6I1D
 
 | | Structure of the Ysh1-Mpe1 nuclease complex from S.cerevisiae | | 分子名称: | Endoribonuclease YSH1, GLYCEROL, Protein MPE1, ... | | 著者 | Hill, C.H, Boreikaite, V, Kumar, A, Casanal, A, Kubik, P, Degliesposti, G, Maslen, S, Mariani, A, von Loeffelholz, O, Girbig, M, Skehel, M, Passmore, L.A. | | 登録日 | 2018-10-28 | | 公開日 | 2019-02-13 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Activation of the Endonuclease that Defines mRNA 3' Ends Requires Incorporation into an 8-Subunit Core Cleavage and Polyadenylation Factor Complex.
Mol.Cell, 73, 2019
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7OWG
 | | human DEPTOR in a complex with mutant human mTORC1 A1459P | | 分子名称: | DEP domain-containing mTOR-interacting protein, Regulatory-associated protein of mTOR, Serine/threonine-protein kinase mTOR, ... | | 著者 | Heimhalt, M, Berndt, A, Wagstaff, J, Anandapadamanaban, M, Perisic, O, Maslen, S, McLaughlin, S, Yu, W.-H, Masson, G.R, Boland, A, Ni, X, Yamashita, K, Murshudov, G.N, Skehel, M, Freund, S.M, Williams, R.L. | | 登録日 | 2021-06-18 | | 公開日 | 2021-09-08 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | | 主引用文献 | Bipartite binding and partial inhibition links DEPTOR and mTOR in a mutually antagonistic embrace.
Elife, 10, 2021
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5G04
 | | Structure of the human APC-Cdc20-Hsl1 complex | | 分子名称: | ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, ... | | 著者 | Zhang, S, Chang, L, Alfieri, C, Zhang, Z, Yang, J, Maslen, S, Skehel, M, Barford, D. | | 登録日 | 2016-03-16 | | 公開日 | 2016-05-25 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Molecular Mechanism of Apc/C Activation by Mitotic Phosphorylation.
Nature, 533, 2016
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5G05
 | | Cryo-EM structure of combined apo phosphorylated APC | | 分子名称: | ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, ... | | 著者 | Zhang, S, Chang, L, Alfieri, C, Zhang, Z, Yang, J, Maslen, S, Skehel, M, Barford, D. | | 登録日 | 2016-03-16 | | 公開日 | 2016-05-25 | | 最終更新日 | 2019-09-11 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Molecular Mechanism of Apc/C Activation by Mitotic Phosphorylation.
Nature, 533, 2016
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5LCW
 | | Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Mitotic checkpoint complex (APC/C-MCC) at 4.2 angstrom resolution | | 分子名称: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... | | 著者 | Alfieri, C, Chang, L, Zhang, Z, Yang, J, Maslen, S, Skehel, M, Barford, D. | | 登録日 | 2016-06-22 | | 公開日 | 2016-08-10 | | 最終更新日 | 2019-10-23 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Molecular basis of APC/C regulation by the spindle assembly checkpoint.
Nature, 536, 2016
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6U3E
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6U3G
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6EQI
 | | Structure of PINK1 bound to ubiquitin | | 分子名称: | GLYCEROL, Nb696, Serine/threonine-protein kinase PINK1, ... | | 著者 | Schubert, A.F, Gladkova, C, Pardon, E, Wagstaff, J.L, Freund, S.M.V, Steyaert, J, Maslen, S, Komander, D. | | 登録日 | 2017-10-13 | | 公開日 | 2017-11-08 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structure of PINK1 in complex with its substrate ubiquitin.
Nature, 552, 2017
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5NBB
 | | Structure of the C-terminal domain of the Escherichia Coli ProQ RNA binding protein | | 分子名称: | RNA chaperone ProQ | | 著者 | Gonzales, G, Hardwick, S, Maslen, S, Skehel, M, Holmqvist, E, Vogel, J, Bateman, A, Luisi, B, Broadhurst, R. | | 登録日 | 2017-03-01 | | 公開日 | 2017-05-03 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the Escherichia coli ProQ RNA-binding protein.
RNA, 23, 2017
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5NB9
 | | Structure of the N-terminal domain of the Escherichia Coli ProQ RNA binding protein | | 分子名称: | RNA chaperone ProQ | | 著者 | Gonzales, G, Hardwick, S, Maslen, S, Skehel, M, Holmqvist, E, Vogel, J, Bateman, A, Luisi, B, Broadhurst, R. | | 登録日 | 2017-03-01 | | 公開日 | 2017-05-03 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the Escherichia coli ProQ RNA-binding protein.
RNA, 23, 2017
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8RIL
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8RJW
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8RJ3
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8RK2
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6SRS
 | | Structure of the Fanconi anaemia core subcomplex | | 分子名称: | Fanconi anaemia protein FANCL, Unassigned secondary structure elements (central region, proposed FANCB-FAAP100), ... | | 著者 | Shakeel, S, Rajendra, E, Alcon, P, He, S, Scheres, S.H.W, Passmore, L.A. | | 登録日 | 2019-09-05 | | 公開日 | 2019-11-06 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | | 主引用文献 | Structure of the Fanconi anaemia monoubiquitin ligase complex.
Nature, 575, 2019
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6SRI
 | | Structure of the Fanconi anaemia core complex | | 分子名称: | Fanconi anaemia protein FANCL, Unassigned secondary structure elements (base region, proposed FANCC-FANC-E-FANCF), ... | | 著者 | Shakeel, S, Rajendra, E, Alcon, P, He, S, Scheres, S.H.W, Passmore, L.A. | | 登録日 | 2019-09-05 | | 公開日 | 2019-11-06 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structure of the Fanconi anaemia monoubiquitin ligase complex.
Nature, 575, 2019
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7OWD
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7OWC
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8OUY
 | | Human RAD51B-RAD51C-RAD51D-XRCC2 (BCDX2) complex, 3.4 A resolution | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA repair protein RAD51 homolog 2, ... | | 著者 | Greenhough, L.A, Liang, C.C, West, S.C. | | 登録日 | 2023-04-25 | | 公開日 | 2023-06-21 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure and function of the RAD51B-RAD51C-RAD51D-XRCC2 tumour suppressor.
Nature, 619, 2023
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8OUZ
 | | Human RAD51B-RAD51C-RAD51D-XRCC2 (BCDX2) complex, 2.2 A resolution | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA repair protein RAD51 homolog 2, ... | | 著者 | Greenhough, L.A, Liang, C.C, West, S.C. | | 登録日 | 2023-04-25 | | 公開日 | 2023-06-21 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | | 主引用文献 | Structure and function of the RAD51B-RAD51C-RAD51D-XRCC2 tumour suppressor.
Nature, 619, 2023
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6SWG
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7ZGP
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7ZGQ
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7ZGR
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5OHN
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