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5IFR
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BU of 5ifr by Molmil
Structure of the stable UBE2D3-UbDha conjugate
分子名称: GLYCEROL, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 D3
著者Pruneda, J.N, Mulder, M.P.C, Witting, K, Ovaa, H, Komander, D.
登録日2016-02-26
公開日2016-05-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymes.
Nat.Chem.Biol., 12, 2016
8C07
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BU of 8c07 by Molmil
Structure of HECT E3 UBR5 forming K48 linked Ubiquitin chains
分子名称: 5-azanylpentan-2-one, E3 ubiquitin-protein ligase UBR5, Polyubiquitin-B
著者Hehl, L.A, Prabu, J.R, Schulman, B.A.
登録日2022-12-16
公開日2023-08-23
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural snapshots along K48-linked ubiquitin chain formation by the HECT E3 UBR5.
Nat.Chem.Biol., 20, 2024
8C06
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BU of 8c06 by Molmil
Structure of Dimeric HECT E3 Ubiquitin Ligase UBR5
分子名称: E3 ubiquitin-protein ligase UBR5, ZINC ION
著者Hehl, L.A, Prabu, J.R, Schulman, B.A.
登録日2022-12-16
公開日2023-08-23
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural snapshots along K48-linked ubiquitin chain formation by the HECT E3 UBR5.
Nat.Chem.Biol., 20, 2024
5LRV
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BU of 5lrv by Molmil
Structure of Cezanne/OTUD7B OTU domain bound to Lys11-linked diubiquitin
分子名称: GLYCEROL, OTU domain-containing protein 7B, PHOSPHATE ION, ...
著者Mevissen, T.E.T, Kulathu, Y, Mulder, M.P.C, Geurink, P.P, Maslen, S.L, Gersch, M, Elliott, P.R, Burke, J.E, van Tol, B.D.M, Akutsu, M, El Oualid, F, Kawasaki, M, Freund, S.M.V, Ovaa, H, Komander, D.
登録日2016-08-22
公開日2016-10-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne.
Nature, 538, 2016
5LRU
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BU of 5lru by Molmil
Structure of Cezanne/OTUD7B OTU domain
分子名称: OTU domain-containing protein 7B
著者Mevissen, T.E.T, Kulathu, Y, Mulder, M.P.C, Geurink, P.P, Maslen, S.L, Gersch, M, Elliott, P.R, Burke, J.E, van Tol, B.D.M, Akutsu, M, El Oualid, F, Kawasaki, M, Freund, S.M.V, Ovaa, H, Komander, D.
登録日2016-08-22
公開日2016-10-19
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne.
Nature, 538, 2016
5LRW
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BU of 5lrw by Molmil
Structure of Cezanne/OTUD7B OTU domain bound to ubiquitin
分子名称: GLYCEROL, OTU domain-containing protein 7B, Polyubiquitin-B
著者Mevissen, T.E.T, Kulathu, Y, Mulder, M.P.C, Geurink, P.P, Maslen, S.L, Gersch, M, Elliott, P.R, Burke, J.E, van Tol, B.D.M, Akutsu, M, El Oualid, F, Kawasaki, M, Freund, S.M.V, Ovaa, H, Komander, D.
登録日2016-08-22
公開日2016-10-19
最終更新日2017-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne.
Nature, 538, 2016
5LRX
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BU of 5lrx by Molmil
Structure of A20 OTU domain bound to ubiquitin
分子名称: Polyubiquitin-B, Tumor necrosis factor alpha-induced protein 3
著者Mevissen, T.E.T, Kulathu, Y, Mulder, M.P.C, Geurink, P.P, Maslen, S.L, Gersch, M, Elliott, P.R, Burke, J.E, van Tol, B.D.M, Akutsu, M, El Oualid, F, Kawasaki, M, Freund, S.M.V, Ovaa, H, Komander, D.
登録日2016-08-22
公開日2016-10-19
最終更新日2017-09-13
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne.
Nature, 538, 2016
7B5N
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BU of 7b5n by Molmil
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-UBE2L3~Ub~ARIH1.
分子名称: 5-azanylpentan-2-one, Cullin-1, E3 ubiquitin-protein ligase ARIH1, ...
著者Horn-Ghetko, D, Prabu, J.R, Schulman, B.A.
登録日2020-12-05
公開日2021-02-10
最終更新日2021-03-10
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly.
Nature, 590, 2021
7B5R
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BU of 7b5r by Molmil
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27
分子名称: Cullin-1, Cyclin-A2, Cyclin-dependent kinase 2, ...
著者Horn-Ghetko, D, Prabu, J.R, Schulman, B.A.
登録日2020-12-07
公開日2021-02-10
最終更新日2021-03-10
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly.
Nature, 590, 2021
7B5S
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BU of 7b5s by Molmil
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-ARIH1 Ariadne. Transition State 1
分子名称: Cullin-1, E3 ubiquitin-protein ligase ARIH1, E3 ubiquitin-protein ligase RBX1, ...
著者Horn-Ghetko, D, Prabu, J.R, Schulman, B.A.
登録日2020-12-07
公開日2021-02-10
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly.
Nature, 590, 2021
7B5L
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BU of 7b5l by Molmil
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27-UBE2L3~Ub~ARIH1. Transition State 1
分子名称: 5-azanylpentan-2-one, Cullin-1, Cyclin-A2, ...
著者Horn-Ghetko, D, Prabu, J.R, Schulman, B.A.
登録日2020-12-04
公開日2021-02-10
最終更新日2021-03-10
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly.
Nature, 590, 2021
7B5M
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BU of 7b5m by Molmil
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-SKP2-CKSHS1-p27~Ub~ARIH1. Transition State 2
分子名称: Cullin-1, Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinases regulatory subunit 1, ...
著者Horn-Ghetko, D, Prabu, J.R, Schulman, B.A.
登録日2020-12-05
公開日2021-02-17
最終更新日2021-03-10
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly.
Nature, 590, 2021

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件を2024-09-04に公開中

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