5LRU

Structure of Cezanne/OTUD7B OTU domain

Summary for 5LRU

• Entry DOI: 10.2210/pdb5lru/pdb
• Descriptor: OTU domain-containing protein 7B (2 entities in total)
• Functional Keywords: hydrolase, protease, deubiquitinase, otu domain
• Biological source: Homo sapiens (Human)
• Cellular location: Cytoplasm : Q6GQQ9
• Total number of polymer chains: 1
• Total formula weight: 36360.38

Authors

Mevissen, T.E.T.,Kulathu, Y.,Mulder, M.P.C.,Geurink, P.P.,Maslen, S.L.,Gersch, M.,Elliott, P.R.,Burke, J.E.,van Tol, B.D.M.,Akutsu, M.,El Oualid, F.,Kawasaki, M.,Freund, S.M.V.,Ovaa, H.,Komander, D. (deposition date: 2016-08-22, release date: 2016-10-19, Last modification date: 2017-09-13)

• Primary citation: Mevissen, T.E.,Kulathu, Y.,Mulder, M.P.,Geurink, P.P.,Maslen, S.L.,Gersch, M.,Elliott, P.R.,Burke, J.E.,van Tol, B.D.,Akutsu, M.,El Oualid, F.,Kawasaki, M.,Freund, S.M.,Ovaa, H.,Komander, D.; Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne.; Nature, 538:402-405, 2016; PubMed: 27732584; DOI: 10.1038/nature19836

Experimental method

X-RAY DIFFRACTION (2.2 Å)