1JDH
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![BU of 1jdh by Molmil](/molmil-images/mine/1jdh) | CRYSTAL STRUCTURE OF BETA-CATENIN AND HTCF-4 | 分子名称: | BETA-CATENIN, hTcf-4 | 著者 | Graham, T.A, Ferkey, D.M, Mao, F, Kimelman, D, Xu, W. | 登録日 | 2001-06-13 | 公開日 | 2001-12-05 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Tcf4 can specifically recognize beta-catenin using alternative conformations. Nat.Struct.Biol., 8, 2001
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1G3J
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![BU of 1g3j by Molmil](/molmil-images/mine/1g3j) | CRYSTAL STRUCTURE OF THE XTCF3-CBD/BETA-CATENIN ARMADILLO REPEAT COMPLEX | 分子名称: | BETA-CATENIN ARMADILLO REPEAT REGION, TCF3-CBD (CATENIN BINDING DOMAIN) | 著者 | Graham, T.A, Weaver, C, Mao, F, Kimelman, D, Xu, W. | 登録日 | 2000-10-24 | 公開日 | 2000-12-11 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of a beta-catenin/Tcf complex. Cell(Cambridge,Mass.), 103, 2000
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6WZW
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![BU of 6wzw by Molmil](/molmil-images/mine/6wzw) | Ash1L SET domain in complex with AS-85 | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Histone-lysine N-methyltransferase ASH1L, N-{[3-(3-carbamothioylphenyl)-1-{1-[(trifluoromethyl)sulfonyl]piperidin-4-yl}-1H-indol-6-yl]methyl}azetidine-3-carboxamide, ... | 著者 | Li, H, Deng, J, Cierpicki, T, Grembecka, J. | 登録日 | 2020-05-14 | 公開日 | 2021-04-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity. Nat Commun, 12, 2021
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6X0P
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![BU of 6x0p by Molmil](/molmil-images/mine/6x0p) | Ash1L SET domain Q2265A mutant in complex with AS-5 | 分子名称: | 3-[6-(aminomethyl)-1-(2-hydroxyethyl)-1H-indol-3-yl]benzene-1-carbothioamide, Histone-lysine N-methyltransferase ASH1L, S-ADENOSYLMETHIONINE, ... | 著者 | Rogawski, D.S, Li, H, Borkin, D, Cierpicki, T, Grembecka, J. | 登録日 | 2020-05-17 | 公開日 | 2021-04-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity. Nat Commun, 12, 2021
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1I7X
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![BU of 1i7x by Molmil](/molmil-images/mine/1i7x) | BETA-CATENIN/E-CADHERIN COMPLEX | 分子名称: | BETA-CATENIN, EPITHELIAL-CADHERIN | 著者 | Huber, A.H, Weis, W.I. | 登録日 | 2001-03-10 | 公開日 | 2001-05-16 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin. Cell(Cambridge,Mass.), 105, 2001
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1I7W
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![BU of 1i7w by Molmil](/molmil-images/mine/1i7w) | BETA-CATENIN/PHOSPHORYLATED E-CADHERIN COMPLEX | 分子名称: | BETA-CATENIN, CHLORIDE ION, EPITHELIAL-CADHERIN, ... | 著者 | Huber, A.H, Weis, W.I. | 登録日 | 2001-03-10 | 公開日 | 2001-05-09 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin. Cell(Cambridge,Mass.), 105, 2001
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5BPP
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![BU of 5bpp by Molmil](/molmil-images/mine/5bpp) | Structure of human Leukotriene A4 hydrolase in complex with inhibitor 4AZ | 分子名称: | 2-(4-butoxyphenyl)-N-hydroxyacetamide, ACETATE ION, Leukotriene A-4 hydrolase, ... | 著者 | Huang, J, Dong, N.N, Xiao, Q, Ou, P.Y, Wu, D, Lu, W.Q. | 登録日 | 2015-05-28 | 公開日 | 2016-08-10 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Bufexamac ameliorates LPS-induced acute lung injury in mice by targeting LTA4H Sci Rep, 6, 2016
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6W5I
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![BU of 6w5i by Molmil](/molmil-images/mine/6w5i) | Cryo-EM structure of MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome (Class01) | 分子名称: | DNA (147-MER), Histone H2A, Histone H2B 1.1, ... | 著者 | Park, S.H, Lee, Y.T, Ayoub, A, Dou, Y, Cho, U. | 登録日 | 2020-03-13 | 公開日 | 2021-03-31 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (6.9 Å) | 主引用文献 | Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin. Nat Commun, 12, 2021
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6W5N
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![BU of 6w5n by Molmil](/molmil-images/mine/6w5n) | Cryo-EM structure of MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome (Class05) | 分子名称: | DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ... | 著者 | Park, S.H, Lee, Y.T, Ayoub, A, Dou, Y, Cho, U. | 登録日 | 2020-03-13 | 公開日 | 2021-03-31 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (6 Å) | 主引用文献 | Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin. Nat Commun, 12, 2021
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6W5M
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![BU of 6w5m by Molmil](/molmil-images/mine/6w5m) | Cryo-EM structure of MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome (Class02) | 分子名称: | DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ... | 著者 | Park, S.H, Lee, Y.T, Ayoub, A, Dou, Y, Cho, U. | 登録日 | 2020-03-13 | 公開日 | 2021-03-31 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin. Nat Commun, 12, 2021
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5YAX
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![BU of 5yax by Molmil](/molmil-images/mine/5yax) | Crystal structure of a human neutralizing antibody bound to a HBV preS1 peptide | 分子名称: | Large envelope protein, SODIUM ION, scFv1 antibody | 著者 | Liu, X, Zheng, S, Ye, K, Sui, J. | 登録日 | 2017-09-02 | 公開日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A potent human neutralizing antibody Fc-dependently reduces established HBV infections Elife, 6, 2017
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1JPP
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![BU of 1jpp by Molmil](/molmil-images/mine/1jpp) | |
1QRS
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![BU of 1qrs by Molmil](/molmil-images/mine/1qrs) | |
1QRT
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![BU of 1qrt by Molmil](/molmil-images/mine/1qrt) | |
1QRU
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![BU of 1qru by Molmil](/molmil-images/mine/1qru) | |