7KEY

Protein Tyrosine Phosphatase 1B, Apo

Summary for 7KEY

Entry DOI	10.2210/pdb7key/pdb
Descriptor	Tyrosine-protein phosphatase non-receptor type 1, ACETATE ION, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	insulin, regulation, hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	33004.01
Authors	Battaile, K.P.,Chirgadze, Y.,Ruzanov, M.,Romanov, V.,Lam, K.,Gordon, R.,Lin, A.,Lam, R.,Pai, E.,Chirgadze, N. (deposition date: 2020-10-13, release date: 2022-01-19, Last modification date: 2023-10-18)
Primary citation	Chirgadze, Y.N.,Battaile, K.P.,Likhachev, I.V.,Balabaev, N.K.,Gordon, R.D.,Romanov, V.,Lin, A.,Karisch, R.,Lam, R.,Ruzanov, M.,Brazhnikov, E.V.,Pai, E.F.,Neel, B.G.,Chirgadze, N.Y. Signal transfer in human protein tyrosine phosphatase PTP1B from allosteric inhibitor P00058. J.Biomol.Struct.Dyn., :1-10, 2021 Cited by PubMed: 34705594 DOI: 10.1080/07391102.2021.1994879 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.771 Å)

Structure validation