Sci.USA, 121, 2024
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8VRA
| Structure of a synthetic antibody in complex with a class I MHC presenting a hapten-peptide conjugate | 分子名称: | AMG 510 (bound form), Beta-2-microglobulin, GTPase KRas, ... | 著者 | Maso, L, Bang, I, Koide, S. | 登録日 | 2024-01-20 | 公開日 | 2024-09-04 | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | 主引用文献 | Molecular basis for antibody recognition of multiple drug-peptide/MHC complexes. Proc.Natl.Acad.Sci.USA, 121, 2024
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7L0F
| Monobody 12VC3 Bound to HRAS(WT) | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GTPase HRas, MAGNESIUM ION, ... | 著者 | Teng, K.W, Hattori, T, Tsai, S, Koide, S. | 登録日 | 2020-12-11 | 公開日 | 2021-03-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Selective and noncovalent targeting of RAS mutants for inhibition and degradation. Nat Commun, 12, 2021
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7L0G
| Monobody 12VC1 Bound to HRAS(G12C) | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GTPase HRas, MAGNESIUM ION, ... | 著者 | Teng, K.W, Hattori, T, Tsai, S, Koide, S. | 登録日 | 2020-12-11 | 公開日 | 2021-03-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | 主引用文献 | Selective and noncovalent targeting of RAS mutants for inhibition and degradation. Nat Commun, 12, 2021
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7KEY
| Protein Tyrosine Phosphatase 1B, Apo | 分子名称: | ACETATE ION, MAGNESIUM ION, Tyrosine-protein phosphatase non-receptor type 1 | 著者 | Battaile, K.P, Chirgadze, Y, Ruzanov, M, Romanov, V, Lam, K, Gordon, R, Lin, A, Lam, R, Pai, E, Chirgadze, N. | 登録日 | 2020-10-13 | 公開日 | 2022-01-19 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.771 Å) | 主引用文献 | Signal transfer in human protein tyrosine phosphatase PTP1B from allosteric inhibitor P00058. J.Biomol.Struct.Dyn., 2021
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7KLX
| Protein Tyrosine Phosphatase 1B with inhibitor | 分子名称: | 2-(2,5-dimethyl-1H-pyrrol-1-yl)-5-hydroxybenzoic acid, MAGNESIUM ION, Tyrosine-protein phosphatase non-receptor type 1 | 著者 | Battaile, K.P, Chirgadze, Y, Ruzanov, M, Romanov, V, Lam, K, Gordon, R, Lin, A, Lam, R, Pai, E, Chirgadze, N. | 登録日 | 2020-11-01 | 公開日 | 2022-01-19 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.839 Å) | 主引用文献 | Signal transfer in human protein tyrosine phosphatase PTP1B from allosteric inhibitor P00058. J.Biomol.Struct.Dyn., 2021
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2MSD
| NMR data-driven model of GTPase KRas-GNP tethered to a lipid-bilayer nanodisc | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, GTPase KRas, ... | 著者 | Mazhab-Jafari, M, Stathopoulos, P, Marshall, C, Ikura, M. | 登録日 | 2014-07-29 | 公開日 | 2015-06-03 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site. Proc.Natl.Acad.Sci.USA, 112, 2015
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2MSE
| NMR data-driven model of GTPase KRas-GNP:ARafRBD complex tethered to a lipid-bilayer nanodisc | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, GTPase KRas, ... | 著者 | Mazhab-Jafari, M, Stathopoulos, P, Marshall, C, Ikura, M. | 登録日 | 2014-07-29 | 公開日 | 2015-06-03 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site. Proc.Natl.Acad.Sci.USA, 112, 2015
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2MSC
| NMR data-driven model of GTPase KRas-GDP tethered to a lipid-bilayer nanodisc | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, GTPase KRas, ... | 著者 | Mazhab-Jafari, M, Stathopoulos, P, Marshall, C, Ikura, M. | 登録日 | 2014-07-29 | 公開日 | 2015-06-03 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site. Proc.Natl.Acad.Sci.USA, 112, 2015
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